{"id":96726,"date":"2019-03-14T00:00:50","date_gmt":"2019-05-17T08:03:15","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/96726\/"},"modified":"2019-05-17T16:03:18","modified_gmt":"2019-05-17T08:03:18","slug":"03e10d2d61","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/96726\/","title":{"rendered":"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"white-space: normal;text-align: center;\"><img class=\"__bg_gif\"         width=\"auto\" style=\"letter-spacing: 0.544px;background-color: rgb(255, 255, 255);color: rgb(62, 62, 62);font-family: \u5fae\u8f6f\u96c5\u9ed1;z-index: -1;cursor: pointer;font-size: 14px;line-height: 22.4px;width: 558px;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/2-1558080195.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u4e0e\u5316\u5b66\u836f\u76f8\u6bd4\uff0c\u751f\u7269\u5236\u54c1\u5177\u6709\u751f\u4ea7\u5de5\u827a\u96be\u5ea6\u66f4\u9ad8\u3001\u751f\u7269\u5927\u5206\u5b50\u96be\u4ee5\u505a\u5230\u6279\u6b21\u4e4b\u95f4\u3001\u4ea7\u54c1\u4e4b\u95f4\u5b8c\u5168\u76f8\u540c\u7b49\u7279\u70b9\uff0c\u52a0\u4e4b\u4e0d\u5c11\u8fd9\u7c7b\u4ea7\u54c1\u6216\u5177\u6709\u653f\u7b56\u58c1\u5792\uff0c\u6216\u5177\u6709\u6d88\u8d39\u54c1\u724c\u5c5e\u6027\uff0c\u56e0\u6b64\u88ab\u8ba4\u4e3a\u662f\u201c\u5e26\u91cf\u91c7\u8d2d\u201d\u51b2\u51fb\u4e4b\u4e0b\u7684\u907f\u98ce\u6e2f\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u4ece\u5168\u56fd\u767e\u5e8a\u4ee5\u4e0a\u533b\u9662\u6570\u636e\u6765\u770b\uff0c2018\u5e741-9\u6708\u751f\u7269\u5236\u54c1\u5e02\u573a\u89c4\u6a21\u4e3a455.6\u4ebf\u5143\uff0c\u89c4\u6a21\u5360\u56fd\u5185\u603b\u4f53\u7528\u836f\u76848%\uff0c\u5e76\u4e14\u8fd1\u51e0\u5e74\u751f\u7269\u5236\u54c1\u5e02\u573a\u540c\u6bd4\u589e\u5e45\u5747\u9ad8\u4e8e\u6574\u4f53\u5e02\u573a\u589e\u5e45\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u8fd1\u5e74\u6765\uff0c\u968f\u7740\u56fd\u529b\u7684\u4e0d\u65ad\u63d0\u5347\uff0c\u6211\u56fd\u836f\u54c1\u7814\u53d1\u9886\u57df\u4e5f\u5728\u8ffd\u8d76\u5168\u7403\u524d\u6cbf\u3002\u901a\u8fc7\u6570\u636e\u5e93\u7edf\u8ba1\uff0c\u7b14\u8005\u53d1\u73b0\uff0cPD-1\/L1\u3001CD20\u3001HER2\u3001TNF-\u03b1\u662f\u6211\u56fd\u6700\u4e3a\u5173\u6ce8\u7684\u751f\u7269\u836f\u9776\u70b9\uff0c\u8fd94\u4e2a\u9776\u70b9\u4e5f\u4ea7\u751f\u4e86\u5f88\u591a\u201c\u91cd\u78c5\u70b8\u5f39\u201d\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u6bd4\u5982\uff0cPD-1\/L1\u7684\u201cO\u201d\u201cK\u201d\u836f\uff0c\u6297CD20\u5355\u6297\u836f\u7269\u7684\u4ee3\u8868\u5229\u59a5\u6614\u5355\u6297\uff08\u7f8e\u7f57\u534e\uff09,HER2\u9776\u70b9\u7684\u66f2\u59a5\u73e0\u5355\u6297\uff08\u8d6b\u8d5b\u6c40\uff09\u3002TNF-\u03b1\u5219\u662f\u4e34\u5e8a\u83b7\u6279\u548c\u4e34\u5e8a\u7814\u7a76\u6700\u591a\u7684\u9776\u70b9\u4e4b\u4e00\uff0c\u4e5f\u662f\u5355\u6297\u53d6\u5f97\u6700\u6210\u529f\u4e1a\u7ee9\u7684\u9776\u70b9\uff0c\u6709\u82f1\u592b\u5229\u897f\u5355\u6297\u3001\u963f\u8fbe\u6728\u5355\u6297\u3001\u6208\u5229\u6728\u5355\u6297\u548c\u8d5b\u59a5\u73e0\u5355\u62974\u4e2a\u91cd\u78c5\u70b8\u5f39\u7ea7\u54c1\u79cd\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u90a3\u4e48\uff0c\u8fd94\u4e2a\u9776\u70b9\u7684\u56fd\u5185\u7814\u53d1\u73b0\u72b6\u5982\u4f55\uff1f\u672a\u6765\u5e02\u573a\u7ade\u4e89\u683c\u5c40\u53c8\u5c06\u53d1\u751f\u600e\u6837\u7684\u53d8\u5316\uff1f<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"    style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-right: 3px;padding-left: 3px;\">\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<section class=\"135brush\" ><span style=\"line-height: 32px;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);font-size: 20px;\"><strong>&nbsp;1&nbsp;<\/strong><\/span><span style=\"font-size: 20px;line-height: 32px;color: rgb(255, 255, 255);\"><strong><span style=\"line-height: 32px;\">&nbsp;<\/span><\/strong><\/span><span style=\"color: rgb(239, 112, 96);line-height: 32px;font-size: 20px;\"><strong>PD-1\/L1\u9776\u70b9<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section  style=\"border-top: 1px solid rgb(239, 112, 96);width: 550px;float: left;\"><\/section>\n<section style=\"margin-top: -4px;width: 6px;height: 6px;border-radius: 100%;float: right;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section class=\"135brush\" style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<p><span style=\"color: rgb(79, 129, 189);font-size: 18px;\">2019\uff0c\u7fa4\u96c4\u5145\u5206\u7ade\u4e89\u5e74<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<\/section>\n<section style=\"width: 0px;height: 0px;clear: both;\"><\/section>\n<\/section>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u80bf\u7624\u514d\u75ab\u6cbb\u7597\uff08IO\uff09\u5df2\u6210\u4e3a\u665a\u671f\u6076\u6027\u80bf\u7624\u6cbb\u7597\u7684\u91cd\u8981\u624b\u6bb5\u4e4b\u4e00\u3002PD-1\/L1\u6297\u4f53\u836f\u4f5c\u4e3aIO\u4ee3\u8868\u836f\u7269\u4e4b\u4e00\uff0c\u5728\u665a\u671f\u6076\u6027\u80bf\u7624\u6cbb\u7597\u4e2d\u53d6\u5f97\u4e86\u5de8\u5927\u6210\u529f\uff0c\u76f8\u5173\u836f\u7269\u7684\u672a\u6765\u5e02\u573a\u7a7a\u95f4\u65e0\u7591\u5907\u53d7\u671f\u5f85\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u76ee\u524d\u7f8e\u56fd\u548c\u6211\u56fd\u4e0a\u5e02\u7684\u54c1\u79cd\u89c1\u88681\u3002BMS\u7684Opdivo\uff08\u6b27\u72c4\u6c83\uff0c\u7eb3\u6b66\u5229\u5c24\u5355\u6297\uff09\u4e8e2014\u5e747\u67084\u65e5\u5728\u65e5\u672c\u83b7\u6279\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u83b7\u5f97\u76d1\u7ba1\u673a\u6784\u6279\u51c6\u7684PD-1\u6291\u5236\u5242\uff1b2018\u5e746\u670815\u65e5\uff0cOpdivo\u5728\u4e2d\u56fd\u83b7\u4e0a\u5e02\u6279\u51c6\u3002\u9ed8\u6c99\u4e1c\u7684Keytruda\u4e8e2014\u5e749\u67084\u65e5\u88abFDA\u6279\u51c6\u7528\u4e8e\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\uff0c\u6210\u4e3aFDA\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u4e2aPD-1\u6291\u5236\u5242\uff1b2018\u5e747\u670825\u65e5\uff0cKeytruda\u5728\u4e2d\u56fd\u83b7\u4e0a\u5e02\u6279\u51c6\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/3-1558080195.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u56fd\u4ea7PD-1\u5355\u6297\u4ea6\u7d27\u9523\u5bc6\u9f13\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u30002018\u5e7412\u670817\u65e5\uff0c\u541b\u5b9e\u751f\u7269\u7684\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2(\u62d3\u76ca)\u83b7\u5f97\u6709\u6761\u4ef6\u4e0a\u5e02\u6279\u51c6\u3002\u8fd9\u662f\u6211\u56fd\u4f01\u4e1a\u72ec\u7acb\u7814\u53d1\u3001\u5177\u6709\u5b8c\u5168\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u751f\u7269\u521b\u65b0\u836f\uff0c\u4e5f\u662f\u56fd\u5185\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u6b3e\u56fd\u4ea7PD-1\u5355\u6297\uff0c\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u6807\u51c6\u6cbb\u7597\u5931\u8d25\u540e\u7684\u5c40\u90e8\u8fdb\u5c55\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u4fe1\u8fbe\u751f\u7269\u548c\u793c\u6765\u8054\u624b\u5f00\u53d1\u7684\u4fe1\u8fea\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u8fbe\u4f2f\u8212\uff09\u7d27\u968f\u5176\u540e\uff0c\u4e8e2018\u5e7412\u670827\u65e5\u83b7\u4e0a\u5e02\u6279\u51c6\uff0c\u9002\u5e94\u75c7\u662f\u81f3\u5c11\u7ecf\u8fc7\u4e8c\u7ebf\u7cfb\u7edf\u5316\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u7ecf\u5178\u578b\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u7684\u6cbb\u7597\u3002\u8fd9\u662f\u56fd\u5185\u6279\u51c6\u7684\u7b2c\u4e8c\u6b3e\u56fd\u4ea7PD-1\u5355\u6297\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u5728\u5168\u7403\u8303\u56f4\uff0cPD-1\u6700\u5feb\u4e0a\u5e02\u7684\u4e24\u4e2a\u91cd\u78c5\u836f\u2014\u2014\u201cO\u201d\u201cK\u201d\u836f\u7ade\u4e89\u6fc0\u70c8\u30022017\u5e74\uff0cOpdivo\u5168\u7403\u9500\u552e\u989d57.79\u4ebf\u7f8e\u5143\uff0c\u5168\u7403\u6392\u540d\u7b2c11\u4f4d\uff1b2018\u5e74\uff0cOpdivo\u5168\u7403\u9500\u552e\u989d\u7ee7\u7eed\u589e\u52a0\uff0c\u4e3a67.35\u4ebf\u7f8e\u5143\u30022017\u5e74Keytruda\u5168\u7403\u9500\u552e\u989d38.09\u4ebf\u7f8e\u5143\uff0c\u5168\u7403\u6392\u540d\u7b2c22\u4f4d\uff1b2018\u5e74\uff0cKeytruda\u5168\u7403\u9500\u552e\u989d\u5927\u5e45\u63d0\u5347\uff0c\u4e3a71.7\u4ebf\u7f8e\u5143\uff0c\u53cd\u8d85Opdivo\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u867d\u7136\u76ee\u524d\u56fd\u5185\u83b7\u6279\u7684PD-1\u9002\u5e94\u75c7\u90fd\u4ec5\u4e3a1\u4e2a\uff0c\u4f46\u56fd\u5185\u5728\u7814PD-1\/L1\u6709\u4e0d\u5c11\u8fbe\u5230\u4e34\u5e8aIII\u671f\u9636\u6bb5\u7684\u9879\u76ee\uff0c\u6d89\u53ca\u591a\u4e2a\u9002\u5e94\u75c7\uff08\u89c1\u88682\uff09\u3002\u968f\u7740\u66f4\u591a\u9002\u5e94\u75c7\u83b7\u6279\u4e0a\u5e02\uff0c2019\u5e74\u5c06\u6210\u4e3aPD-1\/L1\u5355\u6297\u8fd9\u4e00\u8fd1\u5e74\u6765\u5e02\u573a\u7a7a\u95f4\u548c\u9002\u5e94\u75c7\u6700\u4e3a\u5e7f\u6cdb\u7684\u5355\u6297\u54c1\u79cd\u5145\u5206\u7ade\u4e89\u7684\u4e00\u5e74\u3002\u6309\u7167\u5168\u56fd400\u4e07\u80bf\u7624\u60a3\u8005\u300110%\u4eba\u7fa4\u9002\u7528\u3001\u5355\u4eba\u5e74\u6d88\u8d39\u91d1\u989d10\u4e07\u7c97\u7565\u8ba1\u7b97\uff0cPD-1\/L1\u5177\u6709\u7ea6400\u4ebf\u5143\u7684\u5de8\u5927\u5e02\u573a\u6f5c\u529b\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/2-1558080196.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"    style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-right: 3px;padding-left: 3px;\">\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<section class=\"135brush\" ><span style=\"line-height: 32px;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);font-size: 20px;\"><strong>&nbsp;2&nbsp;<\/strong><\/span><span style=\"font-size: 20px;line-height: 32px;color: rgb(255, 255, 255);\"><strong><span style=\"line-height: 32px;\">&nbsp;<\/span><\/strong><\/span><span style=\"color: rgb(239, 112, 96);line-height: 32px;font-size: 20px;\"><strong>CD20\u9776\u70b9<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section  style=\"border-top: 1px solid rgb(239, 112, 96);width: 550px;float: left;\"><\/section>\n<section style=\"margin-top: -4px;width: 6px;height: 6px;border-radius: 100%;float: right;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section class=\"135brush\" style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<p><span style=\"color: rgb(79, 129, 189);font-size: 18px;\">\u56fd\u5185\u9996\u4eff\u836f\u83b7\u6279\uff0c\u6311\u6218\u7f8e\u7f57\u534e\u5784\u65ad\u5730\u4f4d<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<\/section>\n<section style=\"width: 0px;height: 0px;clear: both;\"><\/section>\n<\/section>\n<p style=\"white-space: normal;\">\u3000\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u30002019\u5e742\u670822\u65e5\uff0c\u4e0a\u6d77\u590d\u5b8f\u6c49\u9716\u7684\u5229\u59a5\u6614\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u6c49\u5229\u5eb7\uff09\u83b7\u4e0a\u5e02\u6279\u51c6\uff0c\u6210\u4e3a\u56fd\u5185\u83b7\u6279\u7684\u9996\u4e2a\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u4e3b\u8981\u7528\u4e8e\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u6cbb\u7597\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u6b64\u524d\u6211\u56fd\u4e0a\u5e02\u7684\u6297CD20\u5355\u6297\u53ea\u6709\u7f57\u6c0f\u7684\u7f8e\u7f57\u534e\uff0c\u56fd\u5185\u83b7\u6279\u9002\u5e94\u75c7\u662fCD20\u9633\u6027\u7684\u6ee4\u6ce1\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u5f25\u6f2b\u5927B\u7ec6\u80de\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u3002\u6839\u636eIQVIA\u6837\u672c\u533b\u9662\u7684\u9500\u552e\u6570\u636e\uff0c2017\u5e74\u6837\u672c\u533b\u9662\u7f8e\u7f57\u534e\u7684\u9500\u552e\u6536\u5165\u8fbe\u523017.3\u4ebf\u5143\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u6b64\u5916\uff0c\u76ee\u524d\u6709\u5341\u51e0\u5bb6\u836f\u4f01\u5728\u7814\u6297CD20\u5355\u6297\uff0c\u57fa\u672c\u90fd\u662f\u5229\u59a5\u6614\u7684\u751f\u7269\u7c7b\u4f3c\u836f\u3002\u5176\u4e2d\uff0c\u6211\u56fd\u6297CD20\u5355\u6297\u5728\u7814\u8fdb\u5165\u4e34\u5e8a\u2162\u671f\u9636\u6bb5\u7684\u4f01\u4e1a\u67098\u5bb6\uff0c\u5305\u62ec\u590d\u5b8f\u6c49\u9716\u3001\u4fe1\u8fbe\u751f\u7269\u3001\u6d77\u6b63\u836f\u4e1a\u7b49\u3002\u9884\u8ba1\u672a\u6765\u51e0\u5e74\u9646\u7eed\u4f1a\u6709\u4ea7\u54c1\u83b7\u6279\u4e0a\u5e02\uff0c\u4ece\u800c\u6253\u7834\u7f8e\u7f57\u534e\u7684\u5784\u65ad\u5c40\u9762\u3002\u540c\u65f6\uff0c\u7531\u4e8e\u56fd\u4ea7\u6297CD20\u5355\u6297\u7684\u4ef7\u683c\u4f18\u52bf\uff0c\u9884\u8ba1\u53ef\u63d0\u5347\u6297CD20\u5355\u6297\u5728\u975e\u970d\u5947\u91d1\u6c0f\u6dcb\u5df4\u7624\u9886\u57df\u7684\u6e17\u900f\u7387\uff0c\u672a\u6765\u5e02\u573a\u6709\u671b\u8fdb\u4e00\u6b65\u63d0\u5347\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/3-1558080196.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u5229\u59a5\u6614\u5c5e\u4e8e\u4eba\u9f20\u5d4c\u5408\u5355\u6297\uff0c\u6700\u65e9\u7531IDEC\uff08\u76ee\u524d\u5c5e\u4e8eBiogen\u516c\u53f8\uff09\u7814\u53d1\uff0c1997\u5e74\u5728\u7f8e\u56fd\u4e0a\u5e02\uff0c2017\u5e74\u5168\u7403\u9500\u552e\u989d\u8fbe\u523075.1\u4ebf\u7f8e\u5143\uff0c\u4f4d\u5217\u5168\u7403\u836f\u54c1\u9500\u91cf\u7b2c\u4e94\u3002\u5229\u59a5\u6614\u662f\u5168\u7403\u7b2c\u4e00\u4e2a\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u7684\u5355\u6297\uff0c\u76ee\u524d\u83b7FDA\u6279\u51c6\u7684\u9002\u5e94\u75c7\u5305\u62ec\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\u3001\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08CLL\uff09\u3001\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff08RA\uff09\u3001Wegener\u6c0f\u8089\u82bd\u80bf\uff08WG\uff09\u548c\u663e\u5fae\u955c\u591a\u8840\u7ba1\u708e\uff08MPA\uff09\u3002\u5229\u59a5\u6614\u5f00\u521b\u4e86\u6dcb\u5df4\u7624\u9776\u5411\u6cbb\u7597\u7684\u5148\u6cb3\uff0c\u5728\u5229\u59a5\u6614\u95ee\u4e16\u4e4b\u524d\uff0c\u4f20\u7edf\u5316\u7597\u836f\u7269\u4e00\u76f4\u662f\u6cbb\u7597\u6dcb\u5df4\u7624\u7684\u4e00\u7ebf\u6cbb\u7597\u65b9\u6848\u3002\u76ee\u524d\uff0c\u5229\u59a5\u6614\u4e0e\u5316\u7597\u836f\u7269CHOP\uff08\u73af\u78f7\u9170\u80fa\u3001\u591a\u67d4\u6bd4\u661f\u3001\u957f\u6625\u65b0\u78b1\u3001\u5f3a\u7684\u677e\uff09\u548cCVP\uff08\u73af\u78f7\u9170\u80fa\u3001\u957f\u6625\u65b0\u78b1\u3001\u5f3a\u7684\u677e\uff09\u7684\u8054\u7528\uff0c\u5206\u522b\u6210\u4e3a\u4e86\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u548c\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u6807\u51c6\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"    style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-right: 3px;padding-left: 3px;\">\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<section class=\"135brush\" ><span style=\"line-height: 32px;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);font-size: 20px;\"><strong>&nbsp;3&nbsp;<\/strong><\/span><span style=\"font-size: 20px;line-height: 32px;color: rgb(255, 255, 255);\"><strong><span style=\"line-height: 32px;\">&nbsp;<\/span><\/strong><\/span><span style=\"color: rgb(239, 112, 96);line-height: 32px;font-size: 20px;\"><strong>HER2\u9776\u70b9<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section  style=\"border-top: 1px solid rgb(239, 112, 96);width: 550px;float: left;\"><\/section>\n<section style=\"margin-top: -4px;width: 6px;height: 6px;border-radius: 100%;float: right;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section class=\"135brush\" style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<p><span style=\"color: rgb(79, 129, 189);font-size: 18px;\">\u8fdb\u53e3\u836f\u201c\u9738\u9053\u201d\uff0c\u671f\u5f85\u56fd\u5185\u66ff\u4ee3\u4ea7\u54c1<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<\/section>\n<section style=\"width: 0px;height: 0px;clear: both;\"><\/section>\n<\/section>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u8fd1\u5e74\u6765\uff0c\u9488\u5bf9HER2\u9776\u70b9\u8bbe\u8ba1\u7684\u836f\u7269\u4e00\u76f4\u662f\u7814\u7a76\u70ed\u95e8\u3002\u76ee\u524d\u5728\u56fd\u5185\u5df2\u4e0a\u5e02\u7684HER2\u9776\u5411\u836f\u7269\u4e3b\u8981\u6709\u66f2\u59a5\u73e0\u5355\u6297\u548c\u5e15\u59a5\u73e0\u5355\u6297\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u66f2\u59a5\u73e0\u5355\u6297\uff08\u8d6b\u8d5b\u6c40\uff092017\u5e74\u5168\u7403\u9500\u552e\u989d\u8d85\u8fc771.28\u4ebf\u7f8e\u5143\uff0c\u4f4d\u5217\u5168\u7403\u7b2c7\u4f4d\uff0c\u662f\u7f57\u6c0f\u7b2c\u4e8c\u7545\u9500\u7684\u836f\u7269\u3002\u8d6b\u8d5b\u6c40\u4e8e1998\u5e74\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c2012\u5e74\u5f00\u59cb\u5e74\u9500\u552e\u989d\u7a81\u783460\u4ebf\u7f8e\u5143\u3002\u7531\u4e8e2014\u5e74\u8d6b\u8d5b\u6c40\u5728\u6b27\u6d32\u548c\u65e5\u672c\u4e13\u5229\u5230\u671f\uff0c2015\u5e74\u4e13\u5229\u5728\u7f8e\u56fd\u5230\u671f\uff0c\u4ece2015\u5e74\u5f00\u59cb\u5168\u7403\u9500\u552e\u989d\u51fa\u73b0\u4e0b\u6ed1\u3002\u76ee\u524d\u5df2\u6709\u8bb8\u591a\u8d6b\u8d5b\u6c40\u751f\u7269\u7c7b\u4f3c\u836f\u5728\u7814\u53d1\u4e2d\uff0c\u9884\u8ba1\u672a\u6765\u51e0\u5e74\u8d6b\u8d5b\u6c40\u7684\u5168\u7403\u9500\u552e\u5c06\u51fa\u73b0\u8f83\u5927\u5e45\u5ea6\u4e0b\u964d\u3002\u800c\u5728\u4e2d\u56fd\u5e02\u573a\uff0c\u81ea2002\u5e74\u83b7\u51c6\u4e0a\u5e02\u4ee5\u6765\uff0c\u8d6b\u8d5b\u6c40\u4e00\u76f4\u4fdd\u6301\u7a33\u5b9a\u589e\u957f\uff0c2017\u5e74\u9500\u552e\u989d\u7ea617\u4ebf\u5143\u4eba\u6c11\u5e01\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u30002018\u5e7412\u670819\u65e5\uff0c\u5e15\u59a5\u73e0\u5355\u6297\uff08Perjeta\uff09\u83b7\u6279\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002\u5e15\u59a5\u73e0\u5355\u6297\u662f\u7f57\u6c0f\u7814\u53d1\u7684\u9488\u5bf9HER2\u9776\u70b9\u7684\u5355\u6297\u65b0\u836f\uff0c\u4e8e2012\u5e74\u83b7FDA\u6279\u51c6\u4e0a\u5e02\u3002\u5176\u53ef\u901a\u8fc7\u963b\u65adHER2\u53d7\u4f53\u7684\u4e8c\u805a\u5316\u800c\u963b\u6ede\u5176\u6fc0\u6d3b\uff0c\u4e0e\u914d\u4f53\u7684\u7ed3\u5408\u4f4d\u70b9\u548c\u66f2\u59a5\u73e0\u5355\u6297\u4e0d\u540c\u3002\u5e15\u59a5\u73e0\u5355\u6297\u88ab\u6279\u51c6\u4e0e\u66f2\u59a5\u73e0\u5355\u6297\u548c\u591a\u897f\u4ed6\u8d5b\u7b49\u8054\u5408\u7528\u4e8e\u672a\u7ecf\u6fc0\u7d20\u6cbb\u7597\u6216\u5316\u7597\u7b49\u65e2\u5f80\u6cbb\u7597\u7684HER2\u9633\u6027\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u30022017\u5e74Perjeta\u5168\u7403\u5e74\u9500\u552e\u989d\u4e3a22.32\u4ebf\u7f8e\u5143\uff0c\u4f4d\u5217\u5168\u7403\u7b2c50\u4f4d\uff0c\u73b0\u5df2\u6210\u4e3a\u4e73\u817a\u764c\u7684\u4e8c\u7ebf\u6cbb\u7597\u836f\u7269\uff0c\u6210\u4e3aFDA\u6279\u51c6\u7684\u9996\u4e2a\u4e73\u817a\u764c\u65b0\u8f85\u52a9\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u4e2d\u56fd\u662f\u4e73\u817a\u764c\u9ad8\u53d1\u56fd\uff0c\u60a3\u8005\u4f17\u591a\uff0cHER2\u5355\u6297\u5e02\u573a\u5de8\u5927\u3002\u56e0\u6b64\uff0c\u591a\u5bb6\u836f\u4f01\u81f4\u529b\u4e8e\u7814\u53d1\u8be5\u9776\u70b9\u836f\u7269\uff08\u8fdb\u5165\u2162\u671f\u4e34\u5e8a\u7684\u9879\u76ee\u89c1\u88684\uff09\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/4-1558080196.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u3000\u3000<\/p>\n<section class=\"_135editor\"    style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding-right: 3px;padding-left: 3px;\">\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<section class=\"135brush\" ><span style=\"line-height: 32px;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);font-size: 20px;\"><strong>&nbsp;4&nbsp;<\/strong><\/span><span style=\"font-size: 20px;line-height: 32px;color: rgb(255, 255, 255);\"><strong><span style=\"line-height: 32px;\">&nbsp;<\/span><\/strong><\/span><span style=\"color: rgb(239, 112, 96);line-height: 32px;font-size: 20px;\"><strong>TNF-\u03b1\u9776\u70b9<\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section  style=\"border-top: 1px solid rgb(239, 112, 96);width: 550px;float: left;\"><\/section>\n<section style=\"margin-top: -4px;width: 6px;height: 6px;border-radius: 100%;float: right;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<section class=\"135brush\" style=\"border-left: 1px solid rgb(239, 112, 96);\">\n<section style=\"padding: 3px 10px;\">\n<p><span style=\"color: rgb(79, 129, 189);font-size: 18px;\">\u8fdb\u53e3\u836f\u6c34\u571f\u4e0d\u670d\uff0c\u56fd\u5185\u7c7b\u4f3c\u836f\u6709\u4f5c\u4e3a<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-left: -3px;width: 6px;height: 6px;border-radius: 100%;color: rgb(255, 255, 255);background-color: rgb(239, 112, 96);\"><\/section>\n<\/section>\n<section style=\"width: 0px;height: 0px;clear: both;\"><\/section>\n<\/section>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000TNF-\u03b1\u9776\u70b9\u836f\u4ee5\u5355\u6297\u4e3a\u4e3b\uff0c\u76ee\u524d\u5df2\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u8fdb\u53e3\u836f\u5305\u62ec\u82f1\u592b\u5229\u897f\u5355\u6297\uff08\u7c7b\u514b\uff09\u3001\u963f\u8fbe\u6728\u5355\u6297\uff08\u4fee\u7f8e\u4e50\uff09\u3001\u6208\u5229\u6728\u5355\u6297\uff08Simponi\uff09\u548c\u4f9d\u90a3\u897f\u666e\uff08\u6069\u5229\uff09\uff0c\u9002\u5e94\u75c7\u4ee5\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u4e3a\u4e3b\uff08\u89c1\u88685\uff09\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/9-1558080197.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u4fee\u7f8e\u4e50\u548cSimponi\u662f\u5168\u4eba\u6e90\u5316\u5355\u6297\u4ea7\u54c1\uff0c\u4fee\u7f8e\u4e50\u4e5f\u662f\u5168\u7403\u7b2c\u4e00\u4e2a\u4e0a\u5e02\u7684\u5168\u4eba\u6e90\u5355\u6297\u836f\u54c1\u3002\u7c7b\u514b\u662f\u5d4c\u5408\u578b\u5355\u6297\uff0c\u7531\u4eba\u6297\u4f53\u7684\u6052\u5b9a\u533a\u57df\u548c\u9f20\u6e90\u6297\u4f53\u7684\u53ef\u53d8\u6297\u4f53\u5ac1\u63a5\u800c\u6210\u3002Cimzia\u662f\u805a\u4e59\u4e8c\u9187\u5316\uff08PEGylation\uff0cPEG\uff09\u7684\u4eba\u6e90\u5316\u6297\u539f\u7ed3\u5408\u7247\u6bb5\uff08\u5df2\u53d7\u7406\uff0c\u672a\u5728\u56fd\u5185\u4e0a\u5e02\uff09\u3002\u6069\u5229\u5219\u662f\u4e00\u79cd\u878d\u5408\u86cb\u767d\uff0c\u901a\u8fc7\u91cd\u7ec4DNA\u6280\u672f\uff0c\u878d\u5408TNF\u53d7\u4f53\u548c\u4eba\u6297\u4f53\u7684\u6052\u5b9a\u533a\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u9664\u4e86\u4e0a\u8ff04\u4e2a\u5df2\u5728\u6211\u56fd\u4e0a\u5e02\u7684\u8fdb\u53e3TNF-\u03b1\u5355\u6297\uff0c\u672c\u571f\u4f01\u4e1a\u81ea\u4e3b\u7814\u53d1\u5e76\u5df2\u4e0a\u5e02\u7684\u6709\u4e09\u751f\u56fd\u5065\u7684\u76ca\u8d5b\u666e\u3001\u8d5b\u91d1\u751f\u7269\u7684\u5f3a\u514b\u548c\u6d77\u6b63\u836f\u4e1a\u7684\u5b89\u4f70\u8bfa\u3002\u8fd9\u4e09\u79cd\u751f\u7269\u836f\u5c5e\u4e8e\u878d\u5408\u86cb\u767d\uff0c\u901a\u7528\u540d\u90fd\u662f\u91cd\u7ec4\u4eba\u2161\u578b\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\u53d7\u4f53-\u6297\u4f53\u878d\u5408\u86cb\u767d\uff0c\u4e5f\u53ef\u4ee5\u8bf4\u90fd\u662f\u6069\u5229\u7684\u751f\u7269\u7c7b\u4f3c\u836f\u3002\u4e09\u4e2a\u56fd\u4ea7\u54c1\u79cd\u7684\u83b7\u6279\u9002\u5e94\u75c7\u5747\u4e3a\uff1a\u91cd\u5ea6\u6d3b\u52a8\u6027\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\uff1b18\u5c81\u53ca18\u5c81\u4ee5\u4e0a\u6210\u4eba\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u6591\u5757\u72b6\u94f6\u5c51\u75c5\uff1b\u6d3b\u52a8\u6027\u5f3a\u76f4\u6027\u810a\u67f1\u708e\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/4-1558080197.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u636eIQVIA\u5168\u56fd\u767e\u5e8a\u4ee5\u4e0a\u533b\u9662\u7edf\u8ba1\uff0c2017\u5e74\u76ca\u8d5b\u666e\u4efd\u989d\u6700\u5927\uff0c\u9500\u552e\u89c4\u6a21\u4e3a6.7\u4ebf\u5143\uff0c\u5b89\u4f70\u8bfa\u3001\u5f3a\u514b\u7684\u9500\u552e\u89c4\u6a21\u5206\u522b\u4e3a0.1\u4ebf\u5143\u30010.8\u4ebf\u5143\u3002\u53d7\u5230\u56fd\u4ea7\u54c1\u79cd\u7684\u51b2\u51fb\uff0c\u5168\u7403\u201c\u836f\u738b\u201d\u4fee\u7f8e\u4e50\uff08\u963f\u8fbe\u6728\u5355\u6297\uff092017\u5e74\u5728\u4e2d\u56fd\u9500\u552e\u989d\u4ec5\u4e3a0.3\u4ebf\u5143\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u5728\u7f8e\u56fd\u5f71\u54cd\u7684\u4eba\u7fa4\u5927\u7ea6\u6709130\u4e07\uff0c\u5728\u4e9a\u6d32\u4eba\u7fa4\u53d1\u75c5\u6bd4\u4f8b\u7565\u4f4e\u4e8e\u6b27\u7f8e\u4eba\u7fa4\uff0c\u60a3\u75c5\u6bd4\u4f8b\u57280.2%\uff5e0.6%\uff0c\u4f30\u8ba1\u6211\u56fd\u60a3\u75c5\u4eba\u7fa4\u5728500\u4e07\u4eba\u5de6\u53f3\uff0c\u6f5c\u5728\u5e02\u573a\u89c4\u6a21125\u4ebf\u5143\uff08\u5047\u8bbe5%\u7684\u4eba\u5c31\u8bca\u3001\u5e74\u6cbb\u7597\u8d39\u75285\u4e07\u5143\uff09\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000\u6211\u56fd\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u7b49\u75be\u75c5\u5e02\u573a\u5c0f\u3001\u5c31\u8bca\u7387\u4f4e\u7684\u4e3b\u8981\u539f\u56e0\uff1a\u4e00\u662f\u6211\u56fd\u7f3a\u5c11\u76f8\u5173\u79d1\u5ba4\uff0c\u5168\u56fd\u53ea\u6709400\u591a\u5bb6\u533b\u9662\u8bbe\u6709\u4e13\u95e8\u7684\u98ce\u6e7f\u514d\u75ab\u79d1\uff1b\u4e8c\u662f\u751f\u7269\u836f\u4ef7\u683c\u6602\u8d35\uff0c\u57282017\u7248\u56fd\u5bb6\u533b\u4fdd\u63a8\u51fa\u4e4b\u524d\uff0cTNF\u6291\u5236\u5242\u53ea\u8fdb\u5165\u4e86\u5c11\u6570\u51e0\u4e2a\u7701\u5e02\u533b\u4fdd\u3002<\/p>\n<p style=\"white-space: normal;\">\u3000\u3000<\/p>\n<p style=\"white-space: normal;\">\u3000\u30002017\u65b0\u7248\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u4e2d\uff0c\u91cd\u7ec4\u4eba\u2161\u578b\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\u53d7\u4f53-\u6297\u4f53\u878d\u5408\u86cb\u767d\u9996\u6b21\u88ab\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u4e59\u7c7b\uff0c\u5bf9\u56fd\u4ea7\u7684\u76ca\u8d5b\u666e\u3001\u5b89\u4f70\u8bfa\u548c\u5f3a\u514b\u90fd\u662f\u91cd\u5927\u5229\u597d\uff0c\u6709\u671b\u4eab\u53d7\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u8c03\u6574\u5e26\u6765\u7684\u653f\u7b56\u7ea2\u5229\uff0c\u4e0d\u4ec5\u62a2\u5360\u8fdb\u53e3TNF\u6291\u5236\u5242\u7684\u5e02\u573a\u4efd\u989d\uff0c\u540c\u65f6\u6709\u671b\u6269\u5927TNF\u6291\u5236\u5242\u7684\u5e02\u573a\u6e17\u900f\u7387\u3002<\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;\"><strong style=\"color: rgb(62, 62, 62);font-size: 16px;max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"color: rgb(62, 62, 62);max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"color: rgb(62, 62, 62);max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(79, 129, 189);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u25a0\u7f16\u8f91 \u4f59\u5982\u747e<\/span><\/strong><\/span><\/strong><\/span><\/strong><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/10-1558080197.jpeg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/1-1558080197.jpg\" alt=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\" title=\"\u5e26\u91cf\u91c7\u8d2d\u907f\u98ce\u6e2f\uff01\u541b\u5b9e\u3001\u4fe1\u8fbe\u3001\u590d\u5b8f\u6c49\u9716\u2026\u8c01\u80fd\u62a2\u5360\u751f\u7269\u836f\u5148\u673a\uff1f\"  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u3000\u3000\u4e0e\u5316\u5b66\u836f\u76f8\u6bd4\uff0c\u751f\u7269\u5236\u54c1\u5177\u6709\u751f\u4ea7\u5de5\u827a\u96be\u5ea6\u66f4\u9ad8\u3001\u751f\u7269\u5927\u5206\u5b50\u96be\u4ee5\u505a\u5230\u6279\u6b21\u4e4b\u95f4\u3001\u4ea7\u54c1\u4e4b\u95f4\u5b8c\u5168\u76f8\u540c\u7b49\u7279\u70b9\uff0c\u52a0\u4e4b\u4e0d\u5c11\u8fd9 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":96727,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96726"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=96726"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96726\/revisions"}],"predecessor-version":[{"id":96737,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/96726\/revisions\/96737"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/96727"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=96726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=96726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=96726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}