{"id":96547,"date":"2019-03-05T00:00:50","date_gmt":"2019-05-17T08:01:58","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/96547\/"},"modified":"2019-05-17T16:02:00","modified_gmt":"2019-05-17T08:02:00","slug":"f439f9ca79","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/96547\/","title":{"rendered":"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"__bg_gif\"         width=\"auto\" style=\"white-space: normal;text-align: center;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;z-index: -1;cursor: pointer;font-size: 14px;line-height: 22.4px;width: 558px;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/4-1558080118.jpeg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p>\u3000\u3000\u4e16\u754c\u4e0a\u6709\u6210\u5343\u4e0a\u4e07\u79cd\u7b49\u5f85\uff0c\u6765\u65e5\u53ef\u671f\u65e0\u7591\u662f\u6700\u597d\u7684\u4e00\u79cd\u3002\u5bf9\u4e8e\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u800c\u8a00\uff0c\u751f\u547d\u7684\u65e0\u5e38\u5145\u6ee1\u7a81\u7136\u4e0e\u9057\u61be\uff0c\u4f46\u662f\uff0c\u60a3\u8005\u5bf9\u56fd\u4ea7PD-1\u6291\u5236\u5242\u201c\u6551\u547d\u836f\u201d\u6b63\u5f0f\u5904\u65b9\u4e0a\u5e02\u7684\u6bb7\u5207\u671f\u76fc\uff0c\u5219\u662f\u6297\u51fb\u75c5\u9b54\u7684\u5e0c\u671b\u4e4b\u7a97\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u30002\u670826\u65e5\uff0c\u60a3\u8005\u53e3\u4e2d\u7684\u201c\u6551\u547d\u836f\u201d\u2014\u2014\u4e2d\u56fd\u9996\u4e2a\u81ea\u7814\u6297PD-1\u5355\u6297\u201c\u62d3\u76ca\u201d\uff0c\u5728\u5317\u4eac\u5f00\u51fa\u7b2c\u4e00\u5f20\u5904\u65b9\uff0c\u968f\u5373\u5ba3\u544a\u9762\u5411\u5168\u56fd30\u4e2a\u7701\u5e02\u517151\u5ea7\u57ce\u5e02\u542f\u52a8\u9500\u552e\u3002\u81ea\u6b64\uff0c\u541b\u5b9e\u751f\u7269\u6b63\u5f0f\u62c5\u8d1f\u8d77\u201c\u4e3a\u60a3\u8005\u63d0\u4f9b\u6548\u679c\u66f4\u597d\u3001\u82b1\u8d39\u66f4\u4f4e\u7684\u6cbb\u7597\u9009\u62e9\u201d\u4ea7\u4e1a\u4f7f\u547d\uff0c\u7528\u9ad8\u8d28\u91cf\u3001\u9ad8\u6027\u4ef7\u6bd4\u7684\u521b\u65b0\u836f\u56de\u62a5\u4e2d\u56fd\u60a3\u8005\u5bb6\u5ead\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"letter-spacing: 0.544px;text-align: center;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;width: 212px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558080118.jpg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;color: rgb(79, 129, 189);\">\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u526f\u9662\u957f\u90ed\u519b\u6559\u6388\u4e3a\u60a3\u8005\u5f00\u51fa\u62d3\u76ca\u9996\u5f20\u5904\u65b9<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;color: rgb(79, 129, 189);\">\u3000<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;color: rgb(79, 129, 189);\"><img class=\"\"       style=\"letter-spacing: 0.544px;text-align: center;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;width: 194px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558080118.jpg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/>\u3000<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;color: rgb(79, 129, 189);\">\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u7684\u62a4\u58eb\u6b63\u51c6\u5907\u4e3a\u60a3\u8005\u6ce8\u5c04\u62d3\u76ca<\/span><\/p>\n<p>\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"     style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"border-left: 5px solid #ef7060;font-weight: bold;line-height: 32px;color: #666666;padding: 5px 10px;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u201c\u7b2c\u4e00\u9897\u539f\u5b50\u5f39\u201d<\/span><\/strong><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u56fd\u4ea7PD-1\u6253\u7834\u8fdb\u53e3\u5784\u65ad<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p>\u3000\u3000<br  \/><\/p>\n<p>\u3000\u3000\u9ed1\u8272\u7d20\u7624\u662f\u4e00\u79cd\u6076\u6027\u7a0b\u5ea6\u6781\u9ad8\u7684\u76ae\u80a4\u80bf\u7624\uff0c\u8fdb\u5c55\u5feb\u3001\u6613\u8f6c\u79fb\uff0c\u4e25\u91cd\u5a01\u80c1\u60a3\u8005\u751f\u547d\u5065\u5eb7\uff0c\u60a3\u8005\u63a5\u53d7\u5316\u7597\u3001\u9776\u5411\u6cbb\u7597\u7b49\u5168\u8eab\u6027\u6cbb\u7597\u5931\u8d25\u540e\uff0c\u6ca1\u6709\u6709\u6548\u624b\u6bb5\u663e\u8457\u5ef6\u957f\u751f\u547d\uff0c\u76f4\u5230\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u51fa\u73b0\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u5982\u4eca\uff0c\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u9886\u57df\u7814\u7a76\u70ed\u70b9\u4e3b\u8981\u96c6\u4e2d\u5728\u6297\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u56e0\u5b501\uff08Programmed Death-1,PD-1\uff09\u53d7\u4f53\u7b49\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u4e0a\uff0c\u5b83\u548c\u4f20\u7edf\u7684\u5316\u7597\u548c\u9776\u5411\u6cbb\u7597\u4e0d\u540c\uff0c\u4e3b\u8981\u901a\u8fc7\u514b\u670d\u60a3\u8005\u4f53\u5185\u7684\u514d\u75ab\u6291\u5236\uff0c\u91cd\u65b0\u6fc0\u6d3b\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\u6765\u6740\u4f24\u80bf\u7624\uff0c\u662f\u4e00\u79cd\u5168\u65b0\u7684\u6297\u80bf\u7624\u6cbb\u7597\u7406\u5ff5\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u7531\u541b\u5b9e\u751f\u7269\u7814\u53d1\u7684\u65b0\u578b\u91cd\u7ec4\u4eba\u6e90\u5316\u6297PD-1\u5355\u6297\u62d3\u76ca\uff08\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff09\uff0c\u4e8e2018\u5e7412\u670817\u65e5\u83b7\u6279\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\uff0c\u8be5\u836f\u53ef\u901a\u8fc7\u5c01\u95edT\u6dcb\u5df4\u7ec6\u80de\u7684PD-1\uff0c\u963b\u65ad\u5176\u4e0e\u80bf\u7624\u7ec6\u80de\u8868\u9762PD-L1\u7ed3\u5408\uff0c\u89e3\u9664\u80bf\u7624\u7ec6\u80de\u5bf9\u514d\u75ab\u7ec6\u80de\u7684\u514d\u75ab\u6291\u5236\uff0c\u4f7f\u514d\u75ab\u7ec6\u80de\u91cd\u65b0\u53d1\u6325\u6297\u80bf\u7624\u7ec6\u80de\u514d\u75ab\u4f5c\u7528\u800c\u6740\u4f24\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u6b64\u524d\uff0c\u541b\u5b9e\u751f\u7269\u5df2\u7ecf\u516c\u5e03\u62d3\u76ca\u5b9a\u4ef7\uff1a7200\u5143\/240mg\uff08\u652f\uff09\uff0c\u51ed\u501f\u8fdc\u4f4e\u4e8e\u8fdb\u53e3\u540c\u7c7b\u836f\u7269\u7684\u201c\u4eb2\u6c11\u201d\u4ef7\u683c\uff0c\u7ed3\u5408\u6148\u5584\u8d60\u836f\u8ba1\u5212\uff0c\u5f88\u5927\u7a0b\u5ea6\u4e0a\u7f13\u89e3\u4e86\u836f\u7269\u53ef\u53ca\u6027\u95ee\u9898\uff0c\u8ba9\u66f4\u591a\u4e2d\u56fd\u60a3\u8005\u6709\u673a\u4f1a\u83b7\u5f97\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u673a\u4f1a\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u5f00\u51fa\u62d3\u76ca\u7b2c\u4e00\u5f20\u5904\u65b9\u7684\u90ed\u519b\u6559\u6388\u611f\u6168\uff0c\u516d\u5e74\u524d\u5728\u7f8e\u56fdASCO\u5927\u4f1a\u4e0a\u770b\u5230PD-1\u6297\u4f53\u7684\u795e\u5947\u7597\u6548\uff0c\u5fc3\u4e2d\u76fc\u671b\u7740\u8fd9\u6b3e\u836f\u7269\u4f55\u65f6\u80fd\u591f\u4ee5\u4f4e\u5ec9\u4ef7\u683c\u60e0\u53ca\u4e2d\u56fd\u767e\u59d3\u3002\u201c\u62d3\u76ca\u6210\u529f\u4e0a\u5e02\u7684\u610f\u4e49\u5982\u540c\u4e2d\u56fd\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u9886\u57df\u2018\u7b2c\u4e00\u9897\u539f\u5b50\u5f39\u2019\uff0c\u4ee5\u5b8c\u5168\u5ab2\u7f8e\u4e8e\u8fdb\u53e3\u540c\u7c7b\u4ea7\u54c1\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u9020\u798f\u4e2d\u56fd\u66f4\u5e7f\u6cdb\u7684\u9ed1\u8272\u7d20\u7624\u60a3\u8005\uff0c\u4e43\u81f3\u5176\u4ed6\u80bf\u7624\u60a3\u8005\u3002\u201d<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u5728\u4ea7\u4e1a\u5347\u7ea7\u548c\u76d1\u7ba1\u653f\u7b56\u6539\u9769\u5229\u597d\u4e4b\u4e0b\uff0c\u6b63\u662f\u4f9d\u9760\u541b\u5b9e\u751f\u7269\u5728\u521b\u65b0\u751f\u7269\u836f\u9886\u57df\u7684\u52aa\u529b\uff0c\u56fd\u4ea7PD-1\u5355\u6297\u6210\u529f\u6253\u7834\u4e86\u8de8\u56fd\u836f\u4f01\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u836f\u7269\u7684\u4ef7\u683c\u5784\u65ad\uff0c\u52a0\u901f\u52a9\u529b\u9ad8\u8d28\u91cf\u521b\u65b0\u836f\u7269\u60e0\u53ca\u60a3\u8005\u3002<\/p>\n<p>\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"     style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"border-left: 5px solid #ef7060;font-weight: bold;line-height: 32px;color: #666666;padding: 5px 10px;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u201c70\u5929\u627f\u8bfa\u201d<\/span><\/strong><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u751f\u4ea7\u4fdd\u969c\u5168\u529b\u4ee5\u8d74<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p>\u3000\u3000<br  \/><\/p>\n<p>\u3000\u3000\u201c\u5927\u4eba\u4e0d\u534e\u3001\u541b\u5b50\u52a1\u5b9e\u201d\u4ee3\u8868\u4e86\u4e00\u79cd\u7cbe\u795e\u4e0e\u8d23\u4efb,\u4e5f\u5f70\u663e\u4e86\u81ea\u4fe1\u548c\u80fd\u529b\u3002\u6309\u7167\u76d1\u7ba1\u653f\u7b56\u8981\u6c42\uff0c\u81ea2018\u5e7412\u670817\u65e5\u62d3\u76ca\u83b7\u6279\uff0c12\u670818\u65e5\u5f00\u59cb\u751f\u4ea7\u7684\u4ea7\u54c1\u624d\u5141\u8bb8\u7528\u4e8e\u5546\u4e1a\u5316\u9500\u552e\u3002\u541b\u5b9e\u751f\u7269\u9996\u5e2d\u8fd0\u8425\u5b98\u51af\u8f89\u5728\u63a5\u53d7\u5a92\u4f53\u4e13\u8bbf\u65f6\u66fe\u8868\u793a\uff1a\u201c\u4ece\u83b7\u6279\u4e4b\u65e5\u7b97\u8d77\uff0c\u7ecf\u8fc7\u751f\u4ea7\u3001\u8d28\u63a7\u3001\u653e\u884c\u4e00\u7cfb\u5217\u6d41\u7a0b\uff0c\u5230\u6700\u540e\u4e0a\u5e02\u5927\u6982\u9700\u8981\u4e24\u4e2a\u534a\u6708\u65f6\u95f4\uff0c\u9884\u8ba12\u6708\u5e95\u60a3\u8005\u5c31\u53ef\u4ee5\u7528\u4e0a\u62d3\u76ca\uff01\u201d<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u201c2\u6708\u5e95\u8ba9\u60a3\u8005\u7528\u4e0a\u62d3\u76ca\u201d\u662f\u541b\u5b9e\u751f\u7269\u5bf9\u81ea\u5df1\u7684\u97ad\u7b56\uff0c\u66f4\u662f\u4f01\u4e1a\u5bf9\u60a3\u8005\u7684\u627f\u8bfa\u3002\u622a\u81f3\u76ee\u524d\uff0c\u541b\u5b9e\u751f\u7269\u5b8c\u6210\u4e86\u591a\u6279\u539f\u6db2\u751f\u4ea7\u548c\u5236\u5242\u751f\u4ea7\uff0c\u5c3d\u53ef\u80fd\u7167\u987e\u5230\u66f4\u591a\u60a3\u8005\u7684\u7528\u836f\u9700\u6c42\uff0c\u6839\u636e\u82cf\u5dde\u5434\u6c5f\u7ecf\u6d4e\u6280\u672f\u5f00\u53d1\u533a\u751f\u4ea7\u57fa\u5730\u76843000L\u4ea7\u80fd\u89c4\u5212\uff0c\u53ef\u4ee5\u6ee1\u8db31.5\u4e07~1.8\u4e07\u540d\u60a3\u8005\u4e00\u5e74\u7684\u7528\u91cf\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u541b\u5b9e\u751f\u7269\u82cf\u5dde\u751f\u4ea7\u57fa\u5730\u8d1f\u8d23\u4eba\u6bb7\u4f83\u4ecb\u7ecd\uff0c\u5728\u62d3\u76ca\u6b63\u5f0f\u83b7\u6279\u540e\uff0c\u5168\u529b\u4ee5\u8d74\u505a\u597d\u751f\u4ea7\u4fdd\u969c\uff0c\u786e\u4fdd\u7b2c\u4e00\u65f6\u95f4\u628a\u201c\u6551\u547d\u836f\u201d\u9001\u5230\u60a3\u8005\u8eab\u8fb9\uff0c\u5c31\u662f\u5168\u4f53\u5458\u5de5\u5171\u540c\u7684\u613f\u671b\uff01\u201c\u516c\u53f8\u5728\u6625\u8282\u671f\u95f4\u4e5f\u5236\u5b9a\u4e86\u6392\u4ea7\u8ba1\u5212\uff0c\u5927\u90e8\u5206\u751f\u4ea7\u4eba\u5458\u575a\u5b88\u5c97\u4f4d\uff0c\u5927\u5bb6\u5bf9\u6b64\u90fd\u8868\u793a\u7406\u89e3\u548c\u652f\u6301\uff0c\u56e0\u4e3a\u6240\u6709\u4eba\u90fd\u89c9\u5f97\u5c3d\u5feb\u5c06\u62d3\u76ca\u9001\u8fbe\u60a3\u8005\u624b\u4e2d\u662f\u975e\u5e38\u6709\u610f\u4e49\u7684\u4e8b\u60c5\uff01\u201d<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4f01\u4e1a\u662f\u836f\u54c1\u8d28\u91cf\u5b89\u5168\u7684\u8d23\u4efb\u4e3b\u4f53\uff0c\u5bf9\u4ea7\u54c1\u8d1f\u8d23\u5c31\u662f\u5bf9\u60a3\u8005\u7684\u751f\u547d\u5b89\u5168\u8d1f\u8d23\u300270\u4e2a\u65e5\u65e5\u591c\u591c\uff0c\u6bb7\u4f83\u65e0\u6570\u6b21\u901a\u8fc7\u76d1\u63a7\u5c4f\u5e55\u89c2\u5bdf\u751f\u4ea7\u8f66\u95f4\u60c5\u51b5\uff0c\u8bb0\u4e0d\u6e05\u591a\u5c11\u56de\u7a7f\u8131\u5de5\u4f5c\u670d\uff0c\u76ee\u9001\u4e00\u4e2a\u4e2a6ML\u897f\u6797\u74f6\u8d70\u4e0b\u751f\u4ea7\u7ebf\u5165\u76d2\u88c5\u7bb1\uff0c\u7ec6\u80de\u57f9\u517b\u3001\u86cb\u767d\u7eaf\u5316\u3001\u704c\u88c5\u6bcf\u4e2a\u73af\u8282\u7684\u5173\u952e\u8282\u70b9\u5728\u4ed6\u5fc3\u4e2d\u90fd\u4e86\u7136\u4e8e\u80f8\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u201c\u62d3\u76ca\u5728\u524d\u671f\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u4e2d\u8bd5\u751f\u4ea7\u79ef\u7d2f\u4e86\u5927\u91cf\u7684\u751f\u4ea7\u3001\u8d28\u63a7\u3001\u653e\u884c\u7b49\u7ecf\u9a8c\uff0c\u56e0\u6b64\u5546\u4e1a\u6279\u6b21\u751f\u4ea7\u8fc7\u7a0b\u4e25\u683c\u9075\u5faaGMP\u89c4\u8303\uff0c\u5728\u5de5\u827a\u89c4\u7a0b\u3001SOP\u4ee5\u53ca\u8d28\u4fdd\u4f53\u7cfb\u4e0b\u719f\u7ec3\u64cd\u4f5c\u3002\u201d\u6bb7\u4f83\u544a\u8bc9\u8bb0\u8005\uff0c\u517c\u987e\u4e34\u5e8a\u7528\u836f\u9700\u6c42\u548c\u5546\u4e1a\u5316\u5e02\u573a\u7528\u836f\u9884\u4f30\uff0c\u751f\u4ea7\u56e2\u961f\u901a\u529b\u5408\u4f5c\uff0c\u9488\u5bf9\u836f\u54c1\u751f\u4ea7\u8fdb\u884c\u4e86\u5408\u7406\u89c4\u5212\u548c\u5206\u914d\uff0c\u6700\u7ec8\u6309\u65f6\u3001\u4fdd\u8d28\u3001\u4fdd\u91cf\u5730\u5b8c\u6210\u4e86\u751f\u4ea7\u4efb\u52a1\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4ece\u201c201901001\u201d\u4ea7\u54c1\u6279\u53f7\u6253\u4e0a\u70d9\u5370\uff0c\u5230\u6700\u540e\u4e00\u7bb1\u62d3\u76ca\u88c5\u5165\u51b7\u85cf\u8f66\uff0c\u9996\u6279\u5546\u4e1a\u5316\u4ea7\u54c1\u7684\u5e02\u573a\u5f81\u7a0b\uff0c\u81ea\u5434\u6c5f\u751f\u4ea7\u57fa\u5730\u8d77\u6b65\u9a76\u5411\u5168\u56fd\uff0c\u5404\u6e20\u9053\u51fa\u51fb\u5168\u9762\u5904\u65b9\u5f00\u552e\uff0c\u62d3\u76ca\u72b9\u5982\u6492\u843d\u795e\u5dde\u5927\u5730\u7684\u201c\u661f\u661f\u4e4b\u706b\u201d\uff0c\u70b9\u4eae\u4e86\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7684\u751f\u547d\u66d9\u5149\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558080119.jpg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;color: rgb(79, 129, 189);\">\u541b\u5b9e\u751f\u7269\u82cf\u5dde\u5434\u6c5f\u751f\u4ea7\u57fa\u5730<\/span><\/p>\n<p>\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"     style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"border-left: 5px solid #ef7060;font-weight: bold;line-height: 32px;color: #666666;padding: 5px 10px;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u201c\u591a\u4e2a\u4e2d\u56fd\u7b2c\u4e00\u201d<\/span><\/strong><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 18px;\"><strong style=\"caret-color: red;\"><span style=\"color: #ef7060;\">\u505a\u4e2d\u56fd\u4eba\u9700\u8981\u7684\u597d\u836f<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p>\u3000\u3000<br  \/><\/p>\n<p>\u3000\u3000\u62d3\u76ca\u7684\u6a2a\u7a7a\u51fa\u4e16\uff0c\u4ee3\u8868\u7740\u4e2d\u56fd\u9ad8\u6c34\u5e73\u521b\u65b0\u53d1\u56e2\u961f\u7684\u667a\u6167\u7ed3\u6676\uff0c\u5f70\u663e\u4e86\u5df2\u8dfb\u8eab\u56fd\u9645\u5b66\u672f\u821e\u53f0\u7684\u672c\u571f\u4e34\u5e8a\u7814\u7a76\u8005\u5162\u5162\u4e1a\u4e1a\u7684\u8d21\u732e\uff0c\u66f4\u662f\u201c\u5065\u5eb7\u4e2d\u56fd\u201d\u6218\u7565\u63a8\u8fdb\u3001\u56fd\u5bb6\u836f\u54c1\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u6539\u9769\u7684\u6210\u679c\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u65f6\u81f3\u4eca\u65e5\uff0c\u541b\u5b9e\u751f\u7269\u5df2\u6210\u4e3a\u4e2d\u56fd\u751f\u7269\u5236\u836f\u9886\u57df\u6781\u5177\u5f71\u54cd\u529b\u7684\u4f01\u4e1a\u4e4b\u4e00\uff0c\u7814\u53d1\u80fd\u529b\u5907\u53d7\u77a9\u76ee\uff0c\u516c\u53f8\u7814\u53d1\u7ba1\u7ebf\u5e03\u5c40\u54c1\u79cd\u5df2\u8fbe17\u9879\uff0c\u6cbb\u7597\u9886\u57df\u6db5\u76d6\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u3001\u708e\u75c7\u6216\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u4ee3\u8c22\u75be\u75c5\u3001\u6cbb\u7597\u795e\u7ecf\u6027\u75be\u75c5\u7b49\u91cd\u5927\u75be\u75c5\u9886\u57df\uff0c\u5176\u4e2d\uff0c\u201c\u6551\u547d\u836f\u201d\u62d3\u76ca\u7684\u7814\u53d1\u4ec5\u8017\u65f63\u5e74\u65f6\u95f4\u4fbf\u4ece\u5b9e\u9a8c\u5ba4\u8d70\u5165\u4e86\u60a3\u8005\u624b\u4e2d\uff0c\u5f15\u53d1\u4e1a\u754c\u60ca\u53f9\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u62d3\u76ca\u6210\u529f\u4e0a\u5e02\u9500\u552e\u65e0\u7591\u662f\u6211\u56fd\u751f\u7269\u5236\u836f\u4ea7\u4e1a\u53d1\u5c55\u7684\u91cd\u5927\u91cc\u7a0b\u7891\uff0c\u5e76\u521b\u9020\u4e86\u591a\u4e2a\u4e2d\u56fd\u7b2c\u4e00\uff1a2015\u5e7412\u6708\uff0c\u62d3\u76ca\u83b7\u5f97\u56fd\u5185\u7b2c\u4e00\u4e2a\u6297PD-1\u5355\u6297\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\uff1b2018\u5e743\u6708\uff0c\u62d3\u76ca\u6210\u4e3a\u56fd\u5185\u7b2c\u4e00\u4e2a\u88ab\u53d7\u7406\u65b0\u836f\u6ce8\u518c\u7684\u56fd\u4ea7\u6297PD-1\u5355\u6297\uff1b2018\u5e744\u6708\uff0c\u62d3\u76ca\u7684\u836f\u54c1\u6ce8\u518c\u7533\u8bf7\u88abCDE\u5217\u5165\u4f18\u5148\u5ba1\u8bc4\uff1b2018\u5e7412\u670817\u65e5\uff0c\u62d3\u76ca\u4f5c\u4e3a\u9996\u4e2a\u56fd\u4ea7\u6297PD-1\u5355\u6297\u83b7\u6279\u4e0a\u5e02\uff1b2019\u5e742\u670826\u65e5\uff0c\u62d3\u76ca\u5f00\u51fa\u9996\u5f20\u5904\u65b9\uff0c\u540c\u6b65\u542f\u52a8\u5168\u56fd\u9500\u552e\u2026\u2026\u91cd\u78c5\u8bb0\u5f55\u8fd8\u5728\u4e0d\u65ad\u5237\u65b0\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4f5c\u4e3a\u65b0\u578b\u91cd\u7ec4\u4eba\u6e90\u5316PD-1\u5355\u6297\uff0c\u62d3\u76ca\u5728\u5f00\u53d1\u9636\u6bb5\u7ecf\u5386\u91cd\u91cd\u7b5b\u9009\uff0c\u5176\u4e0e\u6cbb\u7597\u9776\u70b9\u7684\u4eb2\u548c\u529b\u548c\u7ed3\u5408\u7a33\u5b9a\u6027\u5747\u8fbe\u5230\u56fd\u9645\u9886\u5148\u6c34\u5e73\uff0c\u5728\u4f53\u5916\u548c\u4e34\u5e8a\u5b9e\u9a8c\u4e2d\u5c55\u73b0\u4e86\u5353\u8d8a\u7684\u6297\u80bf\u7624\u7597\u6548\uff0c\u4e34\u5e8a\u6570\u636e\u663e\u793a\u5176\u7597\u6548\u53ef\u9760\uff0c\u5b89\u5168\u6027\u826f\u597d\u3002<\/p>\n<p>\u3000\u3000<\/p>\n<p>\u3000\u3000\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u62d3\u76ca\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff0917.3%, 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style=\"text-align: left;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"letter-spacing: 0.544px;text-align: center;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;width: 428px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/5-1558080119.png\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/><\/p>\n<p style=\"text-align: left;\"><br  \/><\/p>\n<p style=\"text-align: left;\"><br  \/><\/p>\n<p style=\"white-space: normal;\"><strong style=\"color: rgb(62, 62, 62);font-size: 16px;max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"color: rgb(62, 62, 62);max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"color: rgb(62, 62, 62);max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u25a0\u5f20\u84dd\u98de<\/span><\/strong><\/span><\/strong><\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558080119.jpeg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558080119-1.jpg\" alt=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\" title=\"\u4ece\u5434\u6c5f\u5954\u5411\u5168\u56fd \u201c\u62d3\u76ca\u201d\u594f\u54cdPD-1\u836f\u7269\u56fd\u4ea7\u5316\u7b2c\u4e00\u4e50\u7ae0\"  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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":96548,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96547"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=96547"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96547\/revisions"}],"predecessor-version":[{"id":96556,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96547\/revisions\/96556"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/96548"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=96547"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=96547"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=96547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}