{"id":9126,"date":"2018-06-09T01:00:00","date_gmt":"2018-07-27T09:36:39","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e9%80%9f%e9%80%92-60%e5%b9%b4%e6%9d%a5%e7%aa%81%e7%a0%b4%ef%bc%81%e7%bd%97%e6%b0%8f%e6%96%b0%e8%8d%af%e8%8e%b7%e6%89%b9%e6%b2%bb%e7%96%97%e4%b8%a5%e9%87%8d%e5%85%8d%e7%96%ab%e7%96%be%e7%97%85\/"},"modified":"2018-07-27T17:36:40","modified_gmt":"2018-07-27T09:36:40","slug":"%e9%80%9f%e9%80%92-60%e5%b9%b4%e6%9d%a5%e7%aa%81%e7%a0%b4%ef%bc%81%e7%bd%97%e6%b0%8f%e6%96%b0%e8%8d%af%e8%8e%b7%e6%89%b9%e6%b2%bb%e7%96%97%e4%b8%a5%e9%87%8d%e5%85%8d%e7%96%ab%e7%96%be%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/9126\/","title":{"rendered":"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<h2 style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><\/h2>\n<p style=\"white-space: normal;\"><span style=\"max-width: 100%;font-size: 15px;background-color: rgb(255, 255, 255);color: rgb(0, 112, 192);line-height: 22.4px;font-family: \u6977\u4f53, \u6977\u4f53_GB2312, SimKai;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u258e\u836f\u660e<\/strong><\/span><strong style=\"max-width: 100%;color: rgb(62, 62, 62);font-size: 15px;background-color: rgb(255, 255, 255);line-height: 25.6px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);line-height: 22.4px;font-family: \u6977\u4f53, \u6977\u4f53_GB2312, SimKai;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/p>\n<p><strong style=\"max-width: 100%;color: rgb(62, 62, 62);font-size: 15px;background-color: rgb(255, 255, 255);line-height: 25.6px;font-family: \u5b8b\u4f53;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);line-height: 22.4px;font-family: \u6977\u4f53, \u6977\u4f53_GB2312, SimKai;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/span><\/strong><\/p>\n<h2 style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u65e5\u524d\uff0c\u7f57\u6c0f\u96c6\u56e2\uff08Roche Group\uff09\u6210\u5458\u57fa\u56e0\u6cf0\u514b\uff08Genentech\uff09\u5ba3\u5e03\uff0c<strong>\u7f8e\u56fdFDA\u6279\u51c6Rituxan\u00ae\uff08rituximab\uff0c\u5229\u59a5\u6614\u5355\u6297\uff09\u7528\u4e8e\u6cbb\u7597\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u5bfb\u5e38\u578b\u5929\u75b1\u75ae \uff08PV\uff09<\/strong>\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u5229\u59a5\u6614\u5355\u6297\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u7528\u4e8ePV\u7684\u751f\u7269\u7597\u6cd5\uff0c\u4e5f\u662f\u8be5\u75be\u75c5\u6cbb\u7597\u9886\u57df60\u591a\u5e74\u6765\u7684\u9996\u4e2a\u91cd\u5927\u8fdb\u5c55\u3002<\/span><br  \/><\/h2>\n<p><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"width: 528px;height: 142px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress6-1532684200.png\" alt=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\" title=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\"  \/><\/p>\n<p><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">PV\u662f\u5929\u75b1\u75ae\u7c7b\u75be\u75c5\u4e2d\u6700\u5e38\u89c1\u7684\u79cd\u7c7b\uff0c\u60a3\u8005\u5728\u76ae\u80a4\u6216\u8005\u7c98\u819c\u4e0a\u4f1a\u51fa\u73b0\u65e5\u6e10\u4e25\u91cd\u548c\u75bc\u75db\u7684\u6c34\u6ce1\u3002PV\u4ea7\u751f\u7684\u539f\u56e0\u662f\u514d\u75ab\u7cfb\u7edf\u4e2d\u4ea7\u751f\u653b\u51fb\u89d2\u8d28\u5f62\u6210\u7ec6\u80de (keratinocyte)\u7684\u6297\u4f53\u3002\u8fd9\u662f\u4e00\u79cd\u53ef\u80fd\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\uff0c\u60a3\u8005\u7684\u6b7b\u4ea1\u7387\u4e3a5-15%\u3002\u76ee\u524d\u5bf9\u8fd9\u79cd\u75be\u75c5\u7684\u6807\u51c6\u7597\u6cd5\u662f\u4f7f\u7528\u76ae\u8d28\u7c7b\u56fa\u9187 (CS) \u6fc0\u7d20\u6216\u8005\u514d\u75ab\u6291\u5236\u5242\u6765\u51cf\u5c11\u708e\u75c7\u7684\u4ea7\u751f\u3002<strong>\u4f46\u662f\u957f\u671f\u4f7f\u7528\u76ae\u8d28\u7c7b\u56fa\u9187\u53ef\u80fd\u7ed9\u60a3\u8005\u5e26\u6765\u4e25\u91cd\u5e76\u53ef\u80fd\u5371\u53ca\u751f\u547d\u7684\u526f\u4f5c\u7528<\/strong><strong>\uff0c\u56e0\u6b64\u8fd9\u4e9b\u60a3\u8005\u8feb\u5207\u9700\u8981\u65b0\u7684\u6cbb\u7597\u9009\u62e9<\/strong>\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u57fa\u56e0\u6cf0\u514b\u516c\u53f8\u5f00\u53d1\u7684Rituxan\u662f\u4e00\u79cdCD20\u5355\u514b\u9686\u6297\u4f53\uff0c\u5b83\u80fd\u591f\u6740\u4f24\u764c\u53d8\u7684CD20+ B\u6dcb\u5df4\u7ec6\u80de\u548c\u90e8\u5206\u6b63\u5e38B\u6dcb\u5df4\u7ec6\u80de<\/span><\/strong><span style=\"font-size: 15px;\">\uff0c\u6700\u521d\u88abFDA\u6279\u51c6\u6cbb\u7597\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u6162\u6027\u6dcb\u5df4\u6027\u767d\u8840\u75c5\u3002\u800c\u540e\uff0c<span style=\"font-size: 15px;\">Rituxan<\/span>\u7684\u9002\u5e94\u75c7\u6269\u5c55\u5230\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u6bd4\u5982\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u3002FDA\u66fe\u6388\u4e88\u8be5\u836f\u7269<\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649970500&amp;idx=5&amp;sn=f3011aeaa691f2a7c8b59baa69b11080&amp;chksm=82e9d1c4b59e58d26894406656aabf1ab53699beac967e6ef62ec0a5dcb5ed22a8695c95d2e3&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\"><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c<\/span><\/a><span style=\"font-size: 15px;\">\u3001\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u548c\u5b64\u513f\u836f\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597PV\u3002\u968f\u7740\u5bf9\u8fd9\u4e00\u9002\u5e94\u75c7\u7684\u6279\u51c6\uff0cRituxan\u73b0\u5728\u53ef\u7528\u4e8e4\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress4-1532684200.jpeg\" alt=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\" title=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\"  \/><\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Rituxan\u6cbb\u7597PV\u7684\u7597\u6548\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u4e5f\u5f97\u5230\u4e86\u8bc1\u5b9e\u3002\u4e00\u9879\u540d\u4e3aRitux 3\u7684\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\u5171\u62db\u52df\u4e8690\u540dPV\u60a3\u8005\uff0c\u4ed6\u4eec\u88ab\u968f\u673a\u5206\u6210\u4e24\u7ec4\uff0c\u4e00\u7ec4\u63a5\u53d7Ritux 3\u65b9\u6848\uff08\u6b27\u76df\u6279\u51c6\u7684\u5229\u59a5\u6614\u5355\u6297\u4ea7\u54c1\u52a0\u77ed\u671fCS\uff09\u6cbb\u7597\uff0c\u53e6\u4e00\u7ec4\u5355\u7528CS\u6cbb\u7597\u3002\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u662f24\u4e2a\u6708\u65f6\u7684\u5b8c\u5168\u7f13\u89e3\uff08\u4e0d\u4f7f\u7528\u7c7b\u56fa\u9187\u81f3\u5c112\u4e2a\u6708\uff09\u3002\u7ed3\u679c\u8868\u660e\uff0c<strong>\u7528Ritux 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Horning\u535a\u58eb\u8868\u793a\uff1a\u201cFDA\u7684\u51b3\u5b9a\u4e3a60\u591a\u5e74\u6765\u5bfb\u6c42\u5bfb\u5e38\u578b\u5929\u75b1\u75ae\u8fd9\u4e00\u53ef\u80fd\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\u7684\u60a3\u8005\u63d0\u4f9b\u4e86\u9996\u4e2a\u83b7\u5f97\u6279\u51c6\u7684\u6cbb\u7597\u65b9\u6848\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u4e3a\u60a3\u6709\u8fd9\u79cd\u4e25\u91cd\u75be\u75c5\u7684\u60a3\u8005\u63d0\u4f9bRituxan\u4f5c\u4e3a\u65b0\u7684\u6709\u6548\u7597\u6cd5\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<h2 style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1] FDA Approves Genentech\u2019s Rituxan (Rituximab) for Pemphigus Vulgaris<\/span><\/h2>\n<h3>\n<ul style=\"\" class=\"list-paddingleft-2\"><\/ul>\n<\/h3>\n<h1 class=\"entry-title\" style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[2] Rituxan\u83b7\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\uff0c\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5<\/span><\/h1>\n<p><br  \/><\/p>\n<p style=\"white-space: normal;\"><img class=\"__bg_gif\"      width=\"auto\" style=\"font-size: 16px;color: rgb(62, 62, 62);background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/07\/beepress2-1532684200.gif\" alt=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\" title=\"\u901f\u9012 | 60\u5e74\u6765\u7a81\u7834\uff01\u7f57\u6c0f\u65b0\u836f\u83b7\u6279\u6cbb\u7597\u4e25\u91cd\u514d\u75ab\u75be\u75c5\"  \/><\/p>\n<p style=\"white-space: normal;\">\n<blockquote class='keep-source'>\n<p>\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a                         \u836f\u660e\u5eb7\u5fb7                      <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u65e5\u524d\uff0c\u7f57\u6c0f\u96c6\u56e2\uff08Roche Group\uff09\u6210\u5458\u57fa\u56e0\u6cf0\u514b\uff08Genentech\uff09\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u6279 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