{"id":98416,"date":"2019-03-25T00:00:50","date_gmt":"2019-05-17T08:14:32","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/98416\/"},"modified":"2019-05-17T16:14:35","modified_gmt":"2019-05-17T08:14:35","slug":"939894d1b3","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/98416\/","title":{"rendered":"\u7f8e\u56fdFDA \u6279\u51c6\u7684\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u4e0e\u7814\u53d1\u7b56\u7565"},"content":{"rendered":"
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\u901a\u8fc7\u5206\u6790<\/span>2001 \u5e741 \u67081 \u65e5\u20142017 \u5e745 \u670830 \u65e5\u671f\u95f4\u7f8e\u56fdFDA \u9996\u6b21\u6279\u51c6\u4e0a\u5e02\u768462 \u4e2a\u6297\u80bf\u7624\u9776\u5411\u65b0\u836f\u7684\u76f8\u5173\u6570\u636e\uff0c\u4ece\u9996<\/span>\u6b21\u4eba\u4f53\u8bd5\u9a8c\u9002\u5e94\u8bc1\u4eba\u7fa4\u7684\u9009\u62e9\u3001\u7814\u7a76\u8bbe\u8ba1\u3001\u836f\u653f\u7533\u62a5\u7b56\u75653 \u4e2a\u89d2\u5ea6\u8fdb\u884c\u56de\u987e\u6027\u5206\u6790\u3002\u901a\u8fc7\u5bf9\u4e0a\u8ff0\u6570\u636e\u7684\u5206<\/span>\u6790\uff0c\u603b\u7ed3\u51fa\u6297\u80bf\u7624\u9776\u5411\u65b0\u836f\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u8bbe\u8ba1\u4e0e\u4e34\u5e8a\u7814\u53d1\u7b56\u7565\u7684\u5171\u6027\u4e0e\u8d8b\u52bf\uff0c\u5e76\u5c31\u7814\u7a76\u7ed3\u679c\u5bf9\u4e8e\u4e2d\u56fd\u80bf\u7624\u521b<\/span>\u65b0\u836f\u7684\u65e9\u671f\u5f00\u53d1\u7684\u610f\u4e49\u505a\u9610\u8ff0\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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1. \u7814\u7a76\u8d44\u6599<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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2 \u7814\u7a76\u65b9\u6cd5<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7ed3\u679c<\/strong><\/p>\n<\/section>\n<\/section>\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n
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1. \u7eb3\u5165\u7814\u7a76\u836f\u7269\u6982\u8ff0<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u901a\u8fc7\u4e0a\u8ff0\u4fe1\u606f\u68c0\u7d22\u65b9\u6cd5\uff0c\u672c\u7814\u7a76\u5171\u7eb3\u516562 \u4e2a\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u3002<\/span><\/p>\n

\u2460 \u4ece\u7814\u7a76\u836f\u7269\u4e0a\u5e02\u65f6\u95f4\u5206\u6790\u3002\u5206<\/span>\u67902001\u20142016 \u5e74\u7f8e\u56fdFDA \u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u7684\u4e0a\u5e02<\/span>\u60c5\u51b5\uff0c\u6bcf4 \u5e74\u4e3a\u4e00\u4e2a\u65f6\u95f4\u8de8\u5ea6\u8fdb\u884c\u6570\u636e\u5206\u6790\uff0c\u603b\u4f53\u4e0a<\/span>\u5e02\u7684\u836f\u7269\u6570\u91cf\u5448\u73b0\u9012\u589e\u8d8b\u52bf\uff0c\u4ee5\u5c0f\u5206\u5b50\u9776\u5411\u836f\u7269\u6279<\/span>\u51c6\u4e0a\u5e02\u5c45\u591a\uff0c\u5927\u5206\u5b50\u5355\u6297\u836f\u7269\u5360\u5c11\u6570\uff0c\u5206\u522b\u536076%<\/span>( 47 \u4e2a) \u548c24% ( 15 \u4e2a) \u3002<\/span><\/p>\n

\u2461 \u4ece\u7eb3\u5165\u7814\u7a76\u836f\u7269\u7684\u9776<\/span>\u70b9\u5206\u6790\u3002\u7eb3\u5165\u7814\u7a76\u768462 \u4e2a\u836f\u7269\u4e2d\uff0c\u7814\u53d1\u548c\u4e0a\u5e02\u5360\u524d<\/span>3 \u4f4d\u7684\u9776\u70b9\u4e3a\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53( epidermal growth <\/span>factor receptor\uff0cEGF\uff32; 12\uff0e 9%) \u3001\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50<\/span>\u53d7\u4f53( vascular endothelial growth factor receptor\uff0cVEGF\uff32;<\/span>11. 3%) \u548c\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176( anaplastic lymphoma <\/span>kinase\uff0cALK) ( 6.5%) \u3002<\/span><\/p>\n

\u2462 \u4ece\u7eb3\u5165\u7814\u7a76\u836f\u7269\u9002\u5e94\u8bc1\u7c7b\u578b\u5206\u6790\u3002\u4ee5\u6cbb\u7597\u5b9e\u4f53\u7624\u7684\u6297\u80bf\u7624\u9776\u5411\u836f\u7269<\/span>\u4e3a\u4e3b( 60%) \uff0c\u8840\u6db2\u80bf\u7624\u836f\u7269\u76f8\u5bf9\u8f83\u5c11( 40%) \u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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2 \u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7eb3\u5165\u7814\u7a76\u9002\u5e94\u8bc1\u4eba\u7fa4\u7684\u9009\u62e9<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5171\u670935 \u4e2a\u836f\u7269\u7684\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7eb3\u5165\u7684\u53d7\u8bd5\u8005\u4e3a\u8fdb\u5c55\u6027\u5b9e\u4f53\u7624\u60a3\u8005\uff0c\u5360\u7eb3\u5165\u7814\u7a76\u7684\u836f\u7269\u603b\u6570\u7684<\/span>56. 45%\uff0c\u4e3a\u4e3b\u8981\u7684\u7814\u7a76\u9009\u62e9\u3002\u53d7\u8bd5\u8005\u4e3a\u8fdb\u5c55\u6027\u8840\u6db2<\/span>\u80bf\u7624\u60a3\u8005\u7684\u836f\u7269\u670916 \u4e2a( 25.81%) ; \u53d7\u8bd5\u8005\u4e3a\u8fdb\u5c55<\/span><\/p>\n

\u6027\u5b9e\u4f53\u7624\u53ca\u8840\u6db2\u80bf\u7624\u60a3\u8005\u7684\u836f\u7269\u67097 \u4e2a( 11.29%) ;\u53d7\u8bd5\u8005\u4e3a\u9650\u5b9a\u7279\u5b9a\u80bf\u7624\u7c7b\u578b\u60a3\u8005\u7684\u836f\u7269\u670920 \u4e2a<\/span>( 32. 26%) ; \u53d7\u8bd5\u8005\u4e3a\u5065\u5eb7\u5fd7\u613f\u8005\u7684\u836f\u7269\u67093 \u4e2a<\/span>( 4. 84%) \u3002\u5177\u4f53\u89c1\u56fe1\u3002<\/span><\/p>\n

\"\u7f8e\u56fdFDA<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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3 \u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7814\u7a76\u8bbe\u8ba1<\/span><\/strong><\/span>
<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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3.1 \u5242\u91cf\u9012\u589e\u65b9\u6cd5\u7684\u9009\u62e9<\/strong><\/p>\n

\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5242\u91cf\u9012\u589e\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u7684\u5728\u4e8e\u521d\u6b65\u63a2\u7d22\u836f\u7269\u7684\u5b89\u5168\u6027\u3001<\/span>\u786e\u5b9a\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u63a8\u8350\u5242\u91cf\u3002<\/span><\/p>\n

\u7eb3\u5165\u672c\u7814\u7a76\u768462<\/span>\u4e2a\u836f\u7269\u4e2d\uff0c\u8fd0\u7528\u57fa\u4e8e\u6cd5\u5219\u8bbe\u8ba1\u7684\u5171\u670948 \u4e2a\u836f\u7269<\/span>( 77. 42%) ; \u57fa\u4e8e\u6a21\u578b\u8bbe\u8ba1\u5171\u67096 \u4e2a\u836f\u7269( 9.68%) ;8 \u4e2a\u836f\u7269\u6ca1\u6709\u67e5\u627e\u5230\u76f8\u5e94\u7684\u4fe1\u606f\u3002<\/span><\/p>\n

\u57fa\u4e8e\u6cd5\u5219\u8bbe\u8ba1<\/span>\u4e2d\uff0c\u6807\u51c63 + 3 \u8bbe\u8ba1\u7684\u836f\u7269\u670941 \u4e2a( 66.13%) ; \u5feb\u901f<\/span>\u6ef4\u5b9a\u8bbe\u8ba1\u7684\u836f\u7269\u67095 \u4e2a( 8. 06%) \u3002\u57fa\u4e8e\u6a21\u578b\u8bbe\u8ba1\u7684\u836f\u7269\u67096 \u4e2a( 9. 68%) \uff0c\u4ee5\u4f7f\u7528\u8d1d\u53f6\u65af\u6a21\u578b\u7684\u8fde\u7eed<\/span>\u8bc4\u4f30\u65b9\u6cd5\u4e3a\u4e3b\u3002<\/span><\/p>\n

\u4ece\u6539\u826f\u7684\u5242\u91cf\u9012\u589e\u8bbe\u8ba1\u65b9\u6cd5( \u5982\u5feb<\/span>\u901f\u6ef4\u5b9a\u6cd5\u3001\u57fa\u4e8e\u6a21\u578b\u7684\u8bbe\u8ba1\u65b9\u6cd5) \u7684\u89d2\u5ea6\u5206\u6790\uff0c\u4ec5\u6709<\/span>12 \u4e2a\u836f\u7269\u91c7\u7528\u4e86\u6539\u826f\u7684\u5242\u91cf\u9012\u589e\u8bbe\u8ba1\u65b9\u6cd5\u3002\u5177\u4f53<\/span>\u89c1\u88681\u3002<\/span><\/p>\n

\"\u7f8e\u56fdFDA<\/p>\n

3.2 \u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027( dose-limiting toxicity\uff0cDLT)<\/strong><\/p>\n

\u7684\u754c\u5b9a\u4eceDLT \u5b9a\u4e49\u7684\u5185\u5bb9\u548c\u8bc4\u4f30\u65f6\u95f42 \u4e2a\u65b9\u9762\uff0c\u5bf9\u7eb3\u5165\u672c\u7814\u7a76\u7684\u6297\u80bf\u7624\u836f\u7269\u5728\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684<\/span>DLT \u5b9a\u4e49\u8fdb\u884c\u603b\u7ed3\u4e0e\u5206\u6790\uff0c\u8fdb\u4e00\u6b65\u6c47\u603b\u51fa\u6297\u80bf\u7624\u9776<\/span>\u5411\u836f\u7269\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6700\u5e38\u91c7\u7528\u7684DLT \u5b9a\u4e49\u3002<\/span><\/p>\n

\u7eb3\u5165\u7814\u7a76\u836f\u7269\u7684\u65e9\u671f\u8bd5\u9a8c\u4e2d\uff0cDLT \u76f8\u5173\u7684\u5b89\u5168\u6027\u8bc4\u4f30\u65f6\u95f4\u5747\u4e3a\u7ed9\u4e88\u53d7\u8bd5\u8005\u8bd5\u9a8c\u836f\u7269\u7684\u7b2c1 \u4e2a\u5468<\/span>\u671f\u3002<\/span><\/p>\n

\u672c\u90e8\u5206\u6c47\u603b\u9002\u5408\u8bc4\u4ef7\u6297\u80bf\u7624\u836f\u7269DLT \u7684\u5b9a\u4e49\uff0c<\/span>\u9664\u53bb17 \u4e2a\u836f\u7269\u672a\u5728\u76f8\u5173\u6587\u732e\u4e2d\u6536\u96c6\u5230DLT \u5b9a\u4e49\uff0c<\/span>\u5bf945 \u4e2a\u836f\u7269\u7684\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684DLT \u5b9a\u4e49\u8fdb\u884c\u6c47<\/span>\u603b\u3002<\/span>\u4e3b\u8981\u7684DLT \u5b9a\u4e49\u4e3a: <\/span><\/p>\n

\u2460 \u4efb\u4f553 \u7ea7\u53ca\u4ee5\u4e0a\u836f\u7269\u76f8<\/span>\u5173\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/span><\/p>\n

\u2461 3 \u7ea7\u4ee5\u4e0a\u4e0e\u8bd5\u9a8c\u836f\u7269\u76f8\u5173\u7684\u975e<\/span>\u8840\u6db2\u5b66\u6bd2\u6027\u3002<\/span><\/p>\n

\u2462 4 \u7ea7\u4ee5\u4e0a\u4e0e\u8bd5\u9a8c\u836f\u7269\u76f8\u5173\u7684\u8840\u6db2<\/span>\u5b66\u4e0d\u826f\u4e8b\u4ef6\u3002<\/span><\/p>\n

\u2463 4 \u7ea7\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\uff0c\u6301\u7eed\u65f6<\/span>\u95f4\u22657 d \u4e3a\u4e3b\u3002<\/span><\/p>\n

\u2464 \u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u4ee5\u4e25\u91cd\u7ea7\u522b\u4e3a4 \u7ea7<\/span>\u5360\u591a\u6570\uff0c\u6216\u22653 \u7ea7\u8840\u5c0f\u677f\u51cf\u5c11\u540c\u65f6\u4f34\u6709\u51fa\u8840\u3002<\/span><\/p>\n

\u2465 \u56e0<\/span>\u6cbb\u7597\u836f\u7269\u76f8\u5173\u7684\u6bd2\u6027\u53cd\u5e94\u5bfc\u81f4\u4e2d\u65ad\u7528\u836f\u81f3\u5c1114 d\uff0c<\/span>\u6216\u81f3\u5c11\u4e2d\u65ad7 d\u3002<\/span><\/p>\n

\u2466 \u8f93\u6db2\u53cd\u5e94\u76f8\u5173\u7684DLT \u5b9a\u4e49: \u9996<\/span>\u6b21\u8f93\u6ce8\u65e5\uff0c4 \u7ea7\u4e0e\u8f93\u6db2\u53cd\u5e94\u76f8\u5173\u7684\u53cd\u5e94\u4ee5\u53ca3 \u7ea7\u8f93<\/span>\u6db2\u53cd\u5e94\u540c\u65f6\u8f93\u6db2\u901f\u7387\u964d\u4f4e\u3001\u5242\u91cf\u4e2d\u65ad\u6216\u652f\u6301\u6027\u62a4\u7406<\/span>\u672a\u7f13\u89e3\u3002<\/span><\/p>\n

3.3 \u751f\u7269\u6807\u5fd7\u7269\u7684\u5e94\u7528<\/strong><\/p>\n

\u751f\u7269\u6807\u5fd7\u7269\u662f\u6307\u53ef\u4ee5\u6807\u8bb0\u7cfb\u7edf\u3001\u5668\u5b98\u3001\u7ec4\u7ec7\u3001\u7ec6\u80de\u53ca\u4e9a\u7ec6\u80de\u7ed3\u6784\u6216\u529f\u80fd\u6539\u53d8<\/span>\u6216\u53ef\u80fd\u53d1\u751f\u7684\u6539\u53d8\u7684\u751f\u5316\u6307\u6807\uff0c\u5177\u6709\u975e\u5e38\u5e7f\u6cdb\u7684\u7528<\/span>\u9014\u3002\u751f\u7269\u6807\u5fd7\u7269\u5206\u4e3a\u9884\u6d4b\u6027\u3001\u836f\u6548\u5b66\u3001\u9884\u540e\u6027\u4ee5\u53ca\u4ee3<\/span>\u7406\u6027\u751f\u7269\u6807\u5fd7\u7269\uff3b3\uff3d\u3002<\/span><\/p>\n

\u7eb3\u5165\u7814\u7a76\u768462 \u4e2a\u836f\u7269\u4e2d\uff0c\u9664\u53bb\u65e0\u6cd5\u83b7\u5f97\u76f8\u5e94\u4fe1\u606f\u76843 \u4e2a\u836f\u7269\uff0c\u6d89\u53ca\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u7684\u670947 \u4e2a\u836f\u7269<\/span>( 75.81%) \uff0c\u672a\u6d89\u53ca\u7684\u670915 \u4e2a\u836f\u7269( 24.19%) \u3002<\/span><\/p>\n

\u901a<\/span>\u8fc7\u5bf9\u9776\u6807\u6216\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\uff0c\u63a2\u7d22\u836f\u7269\u7684\u836f\u6548\u5b66\u7279<\/span>\u6027\uff0c\u4e3a\u5242\u91cf\u786e\u5b9a\u63d0\u4f9b\u4f9d\u636e\u3002\u6d89\u53ca\u68c0\u6d4b\u7684\u6837\u672c\u6709\u8840\u6837\u3001<\/span>\u80bf\u7624\u7ec4\u7ec7\u3001\u76ae\u80a4\u7ec4\u7ec7\uff0c\u6d89\u53ca\u836f\u7269\u7684\u4e2a\u6570\u5206\u522b\u4e3a27 \u4e2a<\/span>( 65. 9%) \u300114 \u4e2a( 34.1%) \u30015 \u4e2a( 12.2%) \u3002<\/span><\/p>\n

3. 4 \u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76<\/span><\/strong><\/p>\n

\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u4e0e\u4f20<\/span>\u7edf\u7684\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u67092 \u4e2a\u91cd\u8981\u7684\u4e0d\u540c\u4e4b\u5904\u3002\u7b2c\u4e00\u4e2a<\/span>\u4e0d\u540c\u4e4b\u5904\u662f\u62db\u52df\u53d7\u8bd5\u8005\u7684\u6807\u51c6\u4e0d\u540c\u3002<\/span><\/p>\n

\u5242\u91cf\u62d3\u5c55\u961f\u5217<\/span>\u7814\u7a76\u7eb3\u5165\u7684\u53d7\u8bd5\u8005\u5f88\u53ef\u80fd\u5c5e\u4e8e\u4e00\u4e2a\u66f4\u7a84\u3001\u5b9a\u4e49\u66f4\u660e<\/span>\u786e\u7684\u76ee\u6807\u60a3\u8005\u7c7b\u522b\uff0c\u4f8b\u5982\u4e3a\u7279\u5b9a\u7684\u75be\u75c5\u6216\u7ec4\u7ec7\u5b66\u961f<\/span>\u5217\u3002<\/span><\/p>\n

\u7b2c\u4e8c\u79cd\u5dee\u5f02\u5728\u4e8e\u76f8\u5173\u4fe1\u606f\u7684\u6536\u96c6\u76ee\u7684\u4e0d\u540c\u3002\u5242<\/span>\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u66f4\u591a\u5730\u4f1a\u5bf9\u7597\u6548\u6570\u636e\u548c\u9644\u52a0\u5b89\u5168\u6570<\/span>\u636e\u8fdb\u884c\u6536\u96c6\uff3b4\uff3d\u3002<\/span><\/p>\n

\u7eb3\u5165\u672c\u7814\u7a76\u768462 \u4e2a\u836f\u7269\u4e2d\uff0c\u6d89\u53ca\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u7684\u836f\u7269\u517122\u4e2a\uff0c\u672a\u6d89\u53ca\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u7684\u836f<\/span>\u7269\u517140 \u4e2a\u3002\u4ece\u6574\u4f53\u6765\u770b\uff0c\u672a\u6d89\u53ca\u62d3\u5c55\u961f\u5217\u7814\u7a76\u8005\u5c45<\/span>\u591a\u30022009 \u5e74\u4e4b\u524d\u4e0a\u5e02\u7684\u7eb3\u5165\u672c\u7814\u7a76\u7684\u836f\u7269\u5747\u672a\u5728<\/span>\u2160\u671f\u8bd5\u9a8c\u4e2d\u5f00\u5c55\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\uff0c\u4f46\u662f2009 \u5e74\u4ee5<\/span>\u540e\u4e0a\u5e02\u7684\u836f\u7269\u5f00\u59cb\u6709\u6d89\u53ca\uff0c\u540c\u65f6\u6709\u9010\u5e74\u5347\u9ad8\u7684\u8d8b\u52bf\uff0c<\/span>\u5177\u4f53\u89c1\u88682\u3002<\/span><\/p>\n

\"\u7f8e\u56fdFDA<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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4 \u836f\u653f\u7533\u62a5\u7b56\u7565
<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7f8e\u56fdFDA \u4e3b\u8981\u67094 \u79cd\u52a0\u5feb\u65b0\u836f\u5ba1\u8bc4\u5ba1\u6279\u7684\u9014\u5f84\uff0c\u5206\u522b\u4e3a\u5feb\u901f\u901a\u9053\u3001\u7a81\u7834\u6027\u7597\u6cd5\u3001\u52a0\u901f\u5ba1\u6279\u548c\u4f18\u5148<\/span>\u5ba1\u8bc4\u3002\u867d\u71364 \u79cd\u52a0\u5feb\u5ba1\u8bc4\u9014\u5f84\u7684\u8bc4\u5224\u6807\u51c6\u4e0d\u540c\uff0c\u4f46<\/span>\u540c\u4e00\u4e2a\u65b0\u836f\u5f80\u5f80\u53ef\u4ee5\u83b7\u5f97\u4e0d\u6b62\u4e00\u79cd\u52a0\u5feb\u65b9\u5f0f\uff3b5 \uff0d 6\uff3d\u3002<\/span><\/p>\n

\u5bf962 \u4e2a\u836f\u7269\u662f\u5426\u9996\u6b21\u6309\u7279\u6b8a\u7533\u62a5\u5f62\u5f0f\u7533\u62a5\u8fdb<\/span>\u884c\u6c47\u603b\uff0c\u5177\u4f53\u89c1\u56fe2\u3002<\/span><\/p>\n

\"\u7f8e\u56fdFDA<\/p>\n

62 \u4e2a\u7eb3\u5165\u7814\u7a76\u7684\u836f\u7269\u4e2d\uff0c47<\/span>\u4e2a\u836f\u7269( 75.81%) \u9996\u6b21\u7533\u62a5\u4ee5\u5b64\u513f\u836f\u8fdb\u884c\u4e0a\u62a5; 29<\/span>\u4e2a\u836f\u7269( 46. 77%) \u4ee5\u52a0\u901f\u5ba1\u6279\u5f62\u5f0f\u7533\u62a5; 46 \u4e2a\u836f\u7269<\/span>( 74.19%) \u4ee5\u4f18\u5148\u5ba1\u8bc4\u9014\u5f84\u8fdb\u884c\u7533\u62a5\u3002\u7a81\u7834\u6027\u7597\u6cd5<\/span>\u7684\u5ba1\u8bc4\u9014\u5f84\u4e8e2012 \u5e747 \u6708\u5f00\u59cb\u5b9e\u884c\u3002<\/span><\/p>\n

\u672c\u7814\u7a76\u6d89\u53ca<\/span>\u7684\u836f\u7269\u670930 \u4e2a\uff0c\u5176\u4e2d\u901a\u8fc7\u7a81\u7834\u6027\u7597\u6cd5\u5ba1\u8bc4\u7684\u670917<\/span>\u4e2a( 56.67%) \u30022001 \u5e74\u81f32010 \u5e7412 \u6708\u4efd\u95f4\u7533\u62a5\u7684<\/span>22 \u4e2a\u836f\u7269\u4e2d\uff0c\u67099 \u4e2a\u901a\u8fc7\u5feb\u901f\u901a\u9053\u9014\u5f84\u5ba1\u8bc4\uff3b7\uff3d\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n

\u8ba8\u8bba<\/strong><\/p>\n<\/section>\n<\/section>\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n

1. \u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u53d7\u8bd5\u8005\u9009\u62e9\u7684\u8003\u91cf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u53d7\u8bd5\u8005\u7684\u9009\u62e9\u4ecd\u4ee5\u8fdb\u5c55\u6027\u5b9e\u4f53\u7624\u6216\u8840\u6db2\u80bf\u7624\u60a3\u8005\u4e3a\u4e3b\uff0c\u9009\u62e9\u7279\u5b9a\u9002<\/span>\u5e94\u8bc1\u80bf\u7624\u7c7b\u578b\u7684\u53d7\u8bd5\u8005\u3001\u8fd0\u7528\u751f\u7269\u6807\u5fd7\u7269\u7b5b\u9009\u53d7\u8bd5<\/span>\u8005\u7684\u7814\u7a76\u76f8\u5bf9\u8f83\u5c11\u3002<\/span><\/p>\n

\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u591a\u4f1a\u6d89\u53ca\u5242\u91cf\u9012<\/span>\u589e\u8bd5\u9a8c\u53ca\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u3002\u5728\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u9636<\/span>\u6bb5\uff0c\u9009\u62e9\u8fdb\u5c55\u6027\u5b9e\u4f53\u7624\u4f5c\u4e3a\u7814\u7a76\u4eba\u7fa4; \u5242\u91cf\u62d3\u5c55\u961f\u5217<\/span>\u7814\u7a76\u591a\u4f1a\u7eb3\u5165\u7279\u5b9a\u80bf\u7624\u7c7b\u578b\u6216\u901a\u8fc7\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u7b5b\u9009\u76ee\u6807\u53d7\u8bd5\u8005\u3002<\/span><\/p>\n

\u901a\u8fc7\u8fd9\u6837\u7684\u4e34\u5e8a\u7814\u7a76\u8bbe\u8ba1\uff0c\u53ef\u4ee5<\/span>\u66f4\u65e9\u5bf9\u7814\u7a76\u836f\u7269\u7684\u6709\u6548\u6027\u8fdb\u884c\u8bc4\u4ef7\uff0c\u66f4\u4fbf\u6377\u53ca\u6709\u6548<\/span>\u5730\u786e\u8bc1\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u7684\u4e34\u5e8a\u7ed9\u836f\u5242\u91cf\u3001\u521d\u6b65\u63a2\u7d22<\/span>\u7814\u7a76\u836f\u7269\u5bf9\u76ee\u6807\u53d7\u8bd5\u4eba\u7fa4\u7684\u4e34\u5e8a\u6709\u6548\u6027\u3002<\/span>\u5bf9\u4e8e\u7814\u7a76\u4eba\u7fa4\u9009\u62e9\u7684\u5efa\u8bae: <\/span><\/p>\n

\u2460 \u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u5242<\/span>\u91cf\u9012\u589e\u9636\u6bb5\uff0c\u53d7\u8bd5\u8005\u7684\u9009\u62e9\u4ee5\u5b9e\u4f53\u7624\u6216\u8840\u6db2\u80bf\u7624\u60a3<\/span>\u8005\u4e3a\u4e3b\uff0c\u5e76\u7ed3\u5408\u5242\u91cf\u62d3\u5c55\u8bd5\u9a8c\u7684\u7814\u7a76\u8bbe\u8ba1\u3002<\/span><\/p>\n

\u2461 \u82e5\u540c<\/span>\u7c7b\u836f\u7269\u5df2\u6709\u660e\u786e\u9884\u6d4b\u6027\u7684\u751f\u7269\u6807\u5fd7\u7269\u65f6\uff0c\u5728\u5242\u91cf\u62d3<\/span>\u5c55\u8bd5\u9a8c\u4e2d\u8fd0\u7528\u8be5\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u7b5b\u9009\u53d7\u8bd5\u8005; \u82e5\u540c<\/span>\u7c7b\u836f\u7269\u65e0\u660e\u786e\u9884\u6d4b\u6027\u7684\u751f\u7269\u6807\u5fd7\u7269\u65f6\uff0c\u5728\u5242\u91cf\u9012\u589e<\/span>\u8bd5\u9a8c\u8fc7\u7a0b\u4e2d\u5f00\u5c55\u63a2\u7d22\u7814\u7a76\uff0c\u5728\u5242\u91cf\u62d3\u5c55\u8bd5\u9a8c\u4e2d\u7ee7\u7eed<\/span>\u63a2\u7d22; \u82e5\u53d1\u73b0\u65b0\u7684\u751f\u7269\u6807\u5fd7\u7269\uff0c\u53ef\u4ee5\u8003\u8651\u4e0e\u4e34\u5e8a\u7814\u7a76<\/span>\u540c\u6b65\u5f00\u53d1\u9488\u5bf9\u8be5\u6807\u5fd7\u7269\u7684\u4f34\u968f\u8bca\u65ad\u65b9\u6cd5\u6216\u8bd5\u5242\u3002<\/p>\n

\u2462 \u5728\u5242\u91cf\u62d3\u5c55\u9636\u6bb5\u9009\u62e9\u7eb3\u5165\u7814\u7a76\u53d7\u8bd5\u8005\u7684\u7624\u79cd\u65f6\uff0c\u5efa\u8bae\u7ed3\u5408\u4e34\u5e8a\u7814\u53d1\u7b56\u7565\u3001\u4e34\u5e8a\u5f00\u53d1\u8ba1\u5212\u3001\u76ee\u6807\u4e0a\u5e02\u7684<\/span>\u9002\u5e94\u8bc1\u7684\u5e02\u573a\u60c5\u51b5\u3001\u836f\u653f\u7533\u62a5\u7684\u7b56\u7565\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

2 \u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u8bbe\u8ba1\u7684\u8003\u91cf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u6700\u4e3b\u8981\u7684\u76ee\u6807\u662f\u521d\u6b65\u63a2\u7d22\u7814\u7a76\u836f\u7269\u5728\u4eba\u4f53\u7684\u5b89\u5168\u6027\u4ee5\u53ca\u63a8\u8350\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5242\u91cf\uff0c\u4e3a<\/span>\u8fbe\u5230\u6b64\u76ee\u6807\uff0c\u4e3b\u8981\u9700\u8003\u8651\u7684\u7814\u7a76\u8bbe\u8ba1\u70b9\u4e3a\u5242\u91cf\u9012\u589e<\/span>\u65b9\u6cd5\u7684\u9009\u62e9( \u9996\u5242\u91cf\u548c\u6700\u9ad8\u5242\u91cf\u7684\u9009\u62e9\u3001\u5404\u5242\u91cf\u7ec4<\/span>\u95f4\u9012\u589e\u7684\u5242\u91cf\u3001\u5404\u5242\u91cf\u7ec4\u7684\u4eba\u6570\u3001\u505c\u6b62\u5242\u91cf\u722c\u5761\u53ca\u786e<\/span>\u5b9a\u5242\u91cf\u7684\u65b9\u6cd5) \u3001DLT \u7684\u5b9a\u4e49\u3002<\/span><\/p>\n

\u5728\u6b64\u57fa\u7840\u4e0a\uff0c\u9700\u8003\u8651<\/span>\u662f\u5426\u9700\u8981\u91c7\u7528\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\uff0c\u8fdb\u800c\u8fdb\u4e00\u6b65\u9a8c\u8bc1<\/span>\u901a\u8fc7\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u7ed9\u51fa\u7684\u63a8\u8350\u5242\u91cf\u662f\u5426\u6700\u4e3a\u5408\u9002\uff0c<\/span>\u5e76\u53ef\u8fdb\u4e00\u6b65\u63a2\u7d22\u7814\u7a76\u836f\u7269\u5bf9\u76ee\u6807\u9002\u5e94\u8bc1\u7684\u4e34\u5e8a\u7597<\/span>\u6548\u3002<\/span><\/p>\n

\u540c\u65f6\uff0c\u8bbe\u8ba1\u4e0e\u7814\u7a76\u76ee\u7684\u53ca\u540e\u671f\u4e34\u5e8a\u7814\u53d1\u5f00\u5c55\u76f8<\/span>\u5173\u7684\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u5982\u9884\u6d4b\u7814\u7a76\u836f\u7269\u7597\u6548\u7684\u751f\u7269\u6807\u5fd7<\/span>\u7269\u7684\u63a2\u7a76\u53ca\u5176\u68c0\u6d4b\u8bd5\u5242\u3001\u65b9\u6cd5\u7684\u7814\u7a76\u3002<\/span><\/p>\n

2.1 \u5242\u91cf\u9012\u589e\u65b9\u6cd5\u9009\u62e9\u7684\u8003\u91cf<\/strong><\/p>\n

\u4ece\u672c\u7814\u7a76\u5206\u6790\u7684\u6570\u636e\u53ef\u4ee5\u770b\u51fa\uff0c\u5bf9\u4e8e\u5242\u91cf\u9012\u589e\u65b9\u6cd5\u7684\u9009\u62e9\uff0c\u4ecd\u4ee5\u4f20\u7edf<\/span>3 + 3 \u8bbe\u8ba1\u4e3a\u4e3b\uff0c\u5bf9\u4e8e\u6539\u826f\u7684\u65b9\u6cd5\uff0c\u5982\u5feb\u901f\u6ef4\u5b9a\u6cd5\u3001\u57fa<\/span>\u4e8e\u6a21\u578b\u8bbe\u8ba1\u8fd0\u7528\u5f97\u8fd8\u4e0d\u662f\u5f88\u591a\u3002<\/span><\/p>\n

\u76f8\u5bf9\u4e8e\u4f20\u7edf\u76843 +<\/span>3 \u5242\u91cf\u9012\u589e\u65b9\u6cd5\uff0c\u6539\u826f\u7684\u65b9\u6cd5\u5728\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u5242<\/span>\u91cf\u9009\u62e9\u4e0a\u6709\u4e00\u5b9a\u7684\u4f18\u52bf\uff3b8\uff3d\u3002<\/span><\/p>\n

\u4f46\u4ece\u672c\u7814\u7a76\u7eb3\u5165\u7684\u836f<\/span>\u7269\u6765\u770b\uff0c\u6539\u826f\u578b\u7684\u5242\u91cf\u9012\u589e\u65b9\u6cd5\u5728\u65e9\u671f\u7814\u7a76\u4e2d\u8fd0\u7528<\/span>\u5e76\u4e0d\u591a\uff0c\u539f\u56e0\u53ca\u6311\u6218\u53ef\u80fd\u4e3a\uff3b9\uff3d:<\/span><\/p>\n

 \u2460 \u9700\u8981\u7814\u7a76\u8005\u53ca\u751f<\/span>\u7269\u7edf\u8ba1\u5e08\u5728\u5242\u91cf\u9012\u589e\u9636\u6bb5\u7d27\u5bc6\u7684\u5408\u4f5c\uff0c\u6267\u884c\u8fc7\u7a0b\u4e2d<\/span>\u53ef\u80fd\u4f1a\u9762\u4e34\u7f3a\u4e4f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u7814\u7a76\u8005\u548c\u4e13\u4e1a\u7684\u751f\u7269\u7edf<\/span>\u8ba1\u4eba\u624d\u3002<\/span><\/p>\n

\u2461 \u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u9700\u8981\u7eb3\u5165\u7814\u7a76\u7684\u53d7\u8bd5\u8005<\/span>\u4f8b\u6570\u589e\u591a\uff0c\u5355\u4e00\u7814\u7a76\u4e2d\u5fc3\u4e0d\u80fd\u6ee1\u8db3\u8bd5\u9a8c\u5165\u7ec4\u91cf\u7684\u9700<\/span>\u6c42\uff0c\u8fdb\u800c\u9700\u8981\u540c\u65f6\u5728\u591a\u4e2a\u4e2d\u5fc3\u5f00\u5c55\u65e9\u671f\u7814\u7a76\uff0c\u6253\u7834\u4e86<\/span>\u5355\u4e2d\u5fc3\u5f00\u5c55\u2160\u671f\u7814\u7a76\u7684\u6a21\u5f0f\u3002<\/span><\/p>\n

\u2462 \u4f4e\u5242\u91cf\u6c34\u5e73\u53d7\u8bd5<\/span>\u8005\u7684\u51cf\u5c11\uff0c\u5bf9\u836f\u52a8\u5b66\u4e0e\u836f\u6548\u5b66\u6570\u636e\u7684\u6536\u96c6\u548c\u5206\u6790\u76f8<\/span>\u5bf9\u4e0d\u8db3\u3002<\/span><\/p>\n

\u2463 \u7814\u7a76\u8005\u3001\u4f26\u7406\u59d4\u5458\u4f1a\u5bf9\u65b0\u65b9\u6cd5\u7684\u4e86\u89e3\u4e0d<\/span>\u8db3\uff0c\u7f3a\u4e4f\u6539\u826f\u5242\u91cf\u9012\u589e\u65b9\u6cd5\u8fd0\u7528\u7684\u7ecf\u9a8c\u3002<\/span><\/p>\n

\u5bf9\u4e8e\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u5242\u91cf\u9012\u589e\u65b9\u6cd5\uff0c\u5efa\u8bae\u9009\u62e9<\/span>3 + 3 \u53ca\u6539\u826f\u578b\u5242\u91cf\u9012\u589e\u65b9\u6cd5\uff0c\u542c\u53d6\u7ecf\u9a8c\u4e30\u5bcc\u7684\u7814\u7a76<\/span>\u8005\u548c\u4e13\u4e1a\u7684\u751f\u7269\u7edf\u8ba1\u5e08\u7684\u5efa\u8bae; \u6839\u636e\u7814\u7a76\u75c5\u4f8b\u6570\u3001\u5242<\/span>\u91cf\u6c34\u5e73\u3001PK\/PD \u6570\u636e\u6536\u96c6\u591a\u65b9\u9762\u54a8\u8be2\u8fdb\u884c\u9009\u62e9\u3002<\/span><\/p>\n

\u5728<\/span>\u8bc4\u4f30\u7814\u7a76\u836f\u7269\u7279\u70b9\u3001\u7814\u7a76\u4eba\u5458\u53ca\u7ecf\u9a8c\u4e30\u5bcc\u7684\u751f\u7269\u7edf<\/span>\u8ba1\u5e08\u4eba\u5458\u914d\u7f6e\u3001\u7814\u7a76\u4e0e\u5408\u4f5c\u8ba1\u5212\u5145\u5206\u7684\u524d\u63d0\u4e0b\uff0c\u91c7\u7528<\/span>\u6539\u826f\u578b\u5242\u91cf\u9012\u589e\u65b9\u6cd5\u3002\u82e5\u4e0d\u5177\u5907\u6b64\u6761\u4ef6\uff0c\u5efa\u8bae\u4ecd\u4ee5<\/span>\u4f20\u7edf3 + 3 \u5242\u91cf\u9012\u589e\u65b9\u6cd5\u5e76\u5728\u5355\u4e2d\u5fc3\u5f00\u5c55\u3002<\/span><\/p>\n

2.2 \u65e9\u671f\u8bd5\u9a8c\u4e2dDLT \u5b9a\u4e49\u7684\u8003\u91cf<\/strong><\/p>\n

\u4ece\u672c\u7814\u7a76\u5206\u6790\u7684\u6570\u636e\u53ef\u4ee5\u770b\u51fa\uff0c\u7f8e\u56fdFDA \u6279\u51c6\u4e0a\u5e02\u7684\u6297\u80bf\u7624\u9776\u5411<\/span>\u836f\u7269\u5728\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5bf9DLT \u7684\u5b9a\u4e49\u591a\u4e3a\u4e0e\u7814\u7a76\u836f\u7269\u76f8\u5173\u76843 \u7ea7\u4ee5\u4e0a\u7684\u975e\u8840\u6db2\u5b66\u6bd2\u6027\u53ca\u22654 \u7ea7\u7684\u8840<\/span>\u6db2\u6027\u6bd2\u6027\uff0c\u591a\u4f1a\u5bf9\u4e2d\u6027\u7c92\u7ec6\u80de\u5f15\u8d77\u7684\u53d1\u70ed\u8fdb\u884c\u5b9a\u4e49\uff0c<\/span>\u540c\u65f6\u6839\u636e\u7814\u7a76\u836f\u7269\u7684\u6bd2\u6027\u7279\u70b9\uff0c\u5bf9\u80c3\u80a0\u9053\u53cd\u5e94\u3001\u809d\u80be<\/span>\u529f\u80fd\u635f\u4f24\u3001\u7528\u836f\u540e\u53ef\u80fd\u4ea7\u751f\u5f02\u5e38\u751f\u7406\u73b0\u8c61\u3001\u56e0\u5b89\u5168\u6027<\/span>\u95ee\u9898\u800c\u5242\u91cf\u8c03\u6574\u6216\u505c\u836f\u7684\u65f6\u95f4\u8fdb\u884c\u5b9a\u4e49; \u5e76\u5bf9DLT<\/span>\u76f8\u5173\u7684\u5b89\u5168\u6027\u4e8b\u4ef6\u89c2\u5bdf\u65f6\u95f4\u5b9a\u4e49\u4e3a\u7b2c\u4e00\u4e2a\u7ed9\u836f\u5468\u671f\u3002<\/span><\/p>\n

\u4f46\u662f\uff0c\u76f8\u6bd4\u7ec6\u80de\u6bd2\u6027\u836f\u7269\u5bfc\u81f4\u7684DLT \u53d1\u751f\u65f6\u95f4\u901a\u5e38\u4f1a\u5728\u7528\u836f\u540e\u4e0d\u4e45\uff0c\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u5b58\u5728\u8fdf\u53d1\u6216<\/span>\u8f7b\u5ea6\u84c4\u79ef\u7684\u6bd2\u6027\u4e14\u4e0d\u5728DLT \u8bc4\u4f30\u7a97\u53e3\u5185\uff0c\u5bfc\u81f4\u4f20\u7edf<\/span>\u7684DLT \u7684\u5b9a\u4e49\u4e0d\u80fd\u9002\u7528\u4e8e\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u3002<\/span><\/p>\n

\u4e0d\u826f<\/span>\u4e8b\u4ef6\u7684\u8bc4\u4f30\u65f6\u95f4\u3001\u4e25\u91cd\u7ea7\u522b\u3001\u53ef\u9006\u7684\u6216\u6301\u7eed\u7684\u6bd2\u6027\u5747<\/span>\u9700\u88ab\u8003\u8651\u5728DLT \u7684\u5b9a\u4e49\u4e2d\uff0c\u5e76\u6d89\u53ca\u7b2c1 \u4e2a\u6cbb\u7597\u5468\u671f<\/span>\u65f6\u95f4\u5916\u53d1\u751f\u7684\u6709\u610f\u4e49\u7684\u76f8\u5173\u6bd2\u6027\u3002<\/span><\/p>\n

\u4e00\u9879\u5bf936 \u4e2a\u5206<\/span>\u5b50\u9776\u5411\u836f\u7269\u7684\u7814\u7a76\u663e\u793a\uff0c\u8d85\u8fc7\u4e00\u534a\u7684\u53d7\u8bd5\u8005\u7684\u6bd2\u526f<\/span>\u53cd\u5e94\u53d1\u751f\u5728\u7b2c1 \u4e2a\u7ed9\u836f\u5468\u671f\u540e\uff0c\u8d85\u8fc7\u4e00\u534a\u76843 \u62164\u7ea7\u6bd2\u6027\u53d1\u751f\u5728\u7b2c1 \u4e2a\u7ed9\u836f\u5468\u671f\u4ee5\u540e\u3002<\/span><\/p>\n

\u9664\u4e86\u4e25\u91cd\u76843<\/span>\u7ea7\u4ee5\u4e0a\u4e0d\u826f\u4e8b\u4ef6\uff0c\u9776\u5411\u836f\u7269\u4f1a\u5f15\u8d77\u91cd\u590d\u7684\u6162\u6027\u4f4e\u7ea7<\/span>\u522b\u7684\u4e0d\u826f\u4e8b\u4ef6\uff0c\u5f71\u54cd\u53d7\u8bd5\u8005\u7684\u751f\u6d3b\u8d28\u91cf\uff3b10\uff3d\u3002\u56e0\u6b64\uff0c<\/span>\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u65e9\u671fDLT \u7684\u5b9a\u4e49\u53ef\u80fd\u9700\u8981\u91c7\u7528\u65b0<\/span>\u7684\u5b9a\u4e49\u4e0e\u8bc4\u4f30\u65b9\u6cd5\u3002<\/span><\/p>\n

2.3 \u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u7684\u8fd0\u7528\u8003\u91cf<\/strong><\/p>\n

\u4ece\u672c\u7814\u7a76\u7684\u6570\u636e\u53ef\u4ee5\u770b\u51fa\uff0c\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u5728\u7f8e\u56fdFDA \u6279\u51c6<\/span>\u4e0a\u5e02\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u7684\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8fd0\u7528\u5448\u589e\u957f<\/span>\u8d8b\u52bf\uff0c\u5728\u6574\u4e2a\u4e34\u5e8a\u7814\u53d1\u4e2d\u7684\u4f5c\u7528\u4e5f\u6108\u52a0\u91cd\u8981\u3002<\/span><\/p>\n

\u4e00\u9879<\/span>\u7814\u7a76\u6536\u96c6\u4e862006\u20142011 \u5e74\u516c\u5f00\u53d1\u8868\u7684\u6297\u80bf\u7624\u836f\u7269<\/span>\u7684\u2160\u671f\u3001\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u63a2\u7d22\u4e86\u2160\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6d89\u53ca\u5242<\/span>\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u4e0e\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u7f8e\u56fdFDA \u6279\u51c6<\/span>\u4e0a\u5e02\u65f6\u95f4\u7684\u5173\u7cfb\u3002<\/span><\/p>\n

\u7814\u7a76\u8868\u660e\uff0c\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u6d89<\/span>\u53ca\u7684\u4eba\u6570\u57282 \u4eba\u4ee5\u4e0a\u7684\u76f8\u5bf9\u4e8e\u6ca1\u6709\u5f00\u5c55\u5242\u91cf\u62d3\u5c55\u961f<\/span>\u5217\u7814\u7a76\u7684\u836f\u7269\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u6210\u529f\u7387\u9ad8\u3002\u540c\u65f6\uff0c\u8fd0<\/span>\u7528\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u7684\u836f\u7269\u53ef\u4ee5\u63d0\u9ad8\u7814\u7a76\u836f\u7269\u5728\u7f8e<\/span>\u56fdFDA \u76845 \u5e74\u6279\u51c6\u7387\uff0c\u51f8\u663e\u51fa\u5242\u91cf\u62d3\u5c55\u7814\u7a76\u5728\u6297\u80bf<\/span>\u7624\u836f\u7269\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u8fd0\u7528\u7684\u91cd\u8981\u6027\uff3b11\uff3d\u3002<\/span><\/p>\n

\u56e0\u6b64\uff0c\u5efa\u8bae\u5728\u5f00\u5c55\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u7684\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u65f6\uff0c\u5c06\u5242\u91cf\u62d3\u5c55\u961f\u5217\u7814\u7a76\u7eb3\u5165\u65e9\u671f\u7814\u7a76\u8bbe\u8ba1\u4e2d\uff0c<\/span>\u4ece\u800c\u63d0\u9ad8\u7814\u7a76\u836f\u7269\u7684\u7814\u53d1\u6210\u529f\u7387\u3002<\/span><\/p>\n

\u5242\u91cf\u62d3\u5c55\u7814\u7a76\u7684<\/span>\u8fd0\u7528\u4f1a\u589e\u52a0\u7eb3\u5165\u7814\u7a76\u53d7\u8bd5\u8005\u7684\u6570\u91cf\uff0c\u4e3a\u4e86\u4fdd\u969c\u7814\u7a76<\/span>\u8fdb\u5ea6\u548c\u51cf\u5c11\u7814\u7a76\u504f\u501a\uff0c\u5efa\u8bae\u5728\u591a\u4e2a\u4e2d\u5fc3\u540c\u65f6\u5f00\u5c55\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

3 \u4e34\u5e8a\u7814\u53d1\u7b56\u7565\u53ca\u836f\u653f\u7533\u62a5\u7b56\u7565\u89d2\u5ea6\u8003\u91cf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u5728\u5b8c\u6210\u65b0\u836f\u7684\u4e34\u5e8a\u524d\u5404\u9879\u7814\u7a76\u7684\u524d\u63d0\u4e0b\uff0c\u836f\u7269\u7814\u53d1\u4eba\u5458\u53ca\u6295\u8d44\u65b9\uff0c\u9700\u8981\u5236\u5b9a\u5b8c\u5584\u7684\u4e34\u5e8a\u7814\u53d1\u7b56\u7565\uff0c<\/span>\u4e3b\u8981\u4ece\u533b\u5b66\u7b56\u7565\u3001\u836f\u653f\u7533\u62a5\u7b56\u7565\u3001\u5e02\u573a\u7b56\u75653 \u4e2a\u65b9\u9762<\/span>\u8fdb\u884c\u8003\u91cf\u3002<\/span><\/p>\n

\u4ece\u672c\u7814\u7a76\u5206\u6790\u7684\u6570\u636e\u53ef\u4ee5\u770b\u51fa\uff0c\u7eb3\u5165\u7814<\/span>\u7a76\u7684\u6297\u80bf\u7624\u9776\u5411\u836f\u7269\u5747\u91c7\u7528\u4e86\u4f18\u60e0\u7684\u5ba1\u6279\u653f\u7b56\uff0c\u9ad8<\/span>\u8fbe70%\u7684\u836f\u7269\u91c7\u7528\u4e86\u5b64\u513f\u836f\u53ca\u4f18\u5148\u5ba1\u8bc4\u653f\u7b56\uff0c\u534a\u6570<\/span>\u5de6\u53f3\u7684\u836f\u7269\u91c7\u7528\u4e86\u7a81\u7834\u6027\u7597\u6cd5\u3001\u52a0\u901f\u5ba1\u6279\u3001\u5feb\u901f\u901a\u9053<\/span>\u7684\u5ba1\u8bc4\u65b9\u5f0f\u3002<\/span><\/p>\n

\u6240\u4ee5\u5728\u836f\u7269\u7814\u53d1\u65e9\u671f\u5236\u5b9a\u836f\u653f\u7533\u62a5\u7b56<\/span>\u7565\u53ef\u4ee5\u7f29\u77ed\u836f\u7269\u6279\u51c6\u4e0a\u5e02\u7684\u65f6\u95f4\u3002<\/span><\/p>\n

3.1 \u591a\u5b66\u79d1\u5408\u4f5c\uff0c\u5236\u5b9a\u4e34\u5e8a\u7814\u53d1\u8ba1\u5212\u4e66<\/strong><\/p>\n

\u7531\u4e8e\u836f\u7269\u5f00\u53d1\u9636\u6bb5\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u4e0e\u4e34\u5e8a\u7814\u7a76\u6d89\u53ca\u591a\u4e2a\u4e0d\u540c\u7684<\/span>\u4e13\u4e1a\u9886\u57df\uff0c\u56e0\u6b64\u5728\u836f\u7269\u7814\u53d1\u8fc7\u7a0b\u4e2d\u6709\u673a\u5730\u7edf\u7b79\u548c\u6574<\/span>\u5408\u5404\u4e13\u4e1a\u9886\u57df\u7684\u4fe1\u606f\u5bf9\u7814\u53d1\u7ba1\u7406\u5c24\u4e3a\u91cd\u8981\u3002<\/span><\/p>\n

\u5efa\u8bae\u4e34<\/span>\u5e8a\u524d\u7814\u7a76\u4eba\u5458\u4e0e\u4e34\u5e8a\u7814\u7a76\u4eba\u5458\u5efa\u7acb\u5408\u4f5c\u56e2\u961f\u53ca\u6c9f\u901a<\/span>\u673a\u5236\uff0c\u56e2\u961f\u4eba\u5458\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u836f\u5b66\u4e13\u5bb6\u3001\u836f\u7406\u6bd2\u7406\u4e13<\/span>\u5bb6\u3001\u4e34\u5e8a\u4e13\u5bb6\u3001\u836f\u653f\u4e13\u5bb6\u3001\u7edf\u8ba1\u4e13\u5bb6\u3001\u5e02\u573a\u8425\u9500\u4e13\u5bb6\u3001<\/span>\u76ee\u6807\u4e0a\u5e02\u9002\u5e94\u8bc1\u60a3\u8005\u7fa4\u4f53\u7b49\uff0c\u591a\u89d2\u8272\u5730\u53c2\u4e0e\u5c06\u5bf9\u6574<\/span>\u4e2a\u836f\u7269\u7814\u53d1\u751f\u547d\u5468\u671f\u7684\u8ba1\u5212\u5236\u5b9a\u548c\u8fdb\u7a0b\u7ba1\u7406\u5177\u6709\u91cd<\/span>\u8981\u7684\u4f5c\u7528\u3002<\/span><\/p>\n

3.2 \u4ea7\u54c1\u7279\u6027\u5206\u6790<\/strong><\/p>\n

\u5145\u5206\u5206\u6790\u7814\u7a76\u836f\u7269\u7684\u7279\u70b9\u548c\u4f18\u52bf; \u5173\u6ce8\u540c\u7c7b\u4ea7\u54c1\u6216\u5176\u4ed6\u7ade\u4e89\u4ea7\u54c1\u5728\u76ee\u524d\u53ca\u672a\u6765<\/span>\u4e34\u5e8a\u5e02\u573a\u7684\u524d\u666f; \u5206\u6790\u7814\u7a76\u836f\u7269\u9884\u671f\u4e0a\u5e02\u7684\u9002\u5e94\u8bc1\u3001<\/span>\u4e34\u5e8a\u8bca\u7597\u6807\u51c6\u3001\u5e38\u7528\u6cbb\u7597\u65b9\u6cd5\u3001\u76ee\u524d\u6cbb\u7597\u836f\u7269\u7684\u4f7f\u7528\u60c5\u51b5\uff0c\u8fdb\u4e00\u6b65\u5206\u6790\u672c\u7814\u7a76\u836f\u7269\u7684\u4f18\u52bf; \u4ece\u591a\u4e2a\u76ee\u6807\u9002<\/span>\u5e94\u8bc1\u89d2\u5ea6\u8fdb\u884c\u5206\u6790\uff0c\u5bf9\u7814\u7a76\u836f\u7269\u6210\u529f\u4e0a\u5e02\u7684\u53ef\u80fd\u6027<\/span>\u53ca\u65f6\u95f4\u8fdb\u884c\u8bc4\u4f30\uff0c\u53ca\u65e9\u660e\u786e\u7533\u8bf7\u4eba\u5bf9\u7814\u7a76\u836f\u7269\u7684\u4e34<\/span>\u5e8a\u5b9a\u4f4d\u3002<\/span><\/p>\n

3.3 \u836f\u653f\u7533\u62a5\u8003\u8651<\/strong><\/p>\n

\u5728\u7814\u53d1\u8fdb\u5165\u5173\u952e\u9636\u6bb5\u65f6\u5e94\u53ca\u65f6\u4e0e\u836f\u653f\u5f53\u5c40\u6c9f\u901a\u7814\u53d1\u601d\u8def\u3001\u9636\u6bb5\u6027\u7814\u7a76\u7ed3\u679c\u53ca\u540e<\/span>\u7eed\u5f00\u53d1\u8ba1\u5212\u3002<\/span><\/p>\n

\u6df1\u5165\u4e86\u89e3\u836f\u653f\u6cd5\u89c4\uff0c\u529b\u4e89\u8fd0\u7528\u65b0\u836f\u7684<\/span>\u5404\u79cd\u4f18\u5148\u5ba1\u8bc4\u653f\u7b56\uff0c\u5e76\u5728\u5236\u5b9a\u65e9\u671f\u836f\u7269\u7814\u53d1\u7b56\u7565\u65f6<\/span>\u7ed9\u4e88\u5145\u5206\u8003\u8651\u3002\u56fd\u5185\u7814\u53d1\u65b0\u836f\u65f6\uff0c\u82e5\u8ba1\u5212\u5728\u591a\u4e2a\u56fd<\/span>\u5bb6\u4e0a\u5e02\uff0c\u9700\u5145\u5206\u4e86\u89e3\u62df\u7533\u62a5\u5404\u56fd\u7684\u836f\u54c1\u6cd5\u89c4\u653f\u7b56\uff0c\u5e76<\/span>\u8003\u8651\u4f18\u5148\u5f00\u5c55\u7684\u56fd\u5bb6\u3002<\/span><\/p>\n

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<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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