{"id":9119,"date":"2018-06-09T01:00:00","date_gmt":"2018-07-27T09:36:36","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e7%96%be%e7%97%85%e9%a3%8e%e9%99%a9%e9%94%90%e5%87%8f81%ef%bc%81fda%e4%bb%8a%e6%97%a5%e6%89%b9%e5%87%86%e7%99%bd%e8%a1%80%e7%97%85%e6%96%b0%e7%96%97%e6%b3%95\/"},"modified":"2018-07-27T17:36:38","modified_gmt":"2018-07-27T09:36:38","slug":"%e7%96%be%e7%97%85%e9%a3%8e%e9%99%a9%e9%94%90%e5%87%8f81%ef%bc%81fda%e4%bb%8a%e6%97%a5%e6%89%b9%e5%87%86%e7%99%bd%e8%a1%80%e7%97%85%e6%96%b0%e7%96%97%e6%b3%95","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/9119\/","title":{"rendered":"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"line-height: 1.75em;\"><span style=\"max-width: 100%;font-size: 15px;background-color: rgb(255, 255, 255);color: rgb(0, 112, 192);line-height: 22.4px;font-family: 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15px;\">\u672c\u6b21\u83b7\u6279\u7684\u8fd9\u6b3e\u8054\u5408\u7597\u6cd5\uff0c\u6709\u671b\u7ed9\u60a3\u8005\u5e26\u6765\u5e0c\u671b\u3002\u5176\u4e2d\uff0c\u7531\u827e\u4f2f\u7ef4\u4e0e\u57fa\u56e0\u6cf0\u514b\u5171\u540c\u5f00\u53d1\u7684<strong>Venclexta\u662f\u4e00\u6b3e\u9009\u62e9\u6027\u7684BCL-2\u6291\u5236\u5242<\/strong>\uff0c\u6291\u5236\u5728\u6162\u6027\u6dcb\u5df4\u6027\u767d\u8840\u75c5\u4e2d\u8fc7\u91cf\u8868\u8fbe\u7684BCL-2\u86cb\u767d\u3002\u8fd9\u6b3e\u86cb\u767d\u5728\u7ec6\u80de\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u7684\u8fc7\u7a0b\u4e2d\u8d77\u5230\u4e86\u91cd\u8981\u4f5c\u7528\uff0c\u800c\u6291\u5236\u5b83\u7684\u529f\u80fd\u6709\u671b\u91cd\u5851\u7ec6\u80de\u7684\u5173\u952e\u4fe1\u53f7\u901a\u8def\uff0c\u8ba9\u764c\u7ec6\u80de\u81ea\u6211\u6467\u6bc1\u3002<strong>Rituxan\u5219\u662f\u4e00\u6b3e\u9488\u5bf9CD20\u7684\u5355\u514b\u9686\u6297\u4f53<\/strong>\uff0c\u80fd\u6709\u6548\u5bf9\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u8fdb\u884c\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532684197.jpg\" alt=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\" title=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\"  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728\u4e00\u9879\u540d\u4e3aMURANO\u76843\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u8fd9\u6b3e\u8054\u5408\u7597\u6cd5\u7684\u6cbb\u7597\u6f5c\u529b\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002\u8be5\u7814\u7a76\u62db\u52df\u4e86389\u540d\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u6b21\u6cbb\u7597\u7684\u6162\u6027\u6dcb\u5df4\u6027\u767d\u8840\u75c5\u60a3\u8005\uff0c\u5e76\u5c06\u5176\u5206\u4e3a\u4e24\u7ec4\u3002\u5176\u4e2d\u4e00\u7ec4\u63a5\u53d7\u5316\u7597\u836f\u7269\u82ef\u8fbe\u83ab\u53f8\u6c40\uff08bendamustine\uff09\u4e0eRituxan\u7684\u6cbb\u7597\uff0c\u53e6\u4e00\u7ec4\u5219\u63a5\u53d7Venclexta\u4e0eRituxan\u7684\u6cbb\u7597\u3002<strong>\u7814\u7a76\u8868\u660e\uff0c\u76f8\u6bd4\u6807\u51c6\u6cbb\u7597\u65b9\u6848\uff0cVenclexta\u4e0eRituxan\u7684\u8054\u5408\u6cbb\u7597\u80fd\u663e\u8457\u51cf\u5c11\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u7684\u98ce\u9669\u8fbe81%\uff08HR = 0.19\uff1b95% CI\uff1a0.13-0.28\uff1bp &lt; 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alt=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\" title=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\"><\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);text-align: center;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(0, 112, 192);box-sizing: border-box !important;word-wrap: break-word !important;\">\u25b2\u672c\u7814\u7a76\u7684\u8bd5\u9a8c\u6570\u636e\uff08\u56fe\u7247\u6765\u6e90\uff1a\u57fa\u56e0\u6cf0\u514b\u5b98\u65b9\u7f51\u7ad9\uff09<\/span><\/strong><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c<strong>\u4e0e\u6807\u51c6\u7597\u6cd5\u76f8\u6bd4\uff0cVenclexta\u8ba9\u60a3\u8005\u6709\u4e86\u5168\u65b0\u7684\u65b9\u6cd5\uff0c\u6765\u663e\u8457\u51cf\u5c11\u4ed6\u4eec\u75be\u75c5\u8fdb\u5c55\u7684\u98ce\u9669\u3002<\/strong>\u8fd9\u4e00\u7ec4\u5408\u8ba9\u4e4b\u524d\u7ecf\u6cbb\u7684CLL\u6216SLL\u60a3\u8005\u80fd\u7528\u4e0a\u65e0\u9700\u5316\u7597\u7684\u5b9a\u65f6\u7597\u6cd5\uff0c\u8ba9\u60a3\u8005\u5728\u5927\u7ea62\u5e74\u540e\u505c\u6b62\u6cbb\u7597\uff0c\u201d\u827e\u4f2f\u7ef4\u9996\u5e2d\u79d1\u5b66\u5b98\u517c\u7814\u53d1\u6267\u884c\u526f\u603b\u88c1Michael Severino\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u8fd9\u5bf9\u60a3\u8005\u800c\u8a00\u662f\u91cd\u8981\u4e00\u6b65\u3002\u6211\u4eec\u671f\u5f85\u80fd\u7ee7\u7eed\u4e3a\u7f79\u60a3\u96be\u6cbb\u8840\u6db2\u764c\u75c7\u7684\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u65b9\u6848\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u201c\u6211\u4eec\u5f88\u9ad8\u5174Venclexta\u8fd9\u7c7b\u2018first of its kind\u2019\u7684\u9776\u5411\u7597\u6cd5\u80fd\u6765\u5230\u7ecf\u6cbb\u540e\u75be\u75c5\u590d\u53d1\u7684CLL\u60a3\u8005\u8eab\u8fb9\uff0c\u201d\u57fa\u56e0\u6cf0\u514b\u9996\u5e2d\u533b\u5b66\u5b98\u517c\u5168\u7403\u4ea7\u54c1\u5f00\u53d1\u8d1f\u8d23\u4ebaSandra Horning\u535a\u58eb\u8bf4\u9053\uff1a\u201cVenclexta\u4e0eRituxan\u5e26\u6765\u4e86\u5168\u65b0\u7684\u65e0\u5316\u7597\u65b9\u6848\uff0c<strong>\u4e14\u4e0e\u6807\u51c6\u7597\u6cd5\u76f8\u6bd4\uff0c\u5e2e\u52a9\u60a3\u8005\u4e0d\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\uff0c\u6d3b\u5f97\u66f4\u4e45\u3002<\/strong>\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u6211\u4eec\u795d\u8d3a\u8fd9\u6b3e\u65b0\u836f\u6210\u529f\u83b7\u6279\uff0c\u4e5f\u671f\u5f85\u7f79\u60a3\u96be\u6cbb\u767d\u8840\u75c5\u7684\u60a3\u8005\u80fd\u4ece\u4e2d\u5f97\u5230\u79ef\u6781\u6cbb\u7597\uff0c\u964d\u4f4e\u75be\u75c5\u98ce\u9669\uff01<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1] Genentech Announces FDA Approval for Venclexta Plus Rituxan for People with Previously Treated Chronic Lymphocytic Leukemia<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[2] AbbVie Announces U.S. FDA Approval of VENCLEXTA\u00ae (venetoclax tablets) in Combination with Rituximab as a Fixed Duration Treatment for Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Patients Who Have Received One Prior Therapy<\/span><\/p>\n<p><br  \/><\/p>\n<p><img class=\"\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress5-1532684197.gif\" alt=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\" title=\"\u75be\u75c5\u98ce\u9669\u9510\u51cf81%\uff01FDA\u4eca\u65e5\u6279\u51c6\u767d\u8840\u75c5\u65b0\u7597\u6cd5\"  \/><\/p>\n<\/p>\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u836f\u660e\u5eb7\u5fb7                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u4eca\u65e5\uff0c\u827e\u4f2f\u7ef4\uff08AbbVie\uff09\u4e0e\u57fa\u56e0\u6cf0\u514b\uff08Genentech\uff09\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u5df2\u6279\u51c6\u8fd9\u4e24\u5bb6\u516c\u53f8 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9120,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9119"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=9119"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9119\/revisions"}],"predecessor-version":[{"id":9125,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9119\/revisions\/9125"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/9120"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=9119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=9119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=9119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}