{"id":99161,"date":"2019-04-26T00:00:50","date_gmt":"2019-05-17T08:19:41","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/99161\/"},"modified":"2019-05-17T16:19:42","modified_gmt":"2019-05-17T08:19:42","slug":"8c9260d247","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/99161\/","title":{"rendered":"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"xmteditor\" style=\"display:none;\"  ><\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;font-size: 15px;line-height: 1.8;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"margin-bottom: -12px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: bottom;width: 6px;box-sizing: border-box;\">\n<section style=\"width: 2px;margin: auto;height: 16px;background-color: rgb(17, 19, 22);box-sizing: border-box;\"><\/section>\n<section style=\"width: 6px;height: 6px;border-radius: 50%;background-color: rgb(17, 19, 22);box-sizing: border-box;\"><\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: 60%;height: 1px;box-sizing: border-box;\"><\/section>\n<section style=\"display: inline-block;vertical-align: bottom;width: 6px;box-sizing: border-box;\">\n<section style=\"width: 2px;margin: auto;height: 16px;background-color: rgb(17, 19, 22);box-sizing: border-box;\"><\/section>\n<section style=\"width: 6px;height: 6px;border-radius: 50%;background-color: rgb(17, 19, 22);box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section style=\"margin-left: auto;transform: rotate(0deg);-webkit-transform: rotate(0deg);-moz-transform: rotate(0deg);-o-transform: rotate(0deg);margin-bottom: -5px;width: 5px;height: 5px;background-color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<section style=\"border-right: 5px solid rgb(28, 161, 255);border-bottom: 5px solid rgb(28, 161, 255);border-top-color: rgb(28, 161, 255);border-left-color: rgb(28, 161, 255);box-sizing: border-box;\">\n<section style=\"padding: 10px;border-color: rgb(28, 161, 255);border-width: 1px;border-radius: 0px;border-style: dashed;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"line-height: 1.75;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u8fd1\u4e24\u5e74\uff0c\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u5174\u8d77\u5e76\u8fc5\u901f\u6210\u4e3a\u5404\u5927\u56fd\u9645\u4f1a\u8bae\u7684\u70ed\u70b9\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u76ee\u524d\uff0c\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u7b49\u6297 PD-1 \u6297\u4f53\u5728\u80c3\u764c\u540e\u7ebf\u6cbb\u7597\u5df2\u7ecf\u4e2d\u53d6\u5f97\u4e86\u786e\u5207\u7684\u7ed3\u679c\u3002\u7814\u7a76\u867d\u521d\u89c1\u6210\u6548\uff0c\u4f46\u4ecd\u65e7\u4efb\u91cd\u9053\u8fdc\uff0c\u672a\u6765\u514d\u75ab\u6cbb\u7597\u7684\u6f5c\u5728\u83b7\u76ca\u4eba\u7fa4\u6709\u54ea\u4e9b\u3001\u53c8\u5c06\u9762\u4e34\u54ea\u4e9b\u6311\u6218\uff1f<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5173\u4e8e\u8fd9\u4e9b\u95ee\u9898\uff0c\u5728\u672c\u671f\u4e13\u8bbf\u4e2d\uff0c<strong style=\"box-sizing: border-box;\">\u4e2d\u5c71\u5927\u5b66\u9644\u5c5e\u7b2c\u516d\u533b\u9662 \u9093\u8273\u7ea2\u6559\u6388<\/strong> 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\/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"width: 8px;height: 8px;border-radius: 50%;margin: auto;background-color: rgb(0, 0, 0);box-sizing: border-box;\"><\/section>\n<section style=\"width: 22px;margin-top: -5px;margin-right: auto;margin-left: auto;box-sizing: border-box;\">\n<section style=\"height: 20px;transform: rotate(45deg);-webkit-transform: rotate(45deg);-moz-transform: rotate(45deg);-o-transform: rotate(45deg);transform-origin: left center;-webkit-transform-origin: left center;-moz-transform-origin: left center;-o-transform-origin: left center;float: left;border-left: 1px solid rgb(28, 161, 255);border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"height: 20px;border-left: 1px solid rgb(28, 161, 255);transform: rotate(-45deg);-webkit-transform: rotate(-45deg);-moz-transform: rotate(-45deg);-o-transform: rotate(-45deg);transform-origin: right center;-webkit-transform-origin: right center;-moz-transform-origin: right center;-o-transform-origin: right center;float: right;border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"clear: both;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;margin-top: -3px;border-radius: 5px;color: rgb(255, 255, 255);background-color: rgb(28, 161, 255);padding: 2px 8px;font-size: 17px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u76ee\u524d\u6bd4\u8f83\u786e\u5207\u7684\u6cbb\u7597\u4eba\u7fa4<\/strong><\/p>\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u662f\u63a5\u53d7\u4e09\u7ebf\u6cbb\u7597\u7684\u60a3\u8005<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"line-height: 1.75;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u4ece\u9ed1\u8272\u7d20\u7624\u5230\u80ba\u764c\uff0c\u514d\u75ab\u6cbb\u7597\u7684\u70ed\u5ea6\u5df2\u7ecf\u6301\u7eed\u4e86\u591a\u5e74\uff0c\u8fd1\u4e24\u5e74\uff0c\u514d\u75ab\u6cbb\u7597\u4e5f\u5f00\u59cb\u6210\u4e3a\u80c3\u80a0\u9053\u80bf\u7624\u7684\u7814\u7a76\u70ed\u70b9\u3002<span style=\"letter-spacing: 0px;box-sizing: border-box;\">\u5927\u5bb6\u5173\u6ce8\u8f83\u591a\u7684\u56fd\u9645\u4f1a\u8bae\uff0c\u6bd4\u5982 ASCO\uff08\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5e74\u4f1a\uff09\uff0c\u4ee5\u53ca\u521a\u521a\u7ed3\u675f\u7684 ASCO-GI\uff08ASCO\u80c3\u80a0\u80bf\u7624\u7814\u8ba8\u4f1a\uff09\uff0c\u6700\u8fd1\u7684\u7814\u7a76\u8fdb\u5c55\u57fa\u672c\u4e0a\u90fd\u4e0e\u514d\u75ab\u6cbb\u7597\u76f8\u5173\uff0c\u6240\u4ee5\u8bf4\uff0c\u514d\u75ab\u6cbb\u7597\u4e3a\u80c3\u80a0\u80bf\u7624\u7684\u6cbb\u7597\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\u3002<\/span><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"box-sizing: border-box;color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u5728\u80c3\u764c\u9886\u57df\uff0c\u514d\u75ab\u6cbb\u7597\u76ee\u524d\u6bd4\u8f83\u786e\u5b9a\u7684\u3001\u6709\u7528\u7684\u4eba\u7fa4\u662f\u63a5\u53d7\u4e09\u7ebf\u6cbb\u7597\u7684\u60a3\u8005<\/strong>\u3002<\/span><span style=\"color: rgba(62, 62, 62, 0.86);box-sizing: border-box;\"><\/span><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u7814\u7a76\u5206\u522b\u6709 Nivolumab \u5355\u6297\uff08\u7eb3\u6b66\u5229\u5c24\u5355\u6297\uff09\u7684 ATTRACTION-02 \u7814\u7a76\u548c Pembrolizumab\uff08\u5e15\u535a\u5229\u73e0\u5355\u6297\uff09\u7684 KEYNOTE-059 \u7814\u7a76\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">ATTRACTION-02 \u7814\u7a76\u5e94\u8be5\u8bf4\u662f\u4e00\u4e2a\u9a8c\u8bc1\u5b9e\u9a8c\uff0c\u662f\u4e00\u4e2a\u975e\u5e38\u5b8c\u7f8e\u7684\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u7814\u7a76\u3002\u7eb3\u5165\u7684\u4eba\u7fa4\u53ea\u6709\u4e9a\u6d32\u4eba\uff0c\u5c3d\u7ba1\u4e2d\u56fd\u5927\u9646\u60a3\u8005\u6ca1\u6709\u53c2\u52a0\uff0c\u4f46\u7814\u7a76\u5165\u7ec4\u4e86\u4e00\u90e8\u5206\u53f0\u6e7e\u60a3\u8005\uff0c\u6240\u4ee5\u8fd9\u4e2a\u7814\u7a76\u5bf9\u4e8e\u4e9a\u6d32\u60a3\u8005\u6216\u8005\u9ec4\u79cd\u4eba\u7684\u6cbb\u7597\u662f\u6709\u5f88\u660e\u786e\u7684\u6307\u5bfc\u610f\u4e49\u7684\u3002\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cNivolumab \u6cbb\u7597\u7ec4\u7684 PFS\uff08\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff09\uff0cOS\uff08\u603b\u751f\u5b58\u671f\uff09\uff0c\u8fd8\u6709 ORR\uff08\u5ba2\u89c2\u7f13\u89e3\u7387\uff09\u90fd\u6709\u660e\u663e\u7684\u63d0\u9ad8\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u6240<span style=\"box-sizing: border-box;\">\u4ee5<span style=\"background-color: rgba(1, 0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u9093\u6559\u6388\u8ba4\u4e3a\uff0c\u80c3\u764c\u7684\u4e09\u7ebf\u6cbb\u7597\uff0c\u6297 PD-1 \u6297\u4f53 Nivolumab \u5e94\u8be5\u4f5c\u4e3a\u6807\u51c6\u6cbb\u7597\u4e4b\u4e00<\/strong><\/span><\/span>\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u5173\u4e8e Pembrolizumab\uff0c\u4e5f\u6709\u4e00\u4e9b\u80c3\u764c\u4e09\u7ebf\u6cbb\u7597\u9886\u57df\u7684\u7814\u7a76\u5de5\u4f5c\uff0c\u4f46\u76ee\u524d\u6ca1\u6709\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u7814\u7a76\u3002KEYNOTE-059 \u6709\u4e00\u4e2a\u5355\u81c2\uff0c\u63a2\u8ba8 PD-1 \u6297\u4f53 Pembrolizumab \u5355\u836f\u4e09\u7ebf\u6cbb\u7597\u665a\u671f\u80c3\u764c\u7684\u7597\u6548\uff0c\u4ece\u6570\u636e\u4e0a\u6765\u770b\uff0c\u5b83\u8ddf ATTRACTION-02 \u7684\u7814\u7a76\u6570\u636e\u662f\u6bd4\u8f83\u63a5\u8fd1\u7684\u3002\u53e6\u5916\uff0c\u8be5\u7814\u7a76\u8fd8\u9488\u5bf9 PD-L1 \u8868\u8fbe\u8fdb\u884c\u4e86\u4e9a\u7ec4\u5206\u6790\uff0cPD-L1 \u9633\u6027\u60a3\u8005\u7684\u6709\u6548\u7387\u4f1a\u66f4\u9ad8\u4e00\u4e9b\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"width: 8px;height: 8px;border-radius: 50%;margin: auto;background-color: rgb(0, 0, 0);box-sizing: border-box;\"><\/section>\n<section style=\"width: 22px;margin-top: -5px;margin-right: auto;margin-left: auto;box-sizing: border-box;\">\n<section style=\"height: 20px;transform: rotate(45deg);-webkit-transform: rotate(45deg);-moz-transform: rotate(45deg);-o-transform: rotate(45deg);transform-origin: left center;-webkit-transform-origin: left center;-moz-transform-origin: left center;-o-transform-origin: left center;float: left;border-left: 1px solid rgb(28, 161, 255);border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"height: 20px;border-left: 1px solid rgb(28, 161, 255);transform: rotate(-45deg);-webkit-transform: rotate(-45deg);-moz-transform: rotate(-45deg);-o-transform: rotate(-45deg);transform-origin: right center;-webkit-transform-origin: right center;-moz-transform-origin: right center;-o-transform-origin: right center;float: right;border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"clear: both;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;margin-top: -3px;border-radius: 5px;color: rgb(255, 255, 255);background-color: rgb(28, 161, 255);padding: 2px 8px;font-size: 17px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u514d\u75ab\u8054\u5408\u6cbb\u7597\u662f\u76ee\u524d\u4e3b\u6d41\u7684\u63a2\u7d22\u65b9\u5411\uff0c\u800c\u6709\u53ef\u80fd\u53d6\u5f97\u7a81\u7834\u6027\u8fdb\u5c55\u7684\u9886\u57df\u4e4b\u4e00\u662fEB\u75c5\u6bd2\u6216HP\u611f\u67d3\u76f8\u5173\u6027\u80c3\u764c<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"line-height: 1.75;box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u76ee\u524d\u5173\u4e8e\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u7684\u7814\u7a76\u6709\u5f88\u591a\uff0c\u4e3b\u8981\u662f PD-1\/PD-L1 \u6297\u4f53\u4e0e\u6807\u51c6\u5316\u7597\u8054\u5408\u7684\u7814\u7a76\uff0c\u5e94\u8be5\u8bf4\u8fd9\u662f\u56fd\u5185\u73b0\u5728\u6bd4\u8f83\u4e3b\u6d41\u7684\u63a2\u7d22\u65b9\u5411\u3002<\/strong><\/span><strong style=\"box-sizing: border-box;\"><\/strong>\u300c\u5305\u62ec\u6211\u4eec\u81ea\u5df1\u4e2d\u5fc3\u4e5f\u53c2\u52a0\u4e86\u4e09\u9879\u4ee5\u4e0a PD-1 \u5355\u6297\u80c3\u764c\u4e00\u7ebf\u6cbb\u7597\u7684\u4e34\u5e8a\u7814\u7a76\u300d\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u80c3\u764c\u662f\u5404\u4e2a\u56fd\u5bb6\u90fd\u975e\u5e38\u91cd\u89c6\u7684\u7624\u79cd\uff0c\u4f46\u5728\u514d\u75ab\u6cbb\u7597\u65b9\u9762\uff0c\u80c3\u764c\u76ee\u524d\u8fd8\u8ddf\u5728\u5176\u4ed6\u7624\u79cd\u4e4b\u540e\uff0c\u6bd4\u5982 PD-1 \u5355\u6297\u548c CTLA-4 \u5355\u6297\u7684\u8054\u5408\u5e94\u7528\u3002\u591a\u4e2a\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u6cbb\u7597\u6700\u5f00\u59cb\u662f\u6e90\u4e8e\u9ed1\u8272\u7d20\u7624\uff0c\u540e\u6765\u5728\u80a0\u764c\u5f53\u4e2d\u6709\u63a2\u7d22\uff0c\u4eca\u5e74\u7684 POST-ASCO GI \u4f1a\u8bae\u62a5\u9053\u4e86\u7528\u4e8e\u80a0\u764c\u7684\u8054\u5408\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">PD-1 \u6297\u4f53\u8054\u5408\u5316\u7597\u5728\u80ba\u764c\u4e2d\u5df2\u7ecf\u5f00\u5c55\u7684\u5f88\u6210\u529f\u3002\u80ba\u764c\u9886\u57df\u4e5f\u6709\u514d\u75ab\u8054\u5408\u9776\u5411\u7684\u7814\u7a76\u63a2\u7d22\uff0c\u5728\u80c3\u764c\u5f53\u4e2d\uff0c\u7c7b\u4f3c\u7684\u8054\u5408\u6a21\u5f0f\u4e5f\u521d\u6b65\u770b\u5230\u4e86\u5e0c\u671b\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u4eca\u5e74\u5728 ASCO-GI \u4f1a\u8bae\u4e0a\u62a5\u9053\u7684\u4e00\u9879\u7814\u7a76\uff0c\u9488\u5bf9 HER-2 \u9633\u6027\u665a\u671f\u80c3\u764c\u60a3\u8005\uff0c\u91c7\u7528 PD-1 \u8054\u5408 HER-2 \u6291\u5236\u5242\u518d\u8054\u5408\u5316\u7597\uff0c\u53d6\u5f97\u4e86\u975e\u5e38\u597d\u7684\u7597\u6548\uff0c\u6709\u4e24\u4f8b\u60a3\u8005\u8fbe\u5230\u4e34\u5e8a\u5b8c\u5168\u7f13\u89e3\uff0c\u8054\u5408\u9776\u5411\u4e5f\u662f\u4e00\u4e2a\u975e\u5e38\u6709\u524d\u9014\u7684\u7814\u7a76\u65b9\u5411\uff0c\u4f46\u8fd9\u4e9b\u8054\u5408\u6a21\u5f0f\u90fd\u5e76\u975e\u80c3\u764c\u6cbb\u7597\u9886\u57df\u9996\u521b\u3002<\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;box-sizing: border-box;\">\u9093\u8273\u7ea2\u6559\u6388\u8ba4\u4e3a\u672a\u6765\u80c3\u764c\u6709\u673a\u4f1a\u8d85\u8d8a\u5176\u4ed6\u7624\u79cd\u7684\u7814\u7a76\u65b9\u5411\u53ef\u80fd\u662f EB\uff08Epstein-Barr\uff09\u75c5\u6bd2\u611f\u67d3\u6216 HP\uff08\u5e7d\u95e8\u87ba\u65cb\u83cc\uff09\u611f\u67d3\u6027\u80c3\u764c\u3002\u8fd9\u4e24\u79cd\u611f\u67d3\u76f8\u5173\u7684\u80c3\u764c\uff0c\u8ddf\u5e38\u89c4\u80c3\u764c\u4e0d\u540c\uff0c\u53ef\u80fd\u5bf9\u514d\u75ab\u6cbb\u7597\u7684\u53cd\u5e94\u4f1a\u66f4\u52a0\u5f3a\u70c8\uff0c\u6709\u53ef\u80fd\u662f\u6f5c\u5728\u7684\u66f4\u6709\u6548\u4eba\u7fa4\u3002<span style=\"letter-spacing: 0px;box-sizing: border-box;\">\u5bf9\u4e8e\u8fd9\u4e00\u90e8\u5206\u60a3\u8005\uff0c\u8054\u5408\u6cbb\u7597\u4e0d\u4e00\u5b9a\u9700\u8981\u5316\u7597\u6216\u8005\u9776\u5411\uff0c\u8054\u5408\u6297\u75c5\u6bd2\u6cbb\u7597\u6216\u8005\u5176\u5b83\u6cbb\u7597\u7684\u53ef\u80fd\u6027\u90fd\u662f\u5b58\u5728\u7684\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"width: 8px;height: 8px;border-radius: 50%;margin: auto;background-color: rgb(0, 0, 0);box-sizing: border-box;\"><\/section>\n<section style=\"width: 22px;margin-top: -5px;margin-right: auto;margin-left: auto;box-sizing: border-box;\">\n<section style=\"height: 20px;transform: rotate(45deg);-webkit-transform: rotate(45deg);-moz-transform: rotate(45deg);-o-transform: rotate(45deg);transform-origin: left center;-webkit-transform-origin: left center;-moz-transform-origin: left center;-o-transform-origin: left center;float: left;border-left: 1px solid rgb(28, 161, 255);border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"height: 20px;border-left: 1px solid rgb(28, 161, 255);transform: rotate(-45deg);-webkit-transform: rotate(-45deg);-moz-transform: rotate(-45deg);-o-transform: rotate(-45deg);transform-origin: right center;-webkit-transform-origin: right center;-moz-transform-origin: right center;-o-transform-origin: right center;float: right;border-top-color: rgb(28, 161, 255);border-right-color: rgb(28, 161, 255);border-bottom-color: rgb(28, 161, 255);box-sizing: border-box;\"><\/section>\n<section style=\"clear: both;box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;margin-top: -3px;border-radius: 5px;color: rgb(255, 255, 255);background-color: rgb(28, 161, 255);padding: 2px 8px;font-size: 17px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u7684\u6f5c\u5728\u83b7\u76ca\u4eba\u7fa4\u6b63\u5728\u63a2\u7d22\u4e2d\uff0c\u800c\u5982\u4f55\u6269\u5927\u83b7\u76ca\u4eba\u7fa4\u3001\u7ba1\u7406\u8d85\u8fdb\u5c55\u95ee\u9898\u662f\u514d\u75ab\u6cbb\u7597\u9762\u4e34\u7684\u6311\u6218<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"line-height: 1.75;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u7684\u4f18\u52bf\u4eba\u7fa4\uff0c\u9996\u5148\u6bd4\u8f83\u660e\u786e\u7684\u662f\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u7684\u60a3\u8005<\/strong>\uff0c<\/span>\u514d\u75ab\u6cbb\u7597\u7684\u6709\u6548\u7387\u662f\u6bd4\u8f83\u9ad8\u7684\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u7b2c\u4e8c\u4e2a\u4eba\u7fa4\uff0c\u5c31\u662f\u4e0a\u9762\u63d0\u5230\u7684EB\u75c5\u6bd2\u611f\u67d3\u6216\u8005\u5e7d\u95e8\u87ba\u65cb\u83cc\u611f\u67d3\u6027\u80c3\u764c\u60a3\u8005<\/strong>\uff0c<\/span>\u867d\u7136\u8fd8\u6ca1\u6709\u975e\u5e38\u786e\u5207\u7684\u8bd5\u9a8c\u7ed3\u679c\u51fa\u6765\uff0c\u4f46\u53ef\u80fd\u662f\u672a\u6765\u6cbb\u7597\u7279\u522b\u6709\u5e0c\u671b\u7684\u4eba\u7fa4\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u5bf9\u4e8ePD-L1\u8868\u8fbe\u9633\u6027\u7684\u60a3\u8005\uff0c\u5404\u7814\u7a76\u7ed3\u8bba\u4e0d\u4e00<\/strong>\uff0c\u5bf9\u4e8e\u8fd9\u90e8\u5206\u4eba\u7fa4<strong style=\"box-sizing: border-box;\">\uff0c\u672a\u6765\u5e94\u8be5\u8fd8\u8981\u8fdb\u4e00\u6b65\u7684\u7ec6\u5206<\/strong>\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;width: 12%;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;font-size: 8px;box-sizing: border-box;\">\n<section style=\"border-width: 3px;border-style: dotted;border-color: rgb(28, 161, 255);border-radius: 100%;display: inline-block;box-sizing: border-box;\">\n<section style=\"width: 1.6em;height: 1.6em;line-height: 1.6em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 14px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">Q<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: top;width: 88%;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin: 15px 0%;box-sizing: border-box;\">\n<section style=\"font-size: 13px;line-height: 2;padding-right: 10px;padding-left: 10px;color: rgb(160, 160, 160);box-sizing: border-box;\">\n<p style=\"white-space: normal;box-sizing: border-box;\">\u514d\u75ab\u6cbb\u7597\u76ee\u524d\u7684\u53d1\u5c55\u6709\u54ea\u4e9b\u6311\u6218\uff1f<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\">\u867d\u7136\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u5145\u6ee1\u5e0c\u671b\uff0c\u4f46\u4ecd\u7136\u5b58\u5728\u975e\u5e38\u5927\u7684\u6311\u6218\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\">\u76ee\u524d\u7684\u6570\u636e\uff0c\u53ea\u670910%-20%\u7684\u6709\u6548\u7387\uff0c\u800c\u4e14\u514d\u75ab\u6cbb\u7597\u836f\u7269\u6602\u8d35\uff0c\u4e0d\u5c11\u60a3\u8005\u83b7\u53d6\u836f\u7269\u7684\u9014\u5f84\u6709\u9650\uff0c<span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u5982\u4f55\u8fdb\u4e00\u6b65\u6269\u5927\u6709\u6548\u7387\uff0c\u662f\u76ee\u524d\u514d\u75ab\u6cbb\u7597\u6700\u5927\u7684\u6311\u6218<\/strong><\/span>\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\"><span style=\"color: rgb(0, 0, 0);\"><strong style=\"box-sizing: border-box;\">\u7b2c\u4e8c\u4e2a\u6311\u6218\u662f\uff0c\u4e0d\u540c\u4e8e\u4f20\u7edf\u5316\u7597\u3001\u9776\u5411\u6cbb\u7597\uff0c\u514d\u75ab\u6cbb\u7597\u4f1a\u51fa\u73b0\u80bf\u7624\u7684\u300c\u8d85\u8fdb\u5c55\u300d<\/strong><\/span>\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\">\u5c3d\u7ba1\u51fa\u73b0\u8fd9\u4e00\u60c5\u51b5\u7684\u6bd4\u4f8b\u4e0d\u9ad8\uff0c\u4f46\u5bf9\u4e8e\u6bcf\u4e2a\u78b0\u5230\u7684\u60a3\u8005\u53ef\u80fd\u90fd\u662f\u707e\u96be\u6027\u7684\u3002\u672a\u6765\u5982\u4f55\u53ca\u65f6\u53d1\u73b0\u53ef\u80fd\u51fa\u73b0\u300c\u8d85\u8fdb\u5c55\u300d\u7684\u60a3\u8005\uff0c\u907f\u514d\u7ed9\u4ed6\u4eec\u7528\u4e0a\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7c7b\u836f\u7269\u975e\u5e38\u91cd\u8981\u3002<\/p>\n<p style=\"box-sizing: border-box;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-bottom: -2px;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"line-height: 1.75;box-sizing: border-box;\">\n<p style=\"text-align: center;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5f80\u671f\u56de\u987e<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin: 5px 0% 10px;font-size: 12px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 8%;box-sizing: border-box;\">\n<section style=\"transform: rotateZ(90deg);-webkit-transform: rotateZ(90deg);-moz-transform: rotateZ(90deg);-o-transform: rotateZ(90deg);box-sizing: border-box;\" >\n<section style=\"margin-right: 0%;margin-left: 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;width: 100%;box-sizing: border-box;\"><img class=\"raw-image\"     style=\"vertical-align: middle;width: 100%;box-sizing: border-box;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/8-1558081182.gif\" alt=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\" title=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MjM5MzAwMjcyMA==&amp;mid=2653283728&amp;idx=2&amp;sn=1e9b659ae0de58aa6323c7d23975b248&amp;scene=21#wechat_redirect\" target=\"_blank\" ><span class=\"js_jump_icon h5_image_link\"  style=\"top: 0px;left: 0px;margin: 0px;right: 0px;bottom: 0px;\"><img class=\"raw-image\"     style=\"vertical-align: middle;box-sizing: border-box;margin: 0px;top: 0px;left: 0px;right: 0px;bottom: 0px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558081182.jpeg\" alt=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\" title=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\"  \/><\/span><\/a><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"transform: rotate(0deg);-webkit-transform: rotate(0deg);-moz-transform: rotate(0deg);-o-transform: rotate(0deg);padding: 10px;margin-left: 1em;margin-right: 1em;background-color: rgb(245, 245, 245);box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><span style=\"letter-spacing: 0px;box-sizing: border-box;\">\u626b\u63cf\u4e8c\u7ef4\u7801<\/span><\/p>\n<p style=\"box-sizing: border-box;\">\u62a5\u540d\u5b66\u4e60\u7cfb\u5217\u8bfe\u7a0b\uff01<br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"box-sizing: border-box;\">\u25bc<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;width: 45%;box-shadow: rgb(0, 0, 0) 0px 0px 0px;box-sizing: border-box;\"><img class=\"\"     style=\"width: 159px;height: 159px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/05\/0-1558081182.png\" alt=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\" title=\"\u6297\u764c\u6700\u5f3a\u97f3 | \u514d\u75ab\u7597\u6cd5\uff1a\u665a\u671f\u80c3\u764c\u6cbb\u7597\u7834\u5c40\u8005\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"width: 100%;padding-top: 1em;margin-top: -1em;border-radius: 0.5em 0.5em 1em 1em;background-color: rgb(28, 161, 255);box-sizing: border-box;\">\n<section style=\"width: 100%;border-radius: 0px 0px 0.5em 0.5em;padding: 10px;font-size: 17px;text-align: center;color: rgb(255, 255, 255);background-color: rgb(29, 161, 255);box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u8fd8\u6709\u66f4\u591a<\/strong><span style=\"letter-spacing: 0px;box-sizing: border-box;\"><span style=\"font-weight: bold;font-size: 20px;color: rgb(243, 237, 7);box-sizing: border-box;\">\u9886\u57df\u5927\u5496<\/span><span style=\"font-weight: bold;color: rgb(0, 185, 185);box-sizing: border-box;\"><span style=\"color: rgb(245, 245, 245);box-sizing: border-box;\">\u4e3a<\/span><\/span><strong style=\"box-sizing: border-box;\">\u60a8\u89e3\u7591\u7b54\u60d1\uff01<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"box-sizing: border-box;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 12px;color: rgba(62, 62, 62, 0.69);box-sizing: border-box;\">\n<p style=\"text-align: right;box-sizing: border-box;\">NP\/IO\/3924\/04\/20\/19-04\/19\/20<\/p>\n<p style=\"text-align: right;box-sizing: border-box;\">\u9898\u56fe\uff1a<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u4e24\u5e74\uff0c\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u5174\u8d77\u5e76\u8fc5\u901f\u6210\u4e3a\u5404\u5927\u56fd\u9645\u4f1a\u8bae\u7684\u70ed\u70b9\u3002 \u76ee\u524d\uff0c\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u7b49\u6297 PD-1 \u6297\u4f53\u5728\u80c3\u764c\u540e\u7ebf\u6cbb\u7597\u5df2 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":99162,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/99161"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=99161"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/99161\/revisions"}],"predecessor-version":[{"id":99166,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/99161\/revisions\/99166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/99162"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=99161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=99161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=99161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}