{"id":91274,"date":"2019-04-19T00:00:50","date_gmt":"2019-04-23T04:28:15","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/91274\/"},"modified":"2019-04-23T12:28:20","modified_gmt":"2019-04-23T04:28:20","slug":"c22512fa54","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/91274\/","title":{"rendered":"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a——\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317"},"content":{"rendered":"
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\u968f\u7740\u5168\u7403\u533b\u836f\u5e02\u573a\u7ade\u4e89\u4e0d\u65ad\u52a0\u5267\uff0c\u5404\u5927\u8de8\u56fd\u836f\u4f01\u7eb7\u7eb7\u53bb\u201c\u975e\u6838\u5fc3\u201d\u4e1a\u52a1\uff0c\u5316\u7e41\u4e3a\u7b80\uff0c\u56de\u5f52\u4f18\u52bf\u9886\u57df\u6216\u8005\u96c6\u4e2d\u529b\u91cf\u5f00\u62d3\u4e13\u4e1a\u9886\u57df\uff0c\u7136\u800c\u6709\u4e00\u5bb6\u836f\u4f01\uff0c\u5df2\u7ecf\u5728\u4e13\u4e1a\u5316\u7684\u9053\u8def\u4e0a\u8d70\u4e86\u6570\u5341\u5e74\uff0c\u5982\u4eca\u5df2\u9010\u6e10\u6210\u4e86\u8be5\u9886\u57df\u7684\u9886\u519b\u4f01\u4e1a\uff0c\u4ed6\u5c31\u662f\u4e39\u9ea6\u7075\u5317\uff0c\u4e00\u5bb6\u4e13\u6ce8\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u767e\u5e74\u836f\u4f01\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n


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\u4e39\u9ea6\u7075\u5317\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u6291\u90c1\u75c7\uff0c\u7cbe\u795e\u5206\u88c2\u75c7\uff0c\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u548c\u5e15\u91d1\u68ee\u7684\u5236\u836f\u516c\u53f8\u3002\u8fd9\u4e9b\u75be\u75c5\u662f\u4e16\u754c\u8303\u56f4\u5185\u6700\u81f4\u6b8b\u7684\u75be\u75c5\u79cd\u7c7b\u4e4b\u4e00\uff0c<\/span>\u4e5f\u662f\u793e\u4f1a\u8d1f\u62c5\u6781\u5927\u7684\u75c5\u79cd\u3002\u5728\u8fd9\u56db\u79cd\u75be\u75c5\u9886\u57df\uff0c\u4e39\u9ea6\u7075\u5317\u4e00\u76f4\u6df1\u8015\u7ec6\u4f5c\uff0c\u76ee\u524d\u5df2\u7ecf\u4e3a\u6570\u767e\u4e07\u60a3\u8005\u63d0\u4f9b\u4e86\u6cbb\u7597\u836f\u7269\u3002\u5f00\u53d1\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597\u836f\u7269\u662f\u4e00\u9879\u6781\u5176\u590d\u6742\u800c\u5145\u6ee1\u6311\u6218\u7684\u5de5\u4f5c\uff0c\u4f46\u7075\u5317\u9009\u62e9\u4e86\uff0c\u5e76\u4e00\u76f4\u575a\u6301\u7740\uff0c\u81f4\u529b\u4e8e\u786e\u4fdd\u60a3\u8005\u80fd\u591f\u66f4\u597d\u7684\u751f\u6d3b<\/span>\uff01<\/p>\n

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\u5c31\u662f\u8fd9\u4e48\u4e00\u5bb6\u4ee5\u4e13\u4e1a\u8457\u79f0\u7684\u516c\u53f8\uff0c\u8c01\u66fe\u60f3\u5230\u6700\u521d\u5374\u662f\u4e00\u5bb6\u7ecf\u8425\u5404\u79cd\u5546\u54c1\u7684\u8d38\u6613\u516c\u53f8\uff0c\u540e\u6765\u5728\u516c\u53f8\u4e0d\u65ad\u7684\u53d1\u5c55\u58ee\u5927\u8fc7\u7a0b\u4e2d\uff0c\u7075\u5317<\/span>\u6bc5\u7136\u6452\u5f03\u4e86\u5176\u4ed6\u884c\u4e1a\uff0c\u4e49\u65e0\u53cd\u987e\u7684\u4e13\u6ce8\u4e8e\u836f\u7269\u7814\u53d1\uff0c\u4e13\u6ce8\u4e8e\u8111\u90e8\u75be\u75c5\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf<\/span>\uff0c\u4ece\u800c\u6709\u4e86\u73b0\u5728\u6211\u4eec\u770b\u5230\u7684\u4e00\u5bb6\u4f9d\u9760\u7cbe\u795e\u548c\u795e\u7ecf\u6cbb\u7597\u836f\u7269\u95fb\u540d\u4e8e\u4e16\u7684\u8de8\u56fd\u4f01\u4e1a\uff01<\/span><\/p>\n

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\u53d1\u5c55\u53f2<\/strong><\/span><\/p>\n<\/section>\n


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\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u521b\u7acb\u521d\u671f\uff1a\u8d38\u6613\u8d77\u5bb6\uff0c\u6d89\u8db3\u533b\u836f\u521d\u5c1d\u6210\u679c\uff081915-1945\uff09<\/strong><\/p>\n<\/h2>\n<\/section>\n<\/section>\n


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1915\u5e7430\u5c81\u7684HansLundbeck\u5728\u4e39\u9ea6\u54e5\u672c\u54c8\u6839\u521b\u529e\u4e86\u7075\u5317\u516c\u53f8\uff0c\u4ed6\u96c7\u4f63\u7684\u9996\u4f4d\u5458\u5de5\u662f\u4e00\u4f4d\u5e74\u8f7b\u5973\u58ebGrete\uff0c\u540e\u6765\u6210\u4e3a\u4e86\u4ed6\u7684\u59bb\u5b50\u4ee5\u53ca\u7075\u5317\u57fa\u91d1\u4f1a\u7684\u521b\u59cb\u4eba\u3002\u7075\u5317\u516c\u53f8\u6700\u521d\u662f\u4e00\u5bb6\u8d38\u6613\u516c\u53f8\uff0c\u5411\u4e39\u9ea6\u5e02\u573a\u63d0\u4f9b\u5305\u62ec\u5236\u9020\u673a\u68b0\uff0c\u94dd\u7b94\uff0c\u4eba\u9020\u751c\u5473\u5242\u548c\u7167\u76f8\u8bbe\u5907\u7b49\u5404\u79cd\u5546\u54c1\u30021924\u5e74\u8058\u7528Eduard Goldschmidt\uff0c\u4ece\u800c\u8fdb\u5165\u4e86\u5236\u836f\u5e02\u573a\uff0c<\/span>\u5f53\u65f6\u4e3b\u8981\u4ece\u5176\u4ed6\u6b27\u7f8e\u56fd\u5bb6\u7684\u516c\u53f8\u8fdb\u53e3\u836f\u54c1\u548c\u5316\u5986\u54c1\u3002\u523020\u4e16\u7eaa30\u5e74\u4ee3\u540e\u671f\uff0c\u7075\u5317\u5f00\u59cb\u751f\u4ea7\u81ea\u5df1\u7684\u836f\u54c1\uff0c\u5e76\u5efa\u7acb\u4e86\u81ea\u5df1\u7684\u7814\u7a76\u90e8\u95e8\u3002<\/p>\n

 <\/p>\n

1937\u5e74\u4e39\u9ea6\u7075\u5317\u8058\u8bf7\u4e86\u7b2c\u4e00\u4e2a\u79d1\u5b66\u7814\u7a76\u5458\u836f\u5242\u5e08Oluf H\u00fcbner\uff0c\u7814\u53d1\u4e86\u7b2c\u4e00\u4e2a\u7528\u4e8e\u4f24\u53e3\u6108\u5408\u7684\u539f\u521b\u7684\u4ea7\u54c1Epicutan\u00ae\u3002Epicutan\u00ae\u7684\u6210\u529f\u4e3a\u7075\u5317\u5e26\u6765\u4e86\u56fd\u9645\u5316\u7684\u96c4\u5fc3\u548c\u4fe1\u5fc3\u3002\u521b\u65b0\u9a71\u52a8\u529b\uff0c\u81f3\u4eca\u4ecd\u7136\u662f\u7075\u5317\u7684\u7279\u8272\u3002<\/span>\u4e3a\u4e86\u786e\u4fdd\u6709\u8db3\u591f\u7684\u751f\u4ea7\u80fd\u529b\uff0c19<\/span>39\u5e74\u516c\u53f8\u642c\u5230\u4e86\u54e5\u672c\u54c8\u6839\u90ca\u533a\u7684Valby\uff0c\u7075\u5317\u7684\u603b\u90e8\u81f3\u4eca\u4f9d\u7136\u5728\u6b64\u3002<\/span>\u5728OlufH\u00fcbner\u7684\u5e26\u9886\u4e0b\uff0c\u7075\u5317\u5efa\u7acb\u4e86\u7b2c\u4e00\u4e2a\u5316\u5b66\u7814\u7a76\u5de5\u5382\uff0c\u4e3a\u5f00\u53d1\u5c3f\u8def\u611f\u67d3\u4ea7\u54c1Lucosil\u00ae\u63d0\u4f9b\u4e86\u5fc5\u8981\u7684\u73af\u5883\u3002<\/p>\n

 <\/p>\n

1943\u5e74Hans Lundbeck\u53bb\u4e16\uff0cPoul Viggo Petersen\u4e3b\u6301\u7075\u5317\u7684\u836f\u7269\u7814\u7a76\u3002Petersen\u4e8e1946\u5e74\u524d\u5f80\u5fb7\u56fd\u5e26\u56de\u4e00\u79cd\u5316\u5408\u7269\uff0c\u7075\u5317\u540e\u6765\u5c06\u8be5\u5316\u5408\u7269\u8fdb\u4e00\u6b65\u5f00\u53d1\u6210\u5f3a\u6548\u6b62\u75db\u836fKetogan\u00ae\uff0c<\/span>\u5176\u9547\u75db\u5f3a\u5ea6\u5927\u7ea6\u662f\u5417\u5561\u7684\u4e24\u500d\u3002Ketogan\u00ae\u7684\u9500\u552e\u7ed9\u7075\u5317\u5e26\u6765\u4e86\u53e6\u4e00\u4e2a\u5f3a\u52b2\u589e\u957f\u65f6\u671f\u3002 <\/span><\/p>\n


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\u4e13\u4e1a\u57fa\u7840\uff1a\u52a0\u5f3a\u836f\u7269\u7814\u53d1\uff0c\u5960\u5b9a\u57fa\u77f3\uff0c\u4e0d\u65ad\u6269\u5f20\uff081946-1970s\uff09<\/strong><\/p>\n<\/h2>\n<\/section>\n<\/section>\n


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\u7b2c\u4e8c\u6b21\u4e16\u754c\u5927\u6218\u540e\u7684\u51e0\u5e74\uff0c\u7075\u5317\u8fdb\u4e00\u6b65\u52a0\u5f3a\u79d1\u5b66\u7814\u7a76\uff0c\u8fd9\u4e9b\u7814\u7a76\u4e3a\u540e\u6765\u4f7f\u7075\u5317\u95fb\u540d\u4e8e\u4e16\u7684\u836f\u7269\u7814\u53d1\u5960\u5b9a\u4e86\u57fa\u77f3\u300220\u4e16\u7eaa50\u5e74\u4ee3\u521d\u5f00\u53d1\u4e86\u7b2c\u4e00\u6279\u6297\u751f\u7d20\u4ea7\u54c1Tyrosolvin\u548cTyrosolvetter\u3002\u5728\u6297\u751f\u7d20\u9886\u57df\u7684\u6295\u8d44\u7ec4\u5408\u4f7f\u7075\u5317\u5728\u7f8e\u56fd\u548c\u5176\u4ed6\u56fd\u9645\u5e02\u573a\u4e0a\u5360\u6709\u5f3a\u6709\u529b\u7684\u5730\u4f4d\u3002<\/p>\n

 <\/p>\n

1954\u5e74\u7075\u5317\u5f00\u59cb\u8fc8\u51fa\u8fdb\u5165\u7cbe\u795e\u6cbb\u7597\u9886\u57df\u7684\u7b2c\u4e00\u6b65<\/span>\uff0c\u83b7\u5f97\u5fb7\u56fd\u5236\u836f\u516c\u53f8Chemishe Fabrik Promonta\u5f00\u53d1\u7684Lacumin\u00ae\u7684\u9500\u552e\u8bb8\u53ef\u6743\u5229\u3002Lacumin\u00ae\u6ca1\u6709\u5927\u5356\uff0c\u4f46\u662f\u5374\u6fc0\u53d1\u4e86\u7075\u5317\u5f00\u53d1\u7cbe\u795e\u75be\u75c5\u836f\u7269\u7684\u5174\u8da3\u30021959\u5e74\u7075\u5317\u63a8\u51fa\u4e86\u4e16\u754c\u4e0a\u7b2c\u4e00\u4ee3\u6297\u7cbe\u795e\u75c5\u836f\u7269\u4e4b\u4e00\u7684Truxal\u00ae \uff0c\u572860\u548c70\u5e74\u4ee3Truxal\u00ae\u6210\u4e3a\u4e86\u7075\u5317\u6700\u7545\u9500\u7684\u4ea7\u54c1\uff0c\u4ece\u800c\u5f00\u542f\u4e86\u7075\u5317\u6297\u7cbe\u795e\u75c5\u836f\u7269\u7684\u65b0\u65f6\u4ee3\u3002<\/span><\/p>\n

 <\/p>\n

\u572860\u5e74\u4ee3\u521d\u7075\u5317\u63a8\u51fa\u4e86\u6297\u6291\u90c1\u836fSaroten\u00ae\uff08Amitriptyline\uff0c\u963f\u7c73\u66ff\u6797\uff09\uff0c\u8fd9\u6807\u5fd7\u7740\u7075\u5317\u5f00\u59cb\u5bf9\u6297\u6291\u90c1\u836f\u611f\u5174\u8da3\u3002<\/span>1960\u5e74\u81f31970\u5e74\u95f4\u7075\u5317\u5458\u5de5\u4eba\u6570\u7ffb\u500d\uff0c\u8fbe\u5230680\u4eba\uff0c\u5176\u4e2d\u7ea6100\u4eba\u5728\u56fd\u5916\u5c31\u4e1a\uff0c\u7075\u5317\u9010\u6e10\u6210\u4e3a\u4e00\u5bb6\u8de8\u56fd\u516c\u53f8\u30021969\u5e74\u5728\u7075\u5317\u4e1c\u4eac\u5f00\u8bbe\u4e86\u7b2c\u4e00\u5bb6\u65e5\u672c\u529e\u4e8b\u5904\u3002\u7075\u5317\u540e\u7eed\u8bb8\u591a\u91cd\u78c5\u836f\u7269\u90fd\u662f\u548c\u65e5\u672c\u516c\u53f8\u8054\u5408\u5f00\u53d1\u3002<\/p>\n

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\u805a\u7126\u7cbe\u795e\u795e\u7ecf\u836f\u7269\u5f00\u53d1\uff1a\u4e0a\u5e02\u5e76\u8d2d\uff0c\u4e13\u4e1a\u5316\u9053\u8def\u4e00\u8def\u5411\u524d\uff081970s\u672b-\u81f3\u4eca\uff09<\/strong>
<\/p>\n<\/h2>\n<\/section>\n<\/section>\n


<\/p>\n

20\u4e16\u7eaa70\u5e74\u4ee3<\/span>\u672b\u7075\u5317\u51b3\u5b9a\u9010\u6b65\u6dd8\u6c70\u73b0\u6709\u7684\u4ee3\u7406\u548c\u5316\u5986\u54c1\u90e8\u95e8\uff0c\u4e13\u6ce8\u4e8e\u836f\u54c1<\/span>\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u300220\u4e16\u7eaa80\u5e74\u4ee3\u672b\uff0c\u7075\u5317\u8fdb\u4e00\u6b65\u5f3a\u5316\u5176\u4e1a\u52a1\u6218\u7565\u91cd\u70b9\uff0c\u81f4\u529b\u4e8e\u8111\u75be\u75c5\u6cbb\u7597\u836f\u7269\u7684\u7814\u53d1<\/span>\u3001\u5236\u9020\u548c\u5546\u4e1a\u5316\u3002<\/p>\n

 <\/p>\n

1989\u5e74\u63a8\u51faCipramil\u00ae\uff08Citalopram\uff0c\u897f\u915e\u666e\u5170\uff09\uff0c\u7528\u4e8e\u6291\u90c1\u75c7\u7684\u6cbb\u7597\uff0cCipramil\u00ae\u76ee\u524d\u5df2\u572870\u591a\u4e2a\u56fd\u5bb6\u4e0a\u5e02\u30021999\u5e746\u6708\u7075\u5317\u516c\u53f8\u5728\u54e5\u672c\u54c8\u6839\u8bc1\u5238\u4ea4\u6613\u6240\uff08KFX\uff09\u4e0a\u5e02\u30022002\u5e74\u77e5\u540d\u836f\u7269Cipralex\u00ae\/Lexapro\u00ae\uff08Escitalopram\uff0c\u827e\u53f8\u897f\u915e\u666e\u5170\uff09\u4e0a\u5e02\uff0cCipralex\u00ae\/Lexapro\u00ae\u4e3a\u4e39\u9ea6\u7075\u5317\u8d21\u732e\u4e86\u5de8\u5927\u7684\u9500\u552e\u989d\uff0c\u6210\u4e3a\u6291\u90c1\u75c7\u6cbb\u7597\u4e2d\u4e16\u754c\u8303\u56f4\u5185\u7684\u9886\u8896\u836f\u7269\u3002<\/span><\/p>\n

 <\/p>\n

2003\u5e74\u7075\u5317\u6536\u8d2d\u7f8e\u56fd\u7814\u7a76\u516c\u53f8Synaptic\uff0c\u4ece\u800c\u5728\u7f8e\u56fd\u5efa\u7acb\u4e86\u7814\u7a76\u5355\u4f4d\u30022009\u5e74\u7075\u5317\u6536\u8d2d\u7f8e\u56fdOvation\u5236\u836f\u516c\u53f8\uff0c\u63a8\u51faSabril\u00ae\uff08Vigabatrin\uff0c\u6c28\u5df1\u70ef\u9178\uff09\u7528\u4e8e\u766b\u75eb\u7684\u6cbb\u7597\u3002\u7075\u5317\u8fd8\u901a\u8fc7\u6536\u8d2d\u6cd5\u56fdElaiapharm\u516c\u53f8\u8fdb\u4e00\u6b65\u63d0\u9ad8\u4e86\u751f\u4ea7\u80fd\u529b<\/span>\u3002<\/p>\n

 <\/p>\n

2011\u5e74\u7075\u5317\u63a8\u51faSaphris\u00ae\/Sycrest\u00ae\uff08Asenapine\uff0c\u963f\u585e\u90a3\u5e73\uff09\u7528\u4e8e\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u53cc\u76f8\u60c5\u611f\u969c\u788d\u30022012\u5e74Onfi\u00ae\uff08Clobazam\uff0c\u6c2f\u5df4\u5360\uff09\u4e0a\u5e02\u4e3a\u60a3Lennox-Gastaut\u7efc\u5408\u5f81\u7684\u60a3\u8005\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/span>2013\u5e74\u7075\u5317\u5728\u6b27\u6d32\u63a8\u51fa\u7528\u4e8e\u6cbb\u7597\u9152\u7cbe\u4f9d\u8d56\u7684Selincro\u00ae\uff08Nalmefene\uff0c\u7eb3\u7f8e\u82ac\uff09\u30022014\u5e74\uff0cBrintellix\u00ae\/Trintellix\u00ae\uff08Vortioxetine\uff0c\u4f0f\u786b\u897f\u6c40\uff09\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u91cd\u5ea6\u6291\u90c1\u30022014\u5e74\u7075\u5317\u6536\u8d2dChelsea Therapeutics\u516c\u53f8\uff0c\u83b7\u5f97\u6cbb\u7597\u795e\u7ecf\u6e90\u6027\u4f53\u4f4d\u6027\u4f4e\u8840\u538b\u7684Northera\u00ae\uff08Droxidopa\uff0c\u5c48\u6614\u591a\u5df4\uff09\u3002<\/p>\n

\n


<\/p>\n

\n
\n
<\/section>\n
\n

\u9500\u552e\u60c5\u51b5\u548c\u4e3b\u8981\u4ea7\u54c1<\/strong><\/span><\/p>\n<\/section>\n


<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

\u56fe1  2013-2017\u5e74\u7075\u5317\u603b\u6536\u5165\u67f1\u5f62\u56fe\uff08\u5355\u4f4d\uff1a\u767e\u4e07\u4e39\u9ea6\u514b\u6717\uff0c\u56fe\u7247\u6765\u6e90\u4e8e\u516c\u53f8\u5b98\u7f51\uff09<\/p>\n

 <\/strong><\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

\u56fe2  2013-2017\u5e74\u4e39\u9ea6\u7075\u5317\u635f\u76ca\uff08\u5355\u4f4d\uff1a\u767e\u4e07\u4e39\u9ea6\u514b\u6717\uff0c\u6570\u636e\u6765\u6e90\u4e8e\u516c\u53f8\u5b98\u7f51\uff09<\/p>\n


<\/p>\n

2017\u5e74\u5bf9\u4e8e\u7075\u5317\u6765\u8bf4\u662f\u6210\u529f\u7684\u4e00\u5e74\uff0c\u6536\u5165\u6301\u7eed\u7a33\u5b9a\u589e\u957f<\/span>\u30022017\u5e74\u4e39\u9ea6\u7075\u5317\u603b\u6536\u5165172.34\u4ebf\u4e39\u9ea6\u514b\u6717\uff08\u6298\u540826.11\u4ebf\u7f8e\u5143\uff09\uff0c\u6bd42016\u5e74\u589e\u957f10%\uff0c\u51c0\u5229\u6da6\u4e3a26.24\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u589e\u957f117%\u3002\u4e3b\u8981\u5f97\u76ca\u4e8eBrintellix\u00ae\/Trintellix\u00ae\u3001 Northera\u00ae\u3001Onfi\u00ae \u4ee5\u53caRexulti\u00ae\u9500\u552e\u6536\u5165\u7684\u5feb\u901f\u589e\u957f\u3002\uff082015\u5e74\u7814\u53d1\u8d39\u7528\u5305\u542bRexulti\u00ae\u4e0a\u5e02\u6240\u4ea7\u751f\u7684\u4ea7\u54c1\u6743\u5229\u51cf\u503c\uff09<\/span><\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

\u7eb5\u89c22013\u5e74\u81f32017\u5e74\u7075\u5317\u7684\u5e02\u573a\u8868\u73b0<\/span>\uff0c2014\u5e74\u603b\u6536\u5165\u51fa\u73b0\u4e0b\u964d\uff0c\u5f53\u5e74\u4e8f\u635f1.53\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u5230\u4e862015\u5e74\u867d\u7136\u603b\u7684\u6536\u5165\u4e0a\u5347\uff0c\u4f46\u8fd8\u662f\u4e8f\u635f\u4e8656.94\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u7075\u5317\u9677\u5165\u8d22\u52a1\u5371\u673a\u30022015\u5e74\u7075\u5317\u5f53\u5bb6\u54c1\u79cdCipralex\u00ae\/Lexapro\u00ae\u4ece2014\u5e74\u768446.47\u4ebf\u4e39\u9ea6\u514b\u6717\u8dcc\u81f325.91\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u6536\u5165\u4e0b\u964d44%\uff0c\u4eff\u5236\u836f\u7684\u7ade\u4e89\u5bf9\u7075\u5317\u7684\u4e1a\u7ee9\u9020\u6210\u4e86\u4e25\u91cd\u7684\u6253\u51fb\u3002<\/span>\u4ece2014\u5e74\u5f00\u59cb\u7075\u5317\u80a1\u4ef7\u4e00\u5ea6\u5927\u8dcc\u3002<\/p>\n

 <\/p>\n

\u8fd9\u4e2a\u65f6\u5019Kaare Schultz\u52a0\u5165\u7075\u5317\u516c\u53f8\u62c5\u4efbCEO\uff0c\u7b2c\u4e00\u6b65\u5c31\u662f\u88c1\u51cf\u4e8617%\u7684\u5458\u5de5\uff0c\u5927\u7ea61000\u4e2a\u5c97\u4f4d\u3002<\/span>\u63a5\u4e0b\u6765Kaare Schultz\u79ef\u6781\u52a9\u63a8\u7075\u5317\u4e00\u7cfb\u5217\u65b0\u4ea7\u54c1\u9500\u552e\uff0c\u5305\u62ecBrintellix\u00ae\/Trintellix\u00ae\u548cRexulti\u00ae\uff0c\u5e76\u5bf9\u516c\u53f8\u8fdb\u884c\u91cd\u7ec4\u30022016\u5e74\u516c\u53f8\u626d\u4e8f\u4e3a\u76c8\uff0c\u5229\u6da6\u8fbe\u523012.11\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c2017\u5e74\u5229\u6da6\u7ffb\u500d\u3002<\/span>\u4e0e\u6b64\u540c\u65f6\u80a1\u4ef7\u4e5f\u63d0\u9ad8\u4e863\u500d\u3002\u8fd9\u4f4d\u5584\u4e8e\u626d\u8f6c\u5c40\u9762\u7684CEO\u5982\u4eca\u5df2\u7ecf\u63a5\u53d7\u4e86Teva\u7684\u6a44\u6984\u679d\u30022017\u5e7411\u67081\u65e5\uff0c\u5df2\u7ecf\u62c5\u4efb\u7075\u531710\u5e74CFO\u7684Anders G\u00f6tzsche\u88ab\u4efb\u547d\u4e3a\u4e34\u65f6CEO\u517c\u6267\u884c\u526f\u603b\u88c1\u548cCFO\uff0c\u63a5\u7ba1\u7075\u5317\uff0c\u76f4\u5230\u65b0\u7684CEO\u5230\u4f4d\u3002<\/p>\n


<\/p>\n

\n
\n

\n

\u4e3b\u8981\u4ea7\u54c1\u7b80\u8981\u5206\u6790<\/strong><\/p>\n<\/h2>\n<\/section>\n<\/section>\n


<\/p>\n

\u6291\u90c1\u75c7\u6cbb\u7597\u836f\u7269<\/span><\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n


<\/p>\n

Cipralex\u00ae\uff08escitalopram\uff0c\u827e\u53f8\u897f\u915e\u666e\u5170\uff09<\/span>
<\/p>\n


<\/p>\n


<\/p>\n

Cipralex\u00ae\/Lexapro\u00ae\uff08\u827e\u53f8\u897f\u915e\u666e\u5170\uff09\u6700\u65e9\u4e8e2002\u5e74\u83b7\u7f8e\u56fdFDA\u6279\u51c6\uff0c<\/span>\u76ee\u524d\u5df2\u5728100\u591a\u4e2a\u56fd\u5bb6\u4e0a\u5e02\u3002\u7531\u4e8e\u8be5\u836f\u5bf9\u91cd\u5ea6\u6291\u90c1\u75c7\u7597\u6548\u663e\u8457\uff0c\u4e14\u5b89\u5168\u6027\u66f4\u597d\uff0c\u6210\u4e3a\u4e86\u4e16\u754c\u8303\u56f4\u5185\u6291\u90c1\u75c7\u6cbb\u7597\u7684\u4e00\u7ebf\u836f\u7269\u30022011\u5e74Cipralex\u00ae\/Lexapro\u00ae\u9500\u552e\u8fbe\u5230\u5cf0\u503c84.92\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u4f46\u7531\u4e8e\u4eff\u5236\u836f\u7ade\u4e89\uff0c2012\u5e74\u9500\u552e\u6536\u5165\u4e0b\u964d\u523064.02\u4ebf\u4e39\u9ea6\u514b\u6717\u3002\u4e4b\u540e\u4e00\u8def\u4e0b\u8dcc\u81f32015\u5e74\u768425.91\u4ebf\u4e39\u9ea6\u514b\u6717\u3002\u4f46\u622a\u81f32016\u5e74Cipralex\u00ae\u4e00\u76f4\u662f\u7075\u5317\u9500\u552e\u603b\u989d\u7684\u6700\u5927\u8d21\u732e\u8005\u3002<\/span><\/p>\n

 <\/p>\n

\u4e39\u9ea6\u7075\u5317\u7684\u8349\u9178\u827e\u53f8\u897f\u915e\u666e\u5170\u7247<\/span>2006\u5e74\u83b7\u4e2d\u56fd\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u5546\u54c1\u540d\u201c\u6765\u58eb\u666e\u201d\uff0c\u76ee\u524d\u5df2\u662f\u6211\u56fd\u6291\u90c1\u75c7\u6cbb\u7597\u7684\u91cd\u8981\u836f\u7269\u4e4b\u4e00\u3002<\/span><\/p>\n

 <\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

Brintellix\u00ae\/Trintellix\u00ae\uff08vortioxetin\uff0c\u4f0f\u786b\u897f\u6c40\uff09<\/p>\n


<\/p>\n


<\/p>\n

Brintellix\u00ae\/Trintellix\u00ae\u4e8e2013\u5e7410\u6708\u83b7\u7f8e\u56fdFDA\u6279\u51c6\uff0c2013\u5e7412\u6708\u83b7EMA\u6279\u51c6\u30022014\u5e74\u521d\uff0c\u7075\u5317\u4e0e\u5176\u5408\u4f5c\u4f19\u4f34\u6b66\u7530\u4e00\u8d77\u5728\u7f8e\u56fd\u63a8\u5e7f\u4e0a\u5e02\u3002\u81ea2014\u5e74\u8d77\uff0c\u8fd8\u5728\u591a\u4e2a\u6b27\u6d32\u548c\u56fd\u9645\u5e02\u573a\u4e0a\u5e02\u30022017\u5e74Brintellix\u00ae\/Trintellix\u00ae\u7684\u9500\u552e\u6536\u5165\u5df2\u8fbe\u5230\u4e3a16.62\u4ebf\u4e39\u9ea6\u514b\u6717\u3002<\/span><\/p>\n

 <\/span><\/p>\n

Brintellix\u00ae\/Trintellix\u00ae<\/span>\u662f5-\u7f9f\u8272\u80fa\uff085-HT\uff09\u518d\u6444\u53d6\u6291\u5236\u5242\uff0c\u4e5f\u662f5-HT1A\u53d7\u4f53\u6fc0\u52a8\u5242\uff0c5HT1B\u53d7\u4f53\u90e8\u5206\u6fc0\u52a8\u5242\u548c5-HT3,5-HT1D\u548c5-HT7\u53d7\u4f53\u62ee\u6297\u5242\u3002\u5b83\u88ab\u8ba4\u4e3a\u662f\u5177\u6709\u8fd9\u79cd\u836f\u6548\u5b66\u6d3b\u6027\u7ec4\u5408\u7684\u7b2c\u4e00\u79cd\u5316\u5408\u7269\u3002<\/span><\/p>\n

 <\/p>\n

\u4e39\u9ea6\u7075\u5317\u7684\u6c22\u6eb4\u9178\u4f0f\u786b\u897f\u6c40\u72472017\u5e74\u83b7\u4e2d\u56fdCFDA\u6279\u51c6\uff0c\u5546\u54c1\u540d\u201c\u5fc3\u60a6\u8fbe\u201d\uff0c\u76ee\u524d\u5df2\u4e0e\u56fd\u836f\u96c6\u56e2\u8fbe\u6210\u5408\u4f5c\u534f\u8bae\uff0c\u7531\u540e\u8005\u8d1f\u8d23\u5728\u56fd\u5185\u7684\u4e0a\u5e02\u63a8\u5e7f\u3002<\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

 <\/p>\n

Rexulti\u00ae \uff08brexpiprazole\uff0c\u4f9d\u5339\u54cc\u5511\uff09<\/p>\n


<\/p>\n


<\/p>\n

Rexulti\u00ae\u7531\u65e5\u672c\u5927\u51a2\u53d1\u73b0\u5e76\u7531\u5927\u51a2\u548c\u7075\u5317\u8054\u5408\u5f00\u53d1\u3002\u4f5c\u7528\u673a\u5236\u53ef\u80fd\u901a\u8fc7\u90e8\u5206\u6fc0\u6d3b\u4e94\u7f9f\u8272\u80fa5-HT1A\u53d7\u4f53\u548c\u591a\u5df4\u80faD2\u53d7\u4f53\u3001\u963b\u65ad\u4e94\u7f9f\u8272\u80fa5-HT2A\u53d7\u4f53\u800c\u53d1\u6325\u4f5c\u7528\u3002\u6b64\u5916\uff0cRexulti\u00ae\u5bf9\u53bb\u7532\u80be\u4e0a\u817a\u7d20\u03b11B\/2C\u53d7\u4f53\u8868\u73b0\u51fa\u9ad8\u4eb2\u548c\u529b\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8be5\u836f\u4e8e2015\u5e747\u6708\u83b7\u7f8e\u56fdFDA\u6279\u51c6\uff0c\u7528\u4e8e\u6210\u4eba\u6291\u90c1\u7684\u8f85\u52a9\u6cbb\u7597\u4ee5\u53ca\u6210\u4eba\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u6cbb\u7597\uff0c2015\u5e748\u6708\u4e0a\u5e02\u30022017\u5e74\u9500\u552e\u6536\u5165\u8fbe\u523012.47\u4ebf\u4e39\u9ea6\u514b\u6717\u3002<\/p>\n

 <\/span><\/strong><\/p>\n

\u766b\u75eb\u6cbb\u7597\u836f\u7269<\/span><\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n


<\/p>\n

Onfi\u00ae\uff08clobazam\uff0c\u6c2f\u5df4\u5360\uff09<\/p>\n


<\/p>\n


<\/p>\n

Onfi\u00ae\u4e3a2\u5c81\u53ca\u4ee5\u4e0a\u4eba\u7fa4lennox-gastaut\u7efc\u5408\u5f81\uff08LGS\uff09\u7684\u8f85\u52a9\u6cbb\u7597\u836f\u7269<\/span>\uff0c\u8be5\u836f\u4e3a\u957f\u6548\u82ef\u4e8c\u6c2e\u5353\u7c7b\u836f\u7269\uff0c\u5176\u9547\u9759\u526f\u4f5c\u7528\u5f88\u5c0f\uff0c\u66f4\u9002\u5408\u7528\u4e8e\u6210\u4eba\u766b\u75eb\u7684\u8f85\u52a9\u6cbb\u7597\u30022011\u5e7410\u6708\u83b7\u7f8e\u56fdFDA\u6279\u51c6\uff0c2012\u5e741\u6708\u5728\u7f8e\u56fd\u4e0a\u5e02\uff0c\u4e0a\u5e02\u5f53\u5e74\u9500\u552e\u91d1\u989d\u5c31\u8fbe\u52302.55\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u5360\u4e39\u9ea6\u7075\u5317\u5f53\u5e74\u6536\u5165\u76842%\uff0c\u4e4b\u540e\u9500\u552e\u91d1\u989d\u4fdd\u6301\u5feb\u901f\u589e\u957f\uff0c2017\u5e74Onfi\u00ae\u7684\u9500\u552e\u91d1\u989d\u8fbe\u523030.22\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u6210\u4e3a\u4e39\u9ea6\u7075\u5317\u9500\u552e\u6392\u540d\u7b2c\u4e00\u7684\u5f53\u5bb6\u4ea7\u54c1<\/span>\u3002Onfi\u00ae\u7684\u5e02\u573a\u4e3b\u8981\u5728\u5317\u7f8e\u5730\u533a\u3002<\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

 <\/p>\n

Sabril\u00ae\uff08vigabatrin\uff0c\u6c28\u5df1\u70ef\u9178\uff09<\/p>\n


<\/p>\n


<\/p>\n

Sabril\u00ae\u7528<\/span>\u4e8e\u96be\u6cbb\u6027\u590d\u6742\u90e8\u5206\u6027\u53d1\u4f5c\uff08rCPS\uff09\u548c\u5a74\u513f\u75c9\u631b\uff08IS\uff09\u7684\u6cbb\u7597\uff0c\u8be5\u836f\u4e3a\u03b3-\u6c28\u57fa\u4e01\u9178(GABA)\u7684\u7c7b\u4f3c\u7269\uff0c\u80fd\u7279\u5f02\u6027\u5730\u4e0eGABA\u6c28\u57fa\u8f6c\u79fb\u9176\u7ed3\u5408\uff0c\u5bfc\u81f4\u8111\u5185GABA\u6d53\u5ea6\u589e\u9ad8\uff0c\u4ece\u800c\u53d1\u6325\u6297\u766b\u75eb\u4f5c\u7528\u30022009\u5e74\u83b7\u7f8e\u56fdFDA\u6279\u51c6\uff0c\u7075\u5317\u901a\u8fc7\u6536\u8d2dOvationPharmaceuticals\u540e\u83b7\u5f97\u8be5\u836f\u7269\u7f8e\u56fd\u5e02\u573a\u3002Sabril\u00ae\u53ea\u5728\u5317\u7f8e\u5730\u533a\u9500\u552e\uff0c\u4e0a\u5e02\u4ee5\u6765\u4e00\u76f4\u5448\u589e\u957f\u8d8b\u52bf\uff0c2017\u5e74Sabril\u00ae\u7684\u9500\u552e\u6536\u5165\u8fbe\u523015.09\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c<\/span>\u5df2\u7ecf\u6210\u4e3a\u7075\u5317\u8d21\u732e\u9500\u552e\u6536\u5165\u7684\u4e3b\u8981\u4ea7\u54c1\u3002<\/span><\/p>\n

 <\/p>\n

\u7cbe\u795e\u5206\u88c2\u6cbb\u7597\u836f\u7269<\/span><\/p>\n


<\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n


<\/p>\n

AbilifyMaintena\u00ae\uff08aripiprazole\uff0c\u963f\u7acb\u54cc\u5511\uff09<\/p>\n


<\/p>\n


<\/p>\n

AbilifyMaintena\u00ae<\/span>\u4e3a\u7075\u5317\u4e0e\u5927\u51a2\u8054\u5408\u5f00\u53d1\u7684\u957f\u6548\u7248\u7cbe\u795e\u5206\u88c2\u75c7\u836f\u7269\uff0c\u662f\u9996\u4e2a\u6bcf\u6708\u4e00\u6b21\u808c\u5185\u6ce8\u5c04\u7684\u591a\u5df4\u80faD2\u53d7\u4f53\u90e8\u5206\u6fc0\u52a8\u5242\u30022013\u5e742\u6708\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\uff0c2013\u5e7411\u6708\u83b7\u5f97\u6b27\u6d32EMA\u6279\u51c6\uff0c\u81f3\u4eca\u5df2\u7ecf\u5728\u5168\u740340\u591a\u4e2a\u56fd\u5bb6\u4e0a\u5e02\u3002<\/span>2017\u5e747\u6708\u5728\u7f8e\u56fd\u548c\u52a0\u62ff\u5927\u6279\u51c6\u4e86\u6210\u4eba\u4e2d\u53cc\u76f8I\u578b\u75c7\u72b6\u7ef4\u6301\u6027\u5355\u836f\u6cbb\u7597\u7684\u9002\u5e94\u75c7\u30022017\u5e74\u9500\u552e\u6536\u5165\u5df2\u8fbe\u523013.31\u4ebf\u4e39\u9ea6\u514b\u6717\u3002<\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

 <\/p>\n

Rexulti\u00ae \uff08brexpiprazole\uff0c\u4f9d\u5339\u54cc\u5511\uff09<\/p>\n


<\/p>\n

\u524d\u6587\u63d0\u52302015\u5e74\u7075\u5317\u4e0e\u5927\u51a2\u4e00\u8d77\u5728\u7f8e\u56fd\u63a8\u51faRexulti\u00ae\uff0c\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86\u5176\u5728\u7cbe\u795e\u5206\u88c2\u75c7\u6cbb\u7597\u9886\u57df\u7684\u5730\u4f4d\u3002<\/span>2017\u5e74\uff0cRexulti\u00ae\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u52a0\u62ff\u5927\u548c\u6fb3\u5927\u5229\u4e9a\u7684\u7cbe\u795e\u5206\u88c2\u75c7\u30022017\u5e743\u6708\uff0cbrexpiprazole\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u9002\u5e94\u75c7\u5df2\u5728\u6b27\u6d32\u9012\u4ea4\u4e86\u4e0a\u5e02\u7533\u8bf7\uff0c\u5982\u679cEMA\u6279\u51c6\uff0c\u5219\u8be5\u4ea7\u54c1\u5728\u6b27\u76df\u7684\u54c1\u724c\u540d\u79f0\u5c06\u4e3aRxulti\u00ae\u3002<\/p>\n

 <\/p>\n

\u5176\u4ed6\u6cbb\u7597\u836f\u7269<\/span><\/p>\n


<\/p>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

Northera\u00ae\uff08droxidopa\uff0c\u5c48\u6614\u591a\u5df4\uff09<\/p>\n


<\/p>\n


<\/p>\n

Northera\u00ae<\/span>\u662f\u7531\u5927\u65e5\u672c\u4f4f\u53cb\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u79cd\u5408\u6210\u6c28\u57fa\u9178\u53bb\u7532\u80be\u4e0a\u817a\u7d20\u7684\u524d\u4f53<\/span>\uff0c\u9002\u7528\u4e8e\u6210\u5e74\u6709\u75c7\u72b6\u6027\u795e\u7ecf\u6e90\u6027\u4f53\u4f4d\u6027\u4f4e\u8840\u538b\u60a3\u8005\u6cbb\u7597\u539f\u53d1\u6027\u81ea\u4e3b\u795e\u7ecf\u6027\u8870\u7aed\uff08\u5e15\u91d1\u68ee\u6c0f\u75c5\uff0c\u591a\u7cfb\u7edf\u840e\u7f29\uff0c\u548c\u7eaf\u81ea\u4e3b\u795e\u7ecf\u8870\u7aed\uff09\u6240\u81f4\u4f53\u4f4d\u6027\u7729\u6655\uff0c\u5934\u6655\uff0c\u6216\u201c\u611f\u89c9\u773c\u524d\u6f06\u9ed1\u201d\u591a\u5df4\u80fa\u03b2-\u7f9f\u5316\u9176\u7f3a\u4e4f\u75c7\uff0c\u548c\u975e-\u7cd6\u5c3f\u75c5\u6027\u81ea\u4e3b\u795e\u7ecf\u75c5\u53d8\u3002<\/p>\n

 <\/p>\n

2006\u5e74ChelseaTherapeutics\u516c\u53f8\u83b7\u5f97\u8be5\u54c1\u79cd\u9664\u65e5\u672c\u3001\u97e9\u56fd\u3001\u4e2d\u56fd\u3001\u4e2d\u56fd\u53f0\u6e7e\u4ee5\u5916\u7684\u5e02\u573a\u6388\u6743\u30022014\u5e74\u7075\u5317\u6536\u8d2d\u4e86ChelseaTherapeutics International Ltd\uff0c\u5e76\u56e0\u6b64\u5c06Northera\u00ae\uff0c\u6536\u5165\u56ca\u4e2d\u3002\u8be5\u4ea7\u54c1\u4e8e2014\u5e74\u521d\u83b7\u5f97\u7f8e\u56fdFDA\u7684\u6279\u51c6\u3002\u7075\u5317\u4e8e2014\u5e749\u6708\u5728\u7f8e\u56fd\u63a8\u51fa\u8be5\u4ea7\u54c1\uff0c2017\u5e74\u9500\u552e\u989d\u8fbe\u523016.44\u4ebf\u4e39\u9ea6\u514b\u6717\u3002<\/span><\/p>\n


<\/p>\n

 \"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/p>\n

Xenazine\u00ae\uff08tetrabenazine\uff0c\u4e01\u82ef\u90a3\u55ea\uff09<\/p>\n


<\/p>\n


<\/p>\n

Xenazine\u00ae\u7528\u4e8e\u6cbb\u7597\u4e0e\u4ea8\u5ef7\u987f\u75c5\u6709\u5173\u7684\u821e\u8e48\u75c7\u3002<\/span>2008\u5e74\u88ab\u7f8e\u56fdFDA\u6279\u51c6\u30022015\u5e74\u8fbe\u5230\u9500\u552e\u5cf0\u503c22.01\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c2016\u5e74\u5f00\u59cb\u4e0b\u964d\uff0c2017\u5e74\u9500\u552e\u989d\u4e3a10.49\u4ebf\u4e39\u9ea6\u514b\u6717\uff0c\u6bd42016\u5e74\u4e0b\u964d\u4e8633%\u3002Xenazine\u00ae\u7684\u4e3b\u8981\u5e02\u573a\u5728\u5317\u7f8e\u5730\u533a\uff0cXenazine\u00ae\u9500\u552e\u6536\u5165\u7684\u4e0b\u964d\u76f4\u63a5\u5f71\u54cd\u7740\u5317\u7f8e\u7684\u5e02\u573a\u6536\u5165\uff0c<\/span>\u597d\u5728\u5317\u7f8e\u5730\u533a\u7531\u4e8eBrintellix\u00ae\/Trintellix\u00ae\uff0cNorthera\u00ae\uff0cOnfi\u00ae\u548cRexulti\u00ae\u9500\u552e\u6536\u5165\u7684\u5feb\u901f\u4e0a\u5347\uff0c\u62b5\u6d88\u4e86Xenazine\u00ae\u9500\u552e\u6536\u5165\u7684\u4e0b\u964d\u30022017\u5e74\u5317\u7f8e\u5730\u533a\u6536\u5165\u5360\u603b\u6536\u5165\u768463\uff05\uff08\u4e0d\u5305\u62ec\u201c\u5176\u4ed6\u6536\u5165\u201d\uff09\uff0c\u8fd8\u9ad8\u4e8e2016\u5e74\u5317\u7f8e\u5730\u533a\u6536\u5165\u5360\u603b\u6536\u5165\u768460\uff05\u4efd\u989d\u3002<\/p>\n

\n


<\/p>\n

\n
\n
<\/section>\n
\n

\u7814\u53d1\u7ba1\u7ebf\u4ea7\u54c1<\/strong><\/span><\/p>\n<\/section>\n


<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"
<\/p>\n

2017\u5e742\u6708Idalopirdine\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5931\u8d25\uff1b2017\u5e745\u6708\u5ba3\u5e03Brexpiprazole\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684\u4e24\u4e2aIII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5931\u8d25\uff0c\u4f462017\u5e7411\u6708\u4efd\uff0c\u7075\u5317\u5f00\u59cb\u4e86Brexpiprazole\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684\u7b2c3\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\n


<\/p>\n

\n
\n
<\/section>\n
\n

\u7ed3\u8bed<\/strong><\/span><\/p>\n<\/section>\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\u7075\u5317\u9009\u62e9\u4e13\u6ce8\u4e8e\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u836f\u7269\u7684\u5f00\u53d1<\/span>\uff0c\u81f3\u4eca\u5df2\u7ecf\u4e3a\u5168\u7403\u6570\u767e\u4e07\u60a3\u8005\u5e26\u6765\u4e86\u6cbb\u7597\u9009\u62e9\u65b9\u6848\uff0c\u540c\u65f6\u81ea\u5df1\u4e5f\u5728\u9010\u6e10\u53d1\u5c55\u58ee\u5927\u3002\u867d\u7136\u76ee\u524d\u7075\u5317\u4f53\u91cf\u8fd8\u4e0d\u8db3\u4ee5\u4e0e\u90a3\u4e9b\u8d85\u7ea7\u8de8\u56fd\u5de8\u5934\u516c\u53f8\u76f8\u6bd4\u62df\uff0c\u4f46\u662f\u5176\u4e13\u4e1a\u5316\u7684\u7279\u8272\u4e5f\u5df2\u7ecf\u4f7f\u5176\u95fb\u540d\u4e8e\u4e16\uff0c\u6240\u8c13\u4e1a\u4e0d\u5728\u5927\uff0c\u5728\u4e8e\u4e13\uff0c<\/span>\u60f3\u5fc5\u7528\u6765\u5f62\u5bb9\u7075\u5317\u518d\u5408\u9002\u4e0d\u8fc7\u4e86\u3002<\/p>\n

 <\/p>\n

\u5728\u7ecf\u5386\u4e86\u7531\u4e8e\u533b\u7597\u6539\u9769\u7684\u6301\u7eed\u538b\u529b\u4ee5\u53ca\u4e13\u5229\u60ac\u5d16\u7684\u5f71\u54cd\u9677\u5165\u8d22\u52a1\u5371\u673a\uff0c\u540e\u56e0\u8058\u5f97\u62e5\u6709\u4f18\u79c0\u80fd\u529b\u7684\u9886\u5bfc\u8005\u4ee5\u53ca\u65b0\u4ea7\u54c1\u53ca\u65f6\u4e0a\u5e02\u626d\u8f6c\u5c40\u9762\u540e\uff0c<\/span>2017\u5e74\u7075\u5317\u6536\u5165\u7a33\u5b9a\u589e\u957f\uff0c\u5229\u6da6\u7ffb\u500d\u3002<\/span>\u4e0e\u6b64\u540c\u65f6\uff0c\u53c8\u51fa\u73b0\u4e86\u9ad8\u5c42\u7ba1\u7406\u53d8\u66f4\uff0c\u4e24\u4e2a\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u9879\u76ee\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5931\u8d25\u7684\u8d1f\u9762\u4fe1\u606f\u3002\u89c2\u5176\u540e\u7eed\u7814\u53d1\u7ba1\u7ebf\uff0cII\u671f\u53ca\u4ee5\u540e\u5728\u7814\u9879\u76ee\u4e0d\u591a\uff0c\u8fd9\u4e5f\u4e0e\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u65b0\u836f\u5f00\u53d1\u5931\u8d25\u7387\u4ee5\u53ca\u6210\u672c\u53cc\u9ad8\u7684\u73b0\u72b6\u6709\u4e00\u5b9a\u5173\u7cfb\uff0c\u8fd9\u6761\u8def\u4e00\u76f4\u4ee5\u6765\u90fd\u662f\u8def\u8270\u4e14\u957f\uff0c\u6211\u4eec\u656c\u4f69\u7075\u5317\u7684\u52c7\u6c14\u548c\u62c5\u5f53\uff0c\u795d\u613f\u8fd9\u5bb6\u4ee5\u4e13\u4e1a\u5316\u95fb\u540d\u81f4\u529b\u4e8e\u4e3a\u4eba\u7c7b\u89e3\u51b3\u7cbe\u795e\u548c\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u767e\u5e74\u836f\u4f01\u8d8a\u8d70\u8d8a\u597d\uff01<\/span><\/p>\n

 <\/p>\n

 <\/span><\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong>
1<\/span>\u3001<\/span>Lundbeck<\/span>\u5b98\u7f51\uff1a<\/span>http:\/\/www.lundbeck.com\/global<\/span>\uff1b<\/span>
2<\/span>\u3001<\/span>Wikipedia<\/span>\uff1a<\/span>https:\/\/en.wikipedia.org\/wiki\/Lundbeck<\/span><\/p>\n


<\/p>\n

——<\/span>END<\/strong><\/span>——<\/span>
<\/p>\n


<\/p>\n

\n
\n

\u5f81\u7a3f\u542f\u4e8b<\/a>
<\/span><\/strong><\/p>\n


<\/p>\n

\u540c\u5199\u610f\u8bba\u575b\uff1a<\/span><\/strong><\/p>\n

\n

1.\u7b2c91\u671f\u8bba\u575b\u4e28FDA\u4e13\u5bb6\u56e2\u9886\u822a\u65b0\u836f\u4e2d\u7f8e\u53cc\u62a5\u4e4b\u8def<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"<\/span><\/a><\/p>\n

\"\u4e1a\u4e0d\u5728\u5927\uff0c\u4e13\u5219\u5f3a------\u767e\u5e74\u836f\u4f01\u4e39\u9ea6\u7075\u5317\"
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